Papillary muscle ventricular arrhythmias in patients with arrhythmic mitral valve prolapse: Electrophysiologic substrate and catheter ablation outcomes.

BACKGROUND: Mitral valve prolapse (MVP) is a common valve condition and has been associated with sudden cardiac death. Premature ventricular contractions (PVCs) from the papillary muscles (PMs) may play a role as triggers for ventricular fibrillation (VF) in these patients. OBJECTIVES: To characterize the electrophysiological substrate and outcomes of catheter ablation in patients with MVP and PM PVCs. METHODS: Of 597 patients undergoing ablation of ventricular arrhythmias during the period 2012-2015, we identified 25 patients with MVP and PVCs mapped to the PMs (64% female). PVC-triggered VF was the presentation in 4 patients and a fifth patient died suddenly during follow-up. The left ventricle ejection fraction (LVEF) was 50.5% ± 11.8% and PVC burden was 24.4% ± 13.1%. A cardiac magnetic resonance imaging was performed in nine cases and areas of late gadolinium enhancement were found in four of them. A detailed LV voltage map was performed in 11 patients, three of which exhibited bipolar voltage abnormalities. Complete PVC elimination was achieved in 19 (76%) patients and a significant reduction in PVC burden was observed in two (8%). In patients in which the ablation was successful, the PVC burden decreased from 20.4% ± 10.8% to 6.3% ± 9.5% (P = 0.001). In 5/6 patients with depressed LVEF and successful ablation, the LV function improved postablation. No significant differences were identified between patients with and without VF. CONCLUSIONS: PM PVCs are a source of VF in patients with MVP and can induce PVC-mediated cardiomyopathy that reverses after PVC suppression. Catheter ablation is highly successful with more than 80% PVC elimination or burden reduction.

Synthesis of photochromic oligophenylenimines: optical and computational studies.

Phenyleneimine oligomers 4,4'-(((1E,1'E)-(((1E,1'E)-(1,4-phenylenebis-(azanylylidene))bis(methanylylidene))bis(2,5-bis(octyloxy)-4,1-phenylene))bis(methanylyl-idene))-bis(azanylylidene))dianiline (OIC1MS) and 7,7'-(((1E,1'E)-(((1E,1'E)-((9H-fluorene-2,7-diyl)bis(azanylylidene))bis(methanylylidene))bis(2,5-bis(octyloxy)-4,1phenylene))bis- (methanylylidene))bis(azanylylidene))bis(9H-fluoren-2-amine) (OIC2MS) were prepared by means of conventional and mechanochemical synthesis and characterized by FT-IR, 1H- and 13C-NMR techniques. The optical properties of the compounds were studied in solution by using UV-visible spectroscopy, and the optical effects were analyzed as a function of solvent. The results show that OIC2MS exhibits interesting photochromic properties. Furthermore, the structural and electronic properties of the compounds were analyzed by TD-DFT. It was found that the mechanosynthesis is an efficient method for the synthesis of both tetraimines.

Understanding the support for gender-based harassment perpetrators: the role of closeness and empathy.

Introduction: Gender-based harassment is a pressing social challenge urgently demanding eradication. While social movements emphasize supporting victims, societal responses sometimes lean toward exculpating perpetrators. This study examines two factors influencing this exoneration: closeness to perpetrators and empathy focus. Methods: A total of 345 participants took part in an experimental design to assess how closeness to perpetrators (close vs. distant) and empathy focus (on the perpetrator vs. victim vs. control) impact the moral justification of harassment and the dehumanization of both parties. Results and discussion: Results indicate that closeness and empathizing with perpetrators lead to greater leniency-more moral justification and less dehumanization of the perpetrator. Heightened moral justification for close perpetrators is mediated by increased empathy toward them and decreased empathy for victims, and reduced dehumanization of close perpetrators corresponds to heightened empathy toward them. This research highlights how closeness and empathy, two initially positive factors, can foster tolerance toward gender harassment.

