Detalles de la búsqueda
1.
Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97.
Int J Mol Sci
; 24(7)2023 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37047353
2.
Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties.
Molecules
; 27(4)2022 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35209087
3.
New Pharmacological Strategies against Pancreatic Adenocarcinoma: The Multifunctional Thiosemicarbazone FA4.
Molecules
; 27(5)2022 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35268783
4.
Multi-Target Directed Ligands (MTDLs) Binding the σ1 Receptor as Promising Therapeutics: State of the Art and Perspectives.
Int J Mol Sci
; 22(12)2021 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34198620
5.
σ2 Receptor and Its Role in Cancer with Focus on a MultiTarget Directed Ligand (MTDL) Approach.
Molecules
; 26(12)2021 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34205334
6.
Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT7 Receptor.
Int J Mol Sci
; 21(24)2020 Dec 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33348850
7.
Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer.
BMC Cancer
; 17(1): 51, 2017 01 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28086830
8.
Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1.
Pharmacol Res
; 117: 67-74, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28007569
9.
Structure-activity relationship study towards non-peptidic positron emission tomography (PET) radiotracer for gastrin releasing peptide receptors: Development of [18F] (S)-3-(1H-indol-3-yl)-N-[1-[5-(2-fluoroethoxy)pyridin-2-yl]cyclohexylmethyl]-2-methyl-2-[3-(4-nitrophenyl)ureido]propionamide.
Bioorg Med Chem
; 25(1): 277-292, 2017 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27863916
10.
Novel and Selective Fluorescent σ2 -Receptor Ligand with a 3,4-Dihydroisoquinolin-1-one Scaffold: A Tool to Study σ2 Receptors in Living Cells.
Chembiochem
; 16(7): 1078-83, 2015 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-25757101
11.
Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of ß-arrestin-2.
Bioorg Med Chem
; 23(15): 4824-4830, 2015 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26081758
12.
Selective agonists for serotonin 7 (5-HT7) receptor and their applications in preclinical models: an overview.
Rev Neurosci
; 25(3): 401-15, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24622785
13.
Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HT7 receptor.
Bioorg Med Chem
; 22(5): 1736-50, 2014 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24508140
14.
Design, synthesis, lipophilic properties, and binding affinities of potential ligands in positron emission tomography (PET) for visualization of brain dopamine D4 receptors.
Chem Biodivers
; 11(2): 299-310, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24591318
15.
Nature-Inspired 1-Phenylpyrrolo[2,1-a]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance.
Pharmaceuticals (Basel)
; 17(4)2024 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38675499
16.
The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line.
Mol Cancer
; 12: 47, 2013 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-23705854
17.
Novel highly potent serotonin 5-HT7 receptor ligands: structural modifications to improve pharmacokinetic properties.
Bioorg Med Chem Lett
; 23(22): 6083-6, 2013 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24100077
18.
Towards metabolically stable 5-HT7 receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.
Exp Brain Res
; 230(4): 569-82, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23571499
19.
Investigation of σ receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines.
Bioorg Med Chem
; 21(7): 1865-9, 2013 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23415062
20.
Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells.
Pharmacol Rep
; 75(6): 1588-1596, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37796435