RESUMEN
OBJECTIVE: To observe the effect of Capsule YD on blood hemorheology and the score of blood stasis in patients with MS complicated ACS, and to investigate the clinical effect of Chinese medicine of promoting blood flow on those diseases. METHODS: 63 cases were divided into two groups. Control group was treated with routine methods and YD group with additional YD. The course of treatment was 3 months. Blood hemorheology and the score of blood stasis were observed. RESULTS: Blood viscosity high shear rate, fibrinogen, the index and deformed index of Erythrocyte aggregation before and after treatment in both groups were improved (P < 0.05). And the index of Erythrocyte aggregation in YD group was significantly improved comparing to that in control group (P < 0.05). The symtom of stethalgia, frequency of episode, and blood stasis on tongue, lip and gums were also improved in YD group. The value of blood stasis in YD group was significantly decreased comparing to that in control group. CONCLUSIONS: Capsule YD can improve the angina pectoris and decrease the value of blood stasis in patients with ACS, and also improve their hemorheology. We should presume the Chinese medicine of activating blood circulation to dissipate blood stasis improve the metabolism and treat angina pectoris by improving blood hyperviscosity.
Asunto(s)
Viscosidad Sanguínea/efectos de los fármacos , Enfermedad Coronaria/tratamiento farmacológico , Medicamentos Herbarios Chinos/uso terapéutico , Síndrome Metabólico/tratamiento farmacológico , Fitoterapia , Anciano , Cápsulas , Enfermedad Coronaria/sangre , Enfermedad Coronaria/etiología , Combinación de Medicamentos , Medicamentos Herbarios Chinos/química , Medicamentos Herbarios Chinos/farmacología , Agregación Eritrocitaria/efectos de los fármacos , Deformación Eritrocítica/efectos de los fármacos , Femenino , Hemorreología , Humanos , Masculino , Síndrome Metabólico/sangre , Síndrome Metabólico/complicaciones , Persona de Mediana Edad , Plantas Medicinales/química , Resultado del TratamientoRESUMEN
OBJECTIVE: To observe the influence of Xinmaitong capsule (XMT) on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome. METHOD: 63 cases were divided by randomized, contrastive assigned to XMT group (n = 31) and control group (n = 32). The serum levels of MMP-9 and hs-CRP before and after treatment in 12 weeks were detected. RESULT: After treatment, the serum levels of MMP-9 in control group had no changed and the levels of hs-CRP reduced. The serum levels of MMP-9 and hs-CRP in XMT group had significantly decreased. The serum levels of MMP-9 and hs-CRP had positive correlation, but had no correlation to levels of serum lipids. CONCLUSION: XMT decreased breakdown of matrix collagen, and inflammatory reaction in the patients of ACS, which may have effect on plaque stabilization.