Outcomes of robotic nipple-sparing mastectomy versus conventional nipple-sparing mastectomy in women with breast cancer: a systematic review and meta-analysis.

The promising results of the robotic approach for multiple cancer operations has led to interest in the potential of robotic nipple-sparing mastectomy (R-NSM); however, further studies are required to compare the benefits and complications of this approach with those of conventional open nipple-sparing mastectomy (C-NSM). We performed a meta-analysis to compare surgical complications of R-NSM versus C-NSM. We performed a review of literature through June 2022 in PubMed, Scopus, and EMBASE. We included randomized controlled trials (RCTs), cohorts, case-control studies, and case series with > 50 patients comparing the two techniques. Separate meta-analyses were conducted according to study design. From 80 publications, we identified six studies. The sample size ranged from 63 to 311 mastectomies from 63 to 275 patients. The tumor size and disease stage were similar between groups. The positive margin rate was 0-4.6% in the R-NSM arm and 0-2.9% in the C-NSM arm. Four studies reported early recurrence data, which were similar between groups (R-NSM: 0%, C-NSM: 0-8%). The R-NSM group had a lower rate of overall complications compared to the C-NSM group in cohorts/RCTs (RR = 0.68, 95%CI 0.49-0.96). In case-control studies, rate of necrosis was lower with R-NSM. Operative time was significantly longer in the R-NSM group in cohort/RCTs. In early experience with R-NSM, R-NSM had a lower overall complication rate compared to C-NSM in cohorts/RCTs. While these data are promising, our results show variability and heterogeneity limiting definitive conclusions. Additional trials are needed to guide the role of R-NSM and its oncologic outcomes.

Cultural variations in perceptions and reactions to social norm transgressions: a comparative study.

Introduction: Humans are similar but behave differently, and one main reason is the culture in which they are born and raised. The purpose of this research is to examine how the perception and reaction to those who transgress social norms may vary based on the individualism/collectivism of their culture. Methods: A study (N = 398) conducted in the United Kingdom, Spain, and China showed differences in the perception and reaction to incivilities based on individualism/collectivism. Results: People from highly collective countries (China) perceive uncivil transgressors as immoral and enact more social control over them than people from highly individualistic countries (U.K.). They also experience more discomfort when facing uncivil transgressors, and this discomfort mediates the increasing immorality perceived on the agents of incivilities in contrast with people from less collective countries. Discussion: Our findings provide insights into how cultural factors shape individuals' perceptions of social norm violations and emphasize the importance of considering cultural differences when addressing incivility.

The impact of helping behavior on outgroup infrahumanization.

Infrahumanization research has verified that in intergroup contexts, there is a strong tendency to attribute secondary emotions, which are uniquely human, to the ingroup, while limiting that attribution in outgroups. Experiments have shown it to be as common as ingroup bias. However, it is not yet known what characteristics may mitigate this trend. This paper presents two studies. The first analyzes the impact of helping behavior on attributions of human traits to two fictitious groups. The second study's objective was to determine if members of the Spanish ingroup would infrahumanize an Ethiopian outgroup less when that outgroup performs prosocial behavior towards another group. Infrahumanization was determined by a lexical decision task, using the names of ingroup and outgroup members as priming. The results demonstrate that describing a fictitious group in altruistic terms increases their human profile (experiment one) and reduces infrahumanization (experiment two).

A quantum walk simulation of extra dimensions with warped geometry.

We investigate the properties of a quantum walk which can simulate the behavior of a spin 1/2 particle in a model with an ordinary spatial dimension, and one extra dimension with warped geometry between two branes. Such a setup constitutes a [Formula: see text] dimensional version of the Randall-Sundrum model, which plays an important role in high energy physics. In the continuum spacetime limit, the quantum walk reproduces the Dirac equation corresponding to the model, which allows to anticipate some of the properties that can be reproduced by the quantum walk. In particular, we observe that the probability distribution becomes, at large time steps, concentrated near the "low energy" brane, and can be approximated as the lowest eigenstate of the continuum Hamiltonian that is compatible with the symmetries of the model. In this way, we obtain a localization effect whose strength is controlled by a warp coefficient. In other words, here localization arises from the geometry of the model, at variance with the usual effect that is originated from random irregularities, as in Anderson localization. In summary, we establish an interesting correspondence between a high energy physics model and localization in quantum walks.

Gender inequality in incivility: Everyone should be polite, but it is fine for some of us to be impolite.

Civility is formed by social norms that guide our behavior and allow us to interact appropriately with others. These norms affect everyone and are learned through the socialization process. However, in the same process, people also learn gender norms that dictate how men and women should behave, leading to gender stereotypes and differentiated behavioral characteristics. The purpose of this research is to examine the relationship between gender and civility, and how we react to those who behave uncivilly given their gender. The results of Study 1 (N = 153) showed that even in a fictional and gender-neutral society, uncivil behaviors were associated with stereotypically masculine characteristics, and those who behaved uncivilly were dehumanized. In Study 2 (N = 144), gender differences were observed in incivility. Women were harsher when facing uncivil transgressors than men, especially if the transgressor was another woman. Our findings support the notion that gender norms are applied to civility, leading those supposedly equal social norms to unequal perceptions and evaluations.

Comparative Analysis of a Modified Secondary Healing Protocol for Fingertip Amputations and Non-microsurgical Reconstruction Techniques.

Objective To describe and compare the results obtained with a secondary healing protocol for fingertip amputations and their relationship to injury severity according to the Allen classification. Methods Medical records of 127 fingertip injuries were revised, and a retrospective, comparative, analytical study the amputations treated conservatively was performed. Injury characteristics, healing time, and complications were described and analyzed. Results Between April 2017 and May 2019, 127 fingertip injuries were treated conservatively. The average age of the sample was of 28.33 years. The average healing time was of 4.31 weeks. The complications during the follow-up were observed in 18.9% ( n = 24) of the cases, but none require revision treatment. A statistically significant relationship between the development of complications and treatment revision according to the Allen classification was not found ( p ≥ 0.05). Conclusion The proposed secondary healing protocol has shown to be safe and effective in types 1 to 3 fingertip amputations in the Allen classification, and it should be included as a therapeutic option even in injuries of greater extension than those that have traditionally been limited to.

Dehumanization as a Response to Uncivil and Immoral Behaviors.

Theoretical approaches to dehumanization consider civility to be an attribute of human uniqueness (HU). However, studies that explore the links between civility and humanness are scarce. More precisely, the present research tests whether there is a consistent relationship between civility and HU. Method and results: The first study (N = 192; Mage = 19.91; SD = 2.70; 69% women) shows that individuals infer more HU traits in the agents of civil behaviors compared to agents of other positive behaviors that are not related to civility. The second study (N = 328; Mage = 19.69; SD = 3.65; 77% women) reveals that uncivil and immoral behaviors displayed a similar pattern of inference of HU traits; however, moral behaviors were more associated with human nature than civil behaviors. Conclusions: Overall, results confirmed that civil behaviors facilitate the inference of humanness, specifically of HU traits, and that civil and moral behaviors are not equivalent in terms of the human inferences to which they lead.

Factors associated with in-hospital mortality and readmission in a cohort of patients treated with noninvasive ventilation during emergency department or out-of-hospital emergency care: the VentilaMadrid study. / Factores asociados a la mortalidad intrahospitalaria y reingreso en una cohorte tratada con ventilación no invasiva en urgencias extrahospitalarias y hospitalarias: estudio VentilaMadrid.

OBJECTIVES: To describe clinical, outcome, and risk factors in a cohort of patients treated with noninvasive ventilation (NIV) in a hospital emergency department (ED) or by out-of-hospital emergency medical services (OHEMSs). MATERIAL AND METHODS: Multicenter, prospective cohort study enrolling consecutive patients with acute pulmonary edema and/or exacerbated chronic obstructive pulmonary disease who were treated with NIV between November 2018 and November 2020 in a hospital ED or OHEMS setting in Madrid. We recorded baseline data, variables related to the acute episode, and outcome variables, including in-hospital mortality and 30-day readmission. RESULTS: A total of 317 patients were included; 132 (41.6%) were treated in an OHEMS setting and 185 (58.4%) in a hospital ED. Forty-seven (16.3%) in-hospital deaths occurred, and 78 patients (28.8%) were readmitted within 30 days. Mortality in the hospital ED and OHEMS subsamples did not differ, but the patients who received NIV in an OHEMS setting had a lower 30-day readmission rate. On multivariate analysis, in-hospital mortality was associated with prior dependence in activities of daily living in the multivariate analysis (odds ratio [OR], 2.4; 95% CI, 1.11-5.27) and a low-moderate score on the Simplified Acute Physiology Score II (SAPS II) versus a high-very high one (OR, 2.69; 95% CI, 1.26-5.77). Mortality after OHEMS ventilation was associated with discontinuance of NIV during transfer (OR, 8.57; 95% CI, 2.19-33.60). Readmission within 30 days was associated with group (in-hospital ED application of NIV) (OR, 3.24; 95% CI, 2.62-6.45) and prior dependence (OR, 2.08; 95% CI, 1.02-4.22). CONCLUSION: Patients treated in the hospital ED and OHEMS setting have similar baseline characteristics, although acute episodes were more serious in the OHEMS group. No significant differences were found related to in-hospital mortality. Higher mortality was associated with dependence, a SAPS II score greater than 52, and discontinuance of NIV. Readmission was associated with dependence and NIV treatment in the hospital ED setting.

OBJETIVO: Describir las características clínicas, evolutivas y los factores pronóstico de una cohorte de pacientes tratados con ventilación no invasiva (VNI) en servicios de urgencias extrahospitalarios (SUEH) y hospitalarios (SUH). METODO: Estudio de cohortes multicéntrico, prospectivo con inclusión consecutiva de pacientes con edema agudo de pulmón o agudización de enfermedad pulmonar obstructiva crónica tratados con VNI entre noviembre 2018 y noviembre de 2020 en SUEH y SUH de la Comunidad de Madrid. Se recogieron características basales, del episodio agudo, así como variables de resultado incluyendo la mortalidad hospitalaria y el reingreso a 30 días. RESULTADOS: Se incluyeron 317 pacientes, 132 (41,6%) en SUEH y 185 (58,4%) en SUH. Hubo 47 muertes intrahospitalarias (16,3%) y 78 reingresos a los 30 días (28,8%). No hubo diferencias en la mortalidad, pero el grupo VNI-SUEH tuvo menor reingreso a 30 días. En el análisis multivariado la mortalidad intrahospitalaria se asoció con la dependencia previa (OR = 2,4; IC 95%: 1,11-5,27) y el SAPS-II bajo-moderado frente al alto-muy alto (OR = 2,69; IC 95%: 1,26-5,77). En la cohorte extrahospitalaria, la mortalidad intrahospitalaria se asoció con la retirada de la VNI en la transferencia del paciente (OR = 8,57; IC 95%: 2,19-33,60). Los reingresos a los 30 días se asociaron con inicio de VNI en el hospital (OR = 3,24; IC 95%: 2,62-6,45) y dependencia previa (OR = 2,08; IC 95%: 1,02-4,22). CONCLUSIONES: Los pacientes de ambos grupos, SUH y SUEH, tienen un perfil clínico basal similar, aunque con mayor gravedad del episodio en el grupo SUEH. No se encontraron diferencias estadísticamente significativas en la mortalidad intrahospitalaria. Se asociaron a una mayor mortalidad la dependencia, la escala SAPS-II > 52 y la retirada de la VNI. El reingreso se asoció con la dependencia y pertenecer al grupo SUH.

