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J Nanosci Nanotechnol ; 10(2): 1255-60, 2010 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-20352785

RESUMEN

In this study, nanocapsules of poly(L-lactic acid) (PLLA) containing lavender oil were synthesized by solvent evaporation emulsion. Poly(L-lactic acid) is a biodegradable aliphatic polyester derived from lactic acid formed by bacterial fermentation of glucose-rich substances. Lavender oil is a plant extract that finds uses in phytotherapy. It is reputed as anti-septic, anti-depressant and sleep promoter. Encapsulation is a technique used to encase tiny oil droplets with a thin and permeable coating that allows for a controlled release of the volatile oil. The size and morphology of the nanocapsules were characterized by scanning electron microscope. The particle size and distribution were measured by photon correlation spectroscopy. The time-controlled release of the lavender oil was studied and the use of the lavender capsules in the remedy of sleep disorder was investigated.


Asunto(s)
Ácido Láctico/metabolismo , Lavandula , Nanocápsulas , Polímeros/metabolismo , Trastornos del Sueño-Vigilia/tratamiento farmacológico , Femenino , Fermentación , Humanos , Ácido Láctico/uso terapéutico , Masculino , Tamaño de la Partícula , Poliésteres , Polímeros/uso terapéutico , Resultado del Tratamiento
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