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Introduction: Healthcare workers (HCWs) are at increased risk of acquiring the COVID-19 disease, if there is a breach in the personal protection while managing patients. Objectives: 1. To estimate the pattern of risk exposure among healthcare workers exposed to confirmed cases of COVID-19 working in non-COVID zones of a Teaching Hospital, North-East India. 2. To determine the association between pattern of exposure with their COVID-19 status. Materials and Method: This was a hospital-based cross-sectional study conducted among all HCWs who had occupational exposure to laboratory confirmed COVID-19 cases between July and September 2020 in-non COVID zones of a major tertiary care hospital in Tripura. Results: The present study showed that 215 HCWs were exposed to confirmed cases of COVID-19 while working in non-COVID zones of the hospital. Among the exposed, 39.5% of HCWs had high-risk exposure and 8.8% of HCWs were detected as COVID-19 positive. A majority of the study subjects experienced exposure in the hospital wards (66.0%), in surgical departments (19.5%), had close contact (less than one meter distance) with positive COVID-19 cases (73.5%), and had an exposure of more than 15 minutes (51.2%). The COVID status of the exposed HCWs was significantly associated with no source control (P = 0.016), close contact with COVID-19 positive cases (P = 0.026), more duration of exposure (P < 0.05), use of any PPE (P = 0.000). COVID status was also significantly associated with the high-risk exposure of the participants (P = 0.000). Conclusion: Strict enforcement of the infection control measures like universal precautions should be practiced by HCWs to prevent hospital-acquired infections.
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Background: Vaccines against COVID-19 plays an important role in limiting the spread of SARS-CoV-2 infections and also in curbing mortality and morbidity due to COVID-19. Objective: To estimate the anti-spike antibody response after receiving the second dose of SARS-CoV-2 vaccines amongst health care workers of a tertiary care hospital in Tripura, India. Materials and Method: A cross- sectional study was conducted from 1 July to 20 August 2021 at Agartala Government Medical College and GBP Hospital, Agartala among 561 health care workers who had received first and second doses of SARS-CoV-2 vaccines and had completed 14 days after receiving the second dose. Results: The present study showed that health care workers who had received both doses of COVID-19 vaccine had 99.5% seropositivity to anti-spike antibody. The median SARS-CoV-2 anti-spike antibody titter was 250 with an IQR (211.55-250). Seropositivity rate was higher among Covishield recipients (99.8% [550/551]) as compared to Covaxin recipients (80% [8/10]) and it was found to be statistically significant (P = 0.000). Conclusion: The present study suggests that a good immune response was elicited against spike antigen of SARS-CoV-2 after two complete doses of Covishield (ChAdOx1-nCoV-19) or Covaxin (BBV152).
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INTRODUCTION: It is very important to analyze the factors which acts as obstacle in achieving 100% immunization among children. Lot Quality Assurance Sampling (LQAS) is one of the effective method to assess such barriers. AIM: To assess the full immunization coverage among 12 to 23-month old children of rural field practice area under Department of Community Medicine, Agartala Government Medical College and identify the factors for failure of full immunization. MATERIALS AND METHODS: A community based cross-sectional study was conducted from November 2013 to October 2014 on children aged 12 to 23 months old of area under Mohanpur Community health centre. Using LQAS technique 330 samples were selected with multi-stage sampling, each sub-centre being one lot and two calculated to be the decision value. Data was collected using pre-designed pre-tested questionnaire during home visit and verifying immunization card and analysed by computer software SPSS version 21.0. RESULTS: The full immunization coverage among 12 to 23 months old children of Mohanpur area was found as 91.67%. Out of all the 22 sub-centres, 36.36% was found under performing as per pre-fixed criteria and the main reasons for failure of full immunization in those areas are unawareness of need of subsequent doses of vaccines and illness of the children. CONCLUSION: LQAS is an effective method to identify areas of under-performance even though overall full immunization coverage is high.