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1.

CAR T cells are in it [CD]4 the long haul.

Poholek, Amanda C.

Cell ; 185(7): 1112-1114, 2022 03 31.

Artículo en Inglés | MEDLINE | ID: mdl-35364030

2.

Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis.

Zhang, Shiqun; Edwards, Tara N; Chaudhri, Virendra K; Wu, Jianing; Cohen, Jonathan A; Hirai, Toshiro; Rittenhouse, Natalie; Schmitz, Elizabeth G; Zhou, Paul Yifan; McNeil, Benjamin D; Yang, Yi; Koerber, H Richard; Sumpter, Tina L; Poholek, Amanda C; Davis, Brian M; Albers, Kathryn M; Singh, Harinder; Kaplan, Daniel H.

Cell ; 184(8): 2151-2166.e16, 2021 04 15.

Artículo en Inglés | MEDLINE | ID: mdl-33765440

3.

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity.

Vignali, Paolo D A; DePeaux, Kristin; Watson, McLane J; Ye, Chenxian; Ford, B Rhodes; Lontos, Konstantinos; McGaa, Nicole K; Scharping, Nicole E; Menk, Ashley V; Robson, Simon C; Poholek, Amanda C; Rivadeneira, Dayana B; Delgoffe, Greg M.

Nat Immunol ; 24(2): 267-279, 2023 02.

Artículo en Inglés | MEDLINE | ID: mdl-36543958

4.

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion.

Scharping, Nicole E; Rivadeneira, Dayana B; Menk, Ashley V; Vignali, Paolo D A; Ford, B Rhodes; Rittenhouse, Natalie L; Peralta, Ronal; Wang, Yiyang; Wang, Yupeng; DePeaux, Kristin; Poholek, Amanda C; Delgoffe, Greg M.

Nat Immunol ; 22(2): 205-215, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-33398183

5.

To loop or not to loop? CNS-28 is the answer.

Yang, Aaron; Poholek, Amanda C.

Immunity ; 56(5): 895-897, 2023 05 09.

Artículo en Inglés | MEDLINE | ID: mdl-37163987

6.

IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival.

Majumder, Saikat; Amatya, Nilesh; Revu, Shankar; Jawale, Chetan V; Wu, Dongwen; Rittenhouse, Natalie; Menk, Ashley; Kupul, Saran; Du, Fang; Raphael, Itay; Bhattacharjee, Amrita; Siebenlist, Ulrich; Hand, Timothy W; Delgoffe, Greg M; Poholek, Amanda C; Gaffen, Sarah L; Biswas, Partha S; McGeachy, Mandy J.

Nat Immunol ; 20(5): 534-545, 2019 05.

Artículo en Inglés | MEDLINE | ID: mdl-30962593

7.

Adaptive plasticity of IL-10⁺ and IL-35⁺ T_reg cells cooperatively promotes tumor T cell exhaustion.

Sawant, Deepali V; Yano, Hiroshi; Chikina, Maria; Zhang, Qianxia; Liao, Mengting; Liu, Chang; Callahan, Derrick J; Sun, Zhe; Sun, Tao; Tabib, Tracy; Pennathur, Arjun; Corry, David B; Luketich, James D; Lafyatis, Robert; Chen, Wei; Poholek, Amanda C; Bruno, Tullia C; Workman, Creg J; Vignali, Dario A A.

Nat Immunol ; 20(6): 724-735, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30936494

8.

MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23.

Mikami, Yohei; Philips, Rachael L; Sciumè, Giuseppe; Petermann, Franziska; Meylan, Françoise; Nagashima, Hiroyuki; Yao, Chen; Davis, Fred P; Brooks, Stephen R; Sun, Hong-Wei; Takahashi, Hayato; Poholek, Amanda C; Shih, Han-Yu; Afzali, Behdad; Muljo, Stefan A; Hafner, Markus; Kanno, Yuka; O'Shea, John J.

Immunity ; 54(3): 514-525.e6, 2021 03 09.

Artículo en Inglés | MEDLINE | ID: mdl-33657395

9.

SLIDE: Significant Latent Factor Interaction Discovery and Exploration across biological domains.

Rahimikollu, Javad; Xiao, Hanxi; Rosengart, AnnaElaine; Rosen, Aaron B I; Tabib, Tracy; Zdinak, Paul M; He, Kun; Bing, Xin; Bunea, Florentina; Wegkamp, Marten; Poholek, Amanda C; Joglekar, Alok V; Lafyatis, Robert A; Das, Jishnu.

Nat Methods ; 21(5): 835-845, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38374265

10.

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid.

