1.
Int J Gynecol Cancer
; 33(9): 1482-1484, 2023 09 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37268312
2.
Gynecol Oncol Rep
; 48: 101215, 2023 Aug.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37334322
RESUMEN
â¢This is the first report of a germline DICER1-associated Sertoli-Leydig cell tumor (SLCT) diagnosed in pregnancy.â¢SLCT is linked to DICER1 pathogenic variants, but little is known about management of DICER1-associated SLCT.â¢There is an extended risk for metachronous SLCT in patients with germline DICER1 pathogenic variants who retain an ovary.â¢Prophylactic contralateral salpingo-oophorectomy may be offered with shared decision making to patients with inherited SLