RESUMEN
CONTEXT: Clinical symptoms of Brunner's gland (BG) hamartoma are rare. Most lesions are small and asymptomatic. Symptomatic BG hamartoma may mimic a malignancy of the duodenal-pancreatic area. Though standard mucosal biopsies are inferiorly diagnostic due to normal duodenal mucosa surrounding, a biopsy was indicated in this case. CASE REPORT: We report the case of a 37-year-old man with a large BG hamartoma mimicking a malignancy. Preoperatively the biopsy led to an inconclusive diagnosis. Due to its large size and its presence of symptoms, a surgical excision was performed. CONCLUSION: BG hamartoma may be a rare indication for surgery.
Asunto(s)
Glándulas Duodenales , Enfermedades Duodenales/complicaciones , Obstrucción Duodenal/etiología , Hemorragia Gastrointestinal/etiología , Hamartoma/complicaciones , Dolor Abdominal/etiología , Adulto , Enfermedades Duodenales/diagnóstico , Enfermedades Duodenales/patología , Enfermedades Duodenales/cirugía , Hamartoma/diagnóstico , Hamartoma/patología , Hamartoma/cirugía , Humanos , Masculino , Tomografía Computarizada por Rayos XRESUMEN
A 14-year-old boy presented with acute abdominal pain, vomiting and diarrhoea. Colo-colic intussusception was diagnosed by means of a colonic contrast X-ray. The intussusception was successfully reduced during this procedure. Hundreds of polyps were seen throughout the entire colon. Genetic research showed a mutation of the MutYH gene. Proctocolectomy with ileoanal pouch anastomosis was carried out. The pathology specimen showed an intramucosal carcinoma and multiple adenomas. MutYH-associated polyposis coli is an autosomal recessive disease that occurs as a result of a mutation in the MutYH gene. This will lead to polyposis coli. An intussusception is a rarely seen symptom. Patients need preventive surgical treatment because of the high risk developing a colorectal carcinoma.