1.
J Org Chem
; 84(1): 53-59, 2019 Jan 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-30566353
RESUMEN
A novel rhodium-catalyzed tandem reaction of isocyanides with azides and various oxygen nucleophiles has been developed. The reaction provides a simple and highly efficient one-pot synthesis of various N-sulfonyl/acylisoureas with broad substrate scope in an atom-economical manner from readily available starting materials in a highly stereoselective manner.
2.
Chem Commun (Camb)
; 54(59): 8229-8232, 2018 Jul 19.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29987288
RESUMEN
A thermally induced novel formal [4+2] cycloaddition of cyclobutenones with electron-deficient alkynes under metal-free conditions has been developed for the first time. The reaction can proceed in a highly regioselective manner and provides a straightforward and efficient method for the synthesis of 4-pyridone derivatives from readily available starting materials in a single step.