RESUMEN
BACKGROUND: Shunt surgery is frequently chosen to manage periventricular metastasis of pineal region tumours which obscured the floor of the third ventricle. However, this procedure falls short due to distant metastasis. Neuronavigation-guided endoscopic surgery offers a viable alternative. PATIENT: A 17-year-old man became symptomatic from widespread periventricular metastasis of a pineal region tumour which completely obscured the floor of the third ventricle. RESULTS: Endoscopic tumour biopsy followed by neuronavigation-guided endoscopic third ventriculotomy was performed successfully. CONCLUSION: This case report emphasizes the value of neuronavigation-guided endoscopic third ventriculostomy as a feasible surgical alternative for pineal region tumours with widespread periventricular metastasis that obscure the third ventricular floor.
Asunto(s)
Neoplasias del Ventrículo Cerebral/cirugía , Germinoma/cirugía , Neuroendoscopía/métodos , Neuronavegación/métodos , Pinealoma/cirugía , Tercer Ventrículo/cirugía , Adolescente , Neoplasias del Ventrículo Cerebral/diagnóstico por imagen , Neoplasias del Ventrículo Cerebral/secundario , Germinoma/diagnóstico por imagen , Germinoma/secundario , Humanos , Masculino , Neuroendoscopía/instrumentación , Neuronavegación/instrumentación , Pinealoma/diagnóstico por imagen , Pinealoma/patología , Radiografía , Tercer Ventrículo/patología , Resultado del TratamientoRESUMEN
BACKGROUND: Stereotactic radiosurgery uses a single fraction high dose radiation while stereotactic radiotherapy uses multifractionated lower dose focused radiation. MATERIALS AND METHODS: Radiosurgery used rigid CRW head frame while stereotactic radiotherapy utilized GTC or HNL relocatable frames. Stereotactic planning and radiation involved Radionics X-plan and LINAC system. RESULTS: Since December 2001, we have treated 83 lesions from 77 patients using either radiosurgery or fractionated stereotactic radiotherapy. Eighty six percent (86%) of our treated lesions showed favourable outcomes with median follow-up of 32 months (0-7 years). CONCLUSIONS: Our lessons from LINAC precision radiation therapy uphold its value as a promising and effective tool in treating a range of nervous system pathologies.
Asunto(s)
Neoplasias Encefálicas/radioterapia , Neoplasias Encefálicas/cirugía , Fraccionamiento de la Dosis de Radiación , Malformaciones Arteriovenosas Intracraneales/radioterapia , Malformaciones Arteriovenosas Intracraneales/cirugía , Radiocirugia , Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
Intracranial hemorrhage is an uncommon complication of phenylpropanolamine. There is an increasing awareness of this complication in the West. However, to the best of our knowledge there have been no cases reported from India. Here we report a patient who developed Intraventricular hemorrhage following ingestion of Phenylpropanolamine, from which he made an uneventul recovery over the next two weeks.
Asunto(s)
Hemorragia Cerebral/inducido químicamente , Ventrículos Cerebrales , Descongestionantes Nasales/efectos adversos , Fenilpropanolamina/efectos adversos , Adulto , Hemorragia Cerebral/diagnóstico por imagen , Humanos , India , Angiografía por Resonancia Magnética , Masculino , Tomografía Computarizada por Rayos XAsunto(s)
Antígenos de Superficie de la Hepatitis B/análisis , Hepatitis B/complicaciones , Hepatitis B/epidemiología , Leishmaniasis Visceral/complicaciones , Adolescente , Adulto , Estudios de Casos y Controles , Femenino , Hepatitis B/inmunología , Humanos , India/epidemiología , Leishmaniasis Visceral/inmunología , Masculino , Persona de Mediana Edad , PrevalenciaRESUMEN
Percutaneous retrogasserian glycerol rhizotomy has shown encouraging results in the treatment of trigeminal neuralgia. An experimental study was undertaken using a rat sciatic nerve model to elucidate the mechanism of action of anhydrous glycerol and to study the acute changes which develop within one week. Extraneural glycerol was applied in 20 adult Wistar rats. Groups of five animals were sacrificed at days 1, 3, 5 and 7 respectively. The sciatic nerve of the opposite limb in the same animals was used as a control. The nerve were examined with light and electron microscopy including a morphometric study to assess the type of fibres affected. The specific pattern of involvement of larger and medium sized myelinated fibres with relative preservation of unmyelinated fibres was noted.