Detalles de la búsqueda
1.
Novel imidazolone derivatives as potential dual inhibitors of checkpoint kinases 1 and 2: Design, synthesis, cytotoxicity evaluation, and mechanistic insights.
Bioorg Chem
; 149: 107471, 2024 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-38823311
2.
Designing Potent Anti-Cancer Agents: Synthesis and Molecular Docking Studies of Thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidine Derivatives.
Molecules
; 29(5)2024 Feb 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38474579
3.
Nanoparticles of a Pyrazolo-Pyridazine Derivative as Potential EGFR and CDK-2 Inhibitors: Design, Structure Determination, Anticancer Evaluation and In Silico Studies.
Molecules
; 28(21)2023 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-37959672
4.
New thiophene, thienopyridine and thiazoline-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents and multitargeting kinase inhibitors.
Bioorg Chem
; 127: 105964, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35759881
5.
Design, synthesis, anti-inflammatory evaluation and molecular docking of novel thiophen-2-ylmethylene-based derivatives as potential TNF-α production inhibitors.
Bioorg Chem
; 122: 105726, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35364361
6.
Synthesis, anticancer evaluation and molecular docking of new benzothiazole scaffolds targeting FGFR-1.
Bioorg Chem
; 119: 105504, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34836644
7.
Design, synthesis, and anti-cancer evaluation of new pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as potential EGFRWT and EGFRT790M inhibitors and apoptosis inducers.
J Enzyme Inhib Med Chem
; 37(1): 1053-1076, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35821615
8.
Antibacterial and anticancer profiling of new benzocaine derivatives: Design, synthesis, and molecular mechanism of action.
Arch Pharm (Weinheim)
; 355(4): e2100451, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35102593
9.
Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2.
Molecules
; 27(7)2022 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35408446
10.
New 1,2,3-Triazole-Coumarin-Glycoside Hybrids and Their 1,2,4-Triazolyl Thioglycoside Analogs Targeting Mitochondria Apoptotic Pathway: Synthesis, Anticancer Activity and Docking Simulation.
Molecules
; 27(17)2022 Sep 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36080455
11.
Design, Synthesis, Anticancer Activity and Molecular Docking of New 1,2,3-Triazole-Based Glycosides Bearing 1,3,4-Thiadiazolyl, Indolyl and Arylacetamide Scaffolds.
Molecules
; 27(20)2022 Oct 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36296551
12.
Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques.
Molecules
; 27(3)2022 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35164382
13.
Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity.
Bioorg Chem
; 111: 104827, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33798845
14.
New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies.
Bioorg Chem
; 114: 105078, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34161878
15.
New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2.
Bioorg Chem
; 114: 105117, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34214752
16.
Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazole-thienopyrimidine hybrid glycosides targeting EGFR.
J Enzyme Inhib Med Chem
; 36(1): 504-516, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33504239
17.
Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide-Glycyrrhetinic-Acid-Based Derivatives.
Molecules
; 26(15)2021 Jul 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34361728
18.
Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase.
Bioorg Chem
; 101: 103916, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32559576
19.
Novel heterocyclic hybrids of pyrazole targeting dihydrofolate reductase: design, biological evaluation and in silico studies.
J Enzyme Inhib Med Chem
; 35(1): 1491-1502, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32668994
20.
Chiral Pyridine-3,5-bis- (L-phenylalaninyl-L-leucinyl) Schiff Base Peptides as Potential Anticancer Agents: Design, Synthesis, and Molecular Docking Studies Targeting Lactate Dehydrogenase-A.
Molecules
; 25(5)2020 Feb 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-32121469