Effect of EARLY administration of DEXamethasone in patients with COVID-19 pneumonia without acute hypoxemic respiratory failure and risk of development of acute respiratory distress syndrome (EARLY-DEX COVID-19): study protocol for a randomized controlled trial.

BACKGROUND: Corticosteroids are one of the few drugs that have shown a reduction in mortality in coronavirus disease 2019 (COVID-19). In the RECOVERY trial, the use of dexamethasone reduced 28-day mortality compared to standard care in hospitalized patients with suspected or confirmed COVID-19 requiring supplemental oxygen or invasive mechanical ventilation. Evidence has shown that 30% of COVID-19 patients with mild symptoms at presentation will progress to acute respiratory distress syndrome (ARDS), particularly patients in whom laboratory inflammatory biomarkers associated with COVID-19 disease progression are detected. We postulated that dexamethasone treatment in hospitalized patients with COVID-19 pneumonia without additional oxygen requirements and at risk of progressing to severe disease might lead to a decrease in the development of ARDS and thereby reduce death. METHODS/DESIGN: This is a multicenter, randomized, controlled, parallel, open-label trial testing dexamethasone in 252 adult patients with COVID-19 pneumonia who do not require supplementary oxygen on admission but are at risk factors for the development of ARDS. Risk for the development of ARDS is defined as levels of lactate dehydrogenase > 245 U/L, C-reactive protein > 100 mg/L, and lymphocyte count of < 0.80 × 109/L. Eligible patients will be randomly assigned to receive either dexamethasone or standard of care. Patients in the dexamethasone group will receive a dose of 6 mg once daily during 7 days. The primary outcome is a composite of the development of moderate or more severe ARDS and all-cause mortality during the 30-day period following enrolment. DISCUSSION: If our hypothesis is correct, the results of this study will provide additional insights into the management and progression of this specific subpopulation of patients with COVID-19 pneumonia without additional oxygen requirements and at risk of progressing to severe disease. TRIAL REGISTRATION: ClinicalTrials.gov NCT04836780. Registered on 8 April 2021 as EARLY-DEX COVID-19.

Humanness Is Not Always Positive: Automatic Associations between Incivilities and Human Symbols.

Uncivil behavior involves an attack on social norms related to the protection of public property and respect for community life. However, at the same time, the low-frequency and relatively low-intensity damage caused by most of these behaviors could lead to incivilities being considered a typically human action. The purpose of this set of studies is to examine the automatic associations that people establish between humanness and both civic and uncivil behaviors. Across three studies, uncivil behaviors were more strongly associated with human pictures than animal pictures (study 1) and with human-related words than animal-related words (study 2). We replicated study 2 with uncivil behaviors that do not prime graphically human beings (study 3). Overall, our results showed that uncivil behaviors and civic behaviors were clearly associated with human concepts. Our findings have direct implications for the conceptualization of humanness and its denial.

Water Jet Erosion Performance of Carbon Fiber and Glass Fiber Reinforced Polymers.

Complex engineering challenges are revealed in the wind industry; one of them is erosion at the leading edge of wind turbine blades. Water jet erosive wear tests on carbon-fiber reinforced polymer (CFRP) and glass-fiber reinforced polymer (GFRP) were performed in order to determine their resistance at the conditions tested. Vacuum Infusion Process (VIP) was used to obtain the composite materials. Eight layers of bidirectional carbon fabric (0/90°) and nine glass layers of bidirectional glass cloth were used to manufacture the plates. A water injection platform was utilized. The liquid was projected with a pressure of 150 bar on the surface of the specimens through a nozzle. The samples were located at 65 mm from the nozzle at an impact angle of 75°, with an exposure time of 10, 20 and 30 min. SEM and optical microscopy were used to observe the damage on surfaces. A 3D optical profilometer helped to determine the roughness and see the scar profiles. The results showed that the volume loss for glass fiber and carbon fiber were 10 and 19 mm3, respectively. This means that the resistance to water jet erosion in uncoated glass fiber was approximately two times lower than uncoated carbon fiber.

Cholesterol-Rich Lipid Rafts as Platforms for SARS-CoV-2 Entry.

Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for human health that involves the host lipid homeostasis. Regarding, lipid rafts are functional membrane microdomains with highly and tightly packed lipid molecules. These regions enriched in sphingolipids and cholesterol recruit and concentrate several receptors and molecules involved in pathogen recognition and cellular signaling. Cholesterol-rich lipid rafts have multiple functions for viral replication; however, their role in SARS-CoV-2 infection remains unclear. In this review, we discussed the novel evidence on the cholesterol-rich lipid rafts as a platform for SARS-CoV-2 entry, where receptors such as the angiotensin-converting enzyme-2 (ACE-2), heparan sulfate proteoglycans (HSPGs), human Toll-like receptors (TLRs), transmembrane serine proteases (TMPRSS), CD-147 and HDL-scavenger receptor B type 1 (SR-B1) are recruited for their interaction with the viral spike protein. FDA-approved drugs such as statins, metformin, hydroxychloroquine, and cyclodextrins (methyl-ß-cyclodextrin) can disrupt cholesterol-rich lipid rafts to regulate key molecules in the immune signaling pathways triggered by SARS-CoV-2 infection. Taken together, better knowledge on cholesterol-rich lipid rafts in the SARS-CoV-2-host interactions will provide valuable insights into pathogenesis and the identification of novel therapeutic targets.

Updating national diagnostic reference levels for interventional cardiology and methodological aspects.

The aim of this study is to propose national diagnostic reference levels (DRL) for updating in the field of interventional cardiology and to include technical details to help plan optimization. Medical physics experts and interventional cardiologists from 14 hospitals provided patient dose indicators from coronary angiography and percutaneous coronary interventions. Information about X-ray system dose settings and image quality was also provided. The dose values from 30,024 procedures and 26 interventional laboratories were recorded. The national DRLs proposed for coronary angiography and percutaneous coronary interventions were respectively 39 and 78 Gy·cm2 for air kerma area product (PKA), 530 and 1300 mGy for air kerma at reference point (Ka,r), 6.7 and 15 min of fluoroscopy time and 760 and 1300 cine images. 36% of the KAP meters required correction factors from 10 to 35%. The dose management systems should allow these corrections to be included automatically. The dose per image in cine in reference conditions differed in a factor of 5.5. Including X-ray system dose settings in the methodology provides an insight into the differences between hospitals. The DRLs proposed for Spain in this work were similar to those proposed in the last European survey. The poor correlation between X-ray systems dose settings and patient dose indicators highlights that other factors such as operation protocols and complexity may have more impact in patient dose indicators, which allows a wide margin for optimization. Dose reduction technology together with appropriate training programs will be determinant in the future reduction of patient dose indicators.

From curved spacetime to spacetime-dependent local unitaries over the honeycomb and triangular Quantum Walks.

A discrete-time Quantum Walk (QW) is an operator driving the evolution of a single particle on the lattice, through local unitaries. In a previous paper, we showed that QWs over the honeycomb and triangular lattices can be used to simulate the Dirac equation. We apply a spacetime coordinate transformation upon the lattice of this QW, and show that it is equivalent to introducing spacetime-dependent local unitaries -whilst keeping the lattice fixed. By exploiting this duality between changes in geometry, and changes in local unitaries, we show that the spacetime-dependent QW simulates the Dirac equation in (2 + 1)-dimensional curved spacetime. Interestingly, the duality crucially relies on the non linear-independence of the three preferred directions of the honeycomb and triangular lattices: The same construction would fail for the square lattice. At the practical level, this result opens the possibility to simulate field theories on curved manifolds, via the quantum walk on different kinds of lattices.

Effect of particle size of a mash concentrate on behavior, digestibility, and macroscopic and microscopic integrity of the digestive tract in Holstein bulls fed intensively.