Watson, McLane J; Vignali, Paolo D A; Mullett, Steven J; Overacre-Delgoffe, Abigail E; Peralta, Ronal M; Grebinoski, Stephanie; Menk, Ashley V; Rittenhouse, Natalie L; DePeaux, Kristin; Whetstone, Ryan D; Vignali, Dario A A; Hand, Timothy W; Poholek, Amanda C; Morrison, Brett M; Rothstein, Jeffrey D; Wendell, Stacy G; Delgoffe, Greg M.

Nature ; 591(7851): 645-651, 2021 03.

Artículo en Inglés | MEDLINE | ID: mdl-33589820

11.

Innovative super-resolution in spatial transcriptomics: a transformer model exploiting histology images and spatial gene expression.

Zhao, Chongyue; Xu, Zhongli; Wang, Xinjun; Tao, Shiyue; MacDonald, William A; He, Kun; Poholek, Amanda C; Chen, Kong; Huang, Heng; Chen, Wei.

Brief Bioinform ; 25(2)2024 Jan 22.

Artículo en Inglés | MEDLINE | ID: mdl-38436557

12.

Regulation and Immunotherapeutic Targeting of the Epigenome in Exhausted CD8 T Cell Responses.

Ford, B Rhodes; Poholek, Amanda C.

J Immunol ; 210(7): 869-879, 2023 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-36947818

13.

Cubilin-, megalin-, and Dab2-dependent transcription revealed by CRISPR/Cas9 knockout in kidney proximal tubule cells.

Long, Kimberly R; Rbaibi, Youssef; Bondi, Corry D; Ford, B Rhodes; Poholek, Amanda C; Boyd-Shiwarski, Cary R; Tan, Roderick J; Locker, Joseph D; Weisz, Ora A.

Am J Physiol Renal Physiol ; 322(1): F14-F26, 2022 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-34747197

14.

Shear stress and oxygen availability drive differential changes in opossum kidney proximal tubule cell metabolism and endocytosis.

Ren, Qidong; Gliozzi, Megan L; Rittenhouse, Natalie L; Edmunds, Lia R; Rbaibi, Youssef; Locker, Joseph D; Poholek, Amanda C; Jurczak, Michael J; Baty, Catherine J; Weisz, Ora A.

Traffic ; 20(6): 448-459, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30989771

15.

Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation.

Marks, Benjamin R; Nowyhed, Heba N; Choi, Jin-Young; Poholek, Amanda C; Odegard, Jared M; Flavell, Richard A; Craft, Joe.

Nat Immunol ; 10(10): 1125-32, 2009 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-19734905

16.

Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection.

Marshall, Heather D; Chandele, Anmol; Jung, Yong Woo; Meng, Hailong; Poholek, Amanda C; Parish, Ian A; Rutishauser, Rachel; Cui, Weiguo; Kleinstein, Steven H; Craft, Joe; Kaech, Susan M.

Immunity ; 35(4): 633-46, 2011 Oct 28.

Artículo en Inglés | MEDLINE | ID: mdl-22018471

17.

Transcriptional and epigenetic networks of helper T and innate lymphoid cells.

Shih, Han-Yu; Sciumè, Giuseppe; Poholek, Amanda C; Vahedi, Golnaz; Hirahara, Kiyoshi; Villarino, Alejandro V; Bonelli, Michael; Bosselut, Remy; Kanno, Yuka; Muljo, Stefan A; O'Shea, John J.

Immunol Rev ; 261(1): 23-49, 2014 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-25123275

18.

CCAAT/Enhancer-binding protein ß promotes pathogenesis of EAE.

Simpson-Abelson, Michelle R; Hernandez-Mir, Gerard; Childs, Erin E; Cruz, J Agustin; Poholek, Amanda C; Chattopadhyay, Ansuman; Gaffen, Sarah L; McGeachy, Mandy J.

Cytokine ; 92: 24-32, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-28088614

19.

B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen.

Weinstein, Jason S; Bertino, Sarah A; Hernandez, Sairy G; Poholek, Amanda C; Teplitzky, Taylor B; Nowyhed, Heba N; Craft, Joe.

J Immunol ; 192(7): 3166-79, 2014 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-24610013

20.

Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program.

Nakayamada, Shingo; Poholek, Amanda C; Lu, Kristina T; Takahashi, Hayato; Kato, Masanari; Iwata, Shigeru; Hirahara, Kiyoshi; Cannons, Jennifer L; Schwartzberg, Pamela L; Vahedi, Golnaz; Sun, Hong-Wei; Kanno, Yuka; O'Shea, John J.

J Immunol ; 192(5): 2156-66, 2014 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-24489092

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