1.
Chem Commun (Camb)
; 60(56): 7168-7171, 2024 Jul 09.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38904189
RESUMEN
We report a chemoselective and site-selective precision engineering of lysine in proteases. The mild and physiological reaction conditions keep their auto-degradation under control. Furthermore, it enables single-site ordered immobilization, enhancing protein digestion and peptide mapping efficiency.