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1.
Opt Express ; 32(4): 6587-6596, 2024 Feb 12.
Artículo en Inglés | MEDLINE | ID: mdl-38439358

RESUMEN

We propose using physical-informed neural network (PINN) for power evolution prediction in bidirectional Raman amplified WDM systems with Rayleigh backscattering (RBS). Unlike models based on data-driven machine learning, PINN can be effectively trained without preparing a large amount of data in advance and can learn the potential rules of power evolution. Compared to previous applications of PINN in power prediction, our model considers bidirectional Raman pumping and RBS, which is more practical. We experimentally demonstrate power evolution prediction of 200 km bidirectional Raman amplified wavelength-division multiplexed (WDM) system with 47 channels and 8 pumps using PINN. The maximum prediction error of PINN compared to experimental results is only 0.38 dB, demonstrating great potential for application in power evolution prediction. The power evolution predicted by PINN shows good agreement with the results simulated by traditional numerical method, but its efficiency is more suitable for establishing models and calculating noise, providing convenience for subsequent power configuration optimization.

2.
Front Immunol ; 15: 1401528, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38881902

RESUMEN

CD24 is a glycosylphosphatidylinositol-anchored protein that is expressed in a wide range of tissues and cell types. It is involved in a variety of physiological and pathological processes, including cell adhesion, migration, differentiation, and apoptosis. Additionally, CD24 has been studied extensively in the context of cancer, where it has been found to play a role in tumor growth, invasion, and metastasis. In recent years, there has been growing interest in CD24 as a potential therapeutic target for cancer treatment. This review summarizes the current knowledge of CD24, including its structure, function, and its role in cancer. Finally, we provide insights into potential clinical application of CD24 and discuss possible approaches for the development of targeted cancer therapies.


Asunto(s)
Antígeno CD24 , Neoplasias , Humanos , Antígeno CD24/metabolismo , Neoplasias/terapia , Neoplasias/metabolismo , Neoplasias/tratamiento farmacológico , Neoplasias/inmunología , Animales , Terapia Molecular Dirigida
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