Twenty-four individually housed Holstein bulls (456 ± 6.9 kg of body weight and 292 ± 1.4 d of age) were enrolled in a complete randomized experiment involving four dietary treatments to evaluate the potential effect of mash particle size of diets in finishing beef diets on behavior, digestibility, and macro- and microscopic changes of the digestive tract. The four treatments were all ingredients sieved at 2 mm (HM2), all ingredients sieved at 3 mm (HM3), all ingredients, but corn, sieved at 2 mm and corn at 10 mm (HM210), and all ingredients, but corn, sieved a 3 mm and corn at 10 mm (HM310). For the HM210 and HM310 mashes, corn ground at 10 mm was mixed with the remaining concentrate ingredients ground at 2 or 3 mm, respectively. Concentrate (36% corn, 19% barley, 15% corn gluten feed, 8.4% wheat; 14% crude protein, 3.28 Mcal of ME/kg) consumption was recorded daily and straw consumption weekly. To register behavior, animals were filmed for 24 h on a weekly basis. At day 49 of study nutrient digestibility was estimated. Bulls were slaughtered after 56 d of exposure to treatments. Digestive tract and hepatic lesions were recorded, and tissue samples from the digestive tract collected. Geometric mean particle size was 0.61 ± 0.041, 0.76 ± 0.041, 0.62 ± 0.041, 0.73 ± 0.041 mm, and percentage of particles between 0.5 and 1 mm were 68 ± 2.9, 46 ± 1.7, 46 ± 5.0, and 39 ± 3.3 g/100 g for HM2, HM210, HM3, and HM310, respectively. Performance, total tract digestibility, or digestive tract integrity did not differ when ingredients were ground at 2 or 3 mm. Grinding corn with a hammer mill sieve size of 10 mm reduced feed efficiency and decreased total tract apparent dry matter, and organic matter digestibility compared with treatments from which all ingredients were ground at 2 or 3 mm. Straw intake was greatest and starch digestibility was least in the HM210 treatment. Last, only minor differences among treatments in rumen wall color, rumen papillae fusion, and histological conformation were observed. In summary, to improve feed efficiency, grinding corn at 10 mm is not recommended. In the present study, grinding procedure did not have a great effect on behavior and/or digestive tract health; however, under commercial conditions (group housing), grinding procedures that cause small mean particle sizes or particle size heterogeneity may increase the risk to suffer digestive tract lesions.

Development and implementation of virtual instrumentation based on LabView applied to compression ignition engines operated with diesel-biodiesel blends.

This work shows the implementation and development of a set of virtual instruments focused on recording the physical parameters of a compression ignition engine that operates with diesel-biodiesel, 95% diesel and 5% soybean biodiesel. The components of the engine are constituted by several individual virtual instruments (VI) with the objective of registering parameters such as temperature (VITM), revolutions per minute (VIMRPM), fuel consumption (VIMFC), emission of gases such as oxygen (VIMO) and rust nitric (VIMNO). As a result of the research, the software development, hardware of each of the VIs is presented using the virtual programming platform Labview 2015®, the calibration of the O2 sensors, NO and the result of the operation of the engine at 850 rpm constant an ambient temperature of 25 ℃, a relative humidity of 40% and an operating temperature at the engine head of 65 ℃, obtain a fuel consumption of 0.0616 l/min and an average emission of O2 10% and for the NO 540 ppm. •Implementation of virtual instrument focused on evaluate the physical parameters of CI engine operate with diesel-biodiesel.•The engine runs at 850 RPM under controlled conditions of 25 ℃ and a 40% RH with B5 mixture.•Engine emissions are constant and stable at 10% Vol. O2 and 540 ppm of NO.

Internal Banding to Reduce Paravalvular Leaks for Open Transcatheter Valve Implantation.

Transcatheter valve implantation has become an alternative to open-heart conventional surgery in high-risk patients. We describe a new surgical technique that allows the implantation of a transcatheter valvular prosthesis through an open surgical approach to prevent the appearance of paravalvular leaks in patients with large native rings.