Effects of physical stimulation of spontaneous arteriolar vasomotion in patients of various ages undergoing rehabilitation.

On two samples of rehabilitation patients of different age groups (approx. 38 years and approx. 51 years), via a placebo-controlled study series using representative features of microcirculation, the complementary therapeutic success of additional treatment complementing the biorhythmically defined physical vasomotion stimulation was determined. The results showed that in older rehabilitation patients the amounts of characteristic microcirculatory changes were greater than in younger persons undergoing rehabilitation, but they would subside faster after termination of the additional treatment than in the younger group.

Complementary-therapeutic stimulation of deficient autorhythmic arteriolar vasomotion by means of a biorhythmically physical stimulus on the microcirculation and the immune system in 50-year-old rehabilitation patients.

As part of a placebo-controlled study series, a random sample of 50-year-old rehabilitation patients was examined to determine whether the complementary use of a physical treatment method to stimulate arteriolar vasomotion would improve the therapeutic success of established measures for the purposes of physical conditioning. The result showed that both the microcirculatory blood-flow regulation and the (cellular) immune response could be affected in a therapy-relevant manner through additional physical vasomotion stimulation.

Effects of various physical treatment methods on arteriolar vasomotion and microhemodynamic functional characteristics in case of deficient regulation of organ blood flow. Results of a placebo-controlled, double-blind study.

As part of a placebo-controlled study, high-resolution measurement methods were used to examine, on the basis of representative functional characteristics of microcirculation, whether and to what extent six different, commercially available, physical treatment devices were suitable for influencing, through complementary therapy, deficient blood-flow regulation. Of the six commercially available devices tested, two proved to be ineffective and three not effective enough to be therapeutically relevant. Only in one device was it possible to show a complementary-therapeutic effect: the device uses a specific, biorhythmically defined stimulus for vasomotion.

Influence of a specific, biorhythmically defined physical stimulus on deficient vasomotion in small-caliber arterioles in the subcutis in patients with diabetic polyneuropathy.

As part of a placebo-controlled study series on a random sample of patients with diabetic polyneuropathy and trophic skin lesions on the edge of the foot, functional characteristics of the local microcirculation and immune system were measured to check the complementary-therapy success of biorhythmically defined vasomotion stimulation. Over a 30-day treatment period, complementary-therapy success was demonstrated for an additional physical vasomotion stimulation to increase the therapeutic success of established treatment concepts.

A new ginkgo fresh plant extract increases microcirculation and radical scavenging activity in elderly patients.

INTRODUCTION: The authors investigated whether a new ginkgo biloba (ginkgo) fresh plant extract had a positive effect on microcirculation in the skin and liver of elderly individuals, and whether the extract had antioxidative properties in vivo. METHODS: In a monocentric, controlled clinical trial with 32 elderly patients, 16 patients received three 90 mg ginkgo extract tablets twice daily for 30 days, and 16 patients acted as untreated controls. On days 0, 10, 20, and 30, microcirculatory parameters were measured using intravital microscopy in combination with reflection spectrometry, and the amount of reduced glutathione in the liver. RESULTS: This new ginkgo fresh plant extract significantly increased the number of blood cell-perfused nodal points, the venular streaming flow, and the local hematocrit in treated participants compared to control participants and compared to values on day 0. The ginkgo preparation also increased microcirculation in the liver, and possessed antioxidative properties that resulted in significant increases in the amount of the radical scavenger glutathione in treated participants. CONCLUSION: The new ginkgo fresh plant extract increased the microcirculation significantly, and at the same time improved the radical scavenging capacity in elderly patients and was very well tolerated. This extract is an interesting adjuvant treatment option for patients suffering from impaired microcirculation and improves mechanisms which inhibit an accelerated expression of atherosclerosis.