Búsqueda | Portal de Búsqueda de la BVS Enfermería

1.

Inactivation of ERK1/2 Signaling in Dopaminergic Neurons by Map Kinase Phosphatase MKP3 Regulates Dopamine Signaling and Motivation for Cocaine.

Bernstein, David L; Lewandowski, Stacia I; Besada, Christina; Place, Delaney; España, Rodrigo A; Mortensen, Ole V.

J Neurosci ; 44(5)2024 Jan 31.

Artículo en Inglés | MEDLINE | ID: mdl-38296649

2.

Allosteric Modulator KM822 Attenuates Behavioral Actions of Amphetamine in Caenorhabditis elegans through Interactions with the Dopamine Transporter DAT-1.

Refai, Osama; Aggarwal, Shaili; Cheng, Mary Hongying; Gichi, Zayna; Salvino, Joseph M; Bahar, Ivet; Blakely, Randy D; Mortensen, Ole V.

Mol Pharmacol ; 101(3): 123-131, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-34906999

3.

Molecular characterization of the serotonergic transporter from the cestode Echinococcus granulosus: pharmacology and potential role in the nervous system.

Camicia, Federico; Vaca, Hugo R; Guarnaschelli, Ines; Koziol, Uriel; Mortensen, Ole V; Fontana, Andreia C K.

Parasitol Res ; 121(5): 1329-1343, 2022 May.

Artículo en Inglés | MEDLINE | ID: mdl-35169884

4.

Chemogenetic Manipulation of Dopamine Neurons Dictates Cocaine Potency at Distal Dopamine Transporters.

Brodnik, Zachary D; Xu, Wei; Batra, Aashita; Lewandowski, Stacia I; Ruiz, Christina M; Mortensen, Ole V; Kortagere, Sandhya; Mahler, Stephen V; España, Rodrigo A.

J Neurosci ; 40(45): 8767-8779, 2020 11 04.

Artículo en Inglés | MEDLINE | ID: mdl-33046544

5.

Anti-hypertensive mechanisms of cyclic depsipeptide inhibitor ligands for G_q/11 class G proteins.

Meleka, Matthew M; Edwards, Alethia J; Xia, Jingsheng; Dahlen, Shelby A; Mohanty, Ipsita; Medcalf, Matthew; Aggarwal, Shaili; Moeller, Kevin D; Mortensen, Ole V; Osei-Owusu, Patrick.

Pharmacol Res ; 141: 264-275, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30634050

6.

Molecular determinants of transport stimulation of EAAT2 are located at interface between the trimerization and substrate transport domains.

Mortensen, Ole V; Liberato, José L; Coutinho-Netto, Joaquim; Dos Santos, Wagner F; Fontana, Andréia C K.

J Neurochem ; 133(2): 199-210, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25626691

7.

Individual differences in dopamine uptake in the dorsomedial striatum prior to cocaine exposure predict motivation for cocaine in male rats.

Shaw, Jessica K; Pamela Alonso, I; Lewandowski, Stacia I; Scott, Marion O; O'Connor, Bethan M; Aggarwal, Shaili; De Biasi, Mariella; Mortensen, Ole V; España, Rodrigo A.

Neuropsychopharmacology ; 46(10): 1757-1767, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-33953341

8.

Transport rate of EAAT2 is regulated by amino acid located at the interface between the scaffolding and substrate transport domains.

Duffield, Michael; Patel, Avkash; Mortensen, Ole V; Schnur, Dora; Gonzalez-Suarez, Aneysis D; Torres-Salazar, Delany; Fontana, Andréia C K.

Neurochem Int ; 139: 104792, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32668264

9.

Identification of a Novel Allosteric Modulator of the Human Dopamine Transporter.

Aggarwal, Shaili; Liu, Xiaonan; Rice, Caitlyn; Menell, Paul; Clark, Philip J; Paparoidamis, Nicholas; Xiao, You-Cai; Salvino, Joseph M; Fontana, Andréia C K; España, Rodrigo A; Kortagere, Sandhya; Mortensen, Ole V.

ACS Chem Neurosci ; 10(8): 3718-3730, 2019 08 21.

Artículo en Inglés | MEDLINE | ID: mdl-31184115

10.

Selective activation of Dopamine D3 receptors and norepinephrine transporter blockade enhances sustained attention.

Marshall, Courtney A; Brodnik, Zachary D; Mortensen, Ole V; Reith, Maarten E A; Shumsky, Jed S; Waterhouse, Barry D; España, Rodrigo A; Kortagere, Sandhya.

Neuropharmacology ; 148: 178-188, 2019 04.

Artículo en Inglés | MEDLINE | ID: mdl-30633928

11.

Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2.

Kortagere, Sandhya; Mortensen, Ole V; Xia, Jingsheng; Lester, William; Fang, Yuhong; Srikanth, Yellamelli; Salvino, Joseph M; Fontana, Andréia C K.

ACS Chem Neurosci ; 9(3): 522-534, 2018 03 21.

Artículo en Inglés | MEDLINE | ID: mdl-29140675

12.

In Vitro Assays for the Functional Characterization of the Dopamine Transporter (DAT).

Aggarwal, Shaili; Mortensen, Ole V.

Curr Protoc Pharmacol ; 79: 12.17.1-12.17.21, 2017 Dec 20.

Artículo en Inglés | MEDLINE | ID: mdl-29261226

13.

Overview of Monoamine Transporters.

Aggarwal, Shaili; Mortensen, Ole V.

Curr Protoc Pharmacol ; 79: 12.16.1-12.16.17, 2017 Dec 20.

Artículo en Inglés | MEDLINE | ID: mdl-29261228

14.

MAP Kinase Phosphatase 3 (MKP3) Preserves Norepinephrine Transporter Activity by Modulating ERK1/2 Kinase-Mediated Gene Expression.

Mortensen, Ole V; Larsen, Mads B; Amara, Susan G.

Front Cell Neurosci ; 11: 253, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-28878626

15.

Designing modulators of monoamine transporters using virtual screening techniques.

Mortensen, Ole V; Kortagere, Sandhya.

Front Pharmacol ; 6: 223, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26483692

16.

Dynamic regulation of the dopamine transporter.

Mortensen, Ole V; Amara, Susan G.

Eur J Pharmacol ; 479(1-3): 159-70, 2003 Oct 31.

Artículo en Inglés | MEDLINE | ID: mdl-14612147

17.

MKP3 eliminates depolarization-dependent neurotransmitter release through downregulation of L-type calcium channel Cav1.2 expression.

Mortensen, Ole V.

Cell Calcium ; 53(3): 224-30, 2013 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-23337371

18.

A catecholamine transporter from the human parasite Schistosoma mansoni with low affinity for psychostimulants.

Larsen, Mads B; Fontana, Andréia C K; Magalhães, Lizandra G; Rodrigues, Vanderlei; Mortensen, Ole V.

Mol Biochem Parasitol ; 177(1): 35-41, 2011 May.

Artículo en Inglés | MEDLINE | ID: mdl-21251927

19.

Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin.

Fontana, Andréia C K; Sonders, Mark S; Pereira-Junior, Olavo S; Knight, Matty; Javitch, Jonathan A; Rodrigues, Vanderlei; Amara, Susan G; Mortensen, Ole V.

Eur J Pharmacol ; 616(1-3): 48-57, 2009 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-19549517

20.

Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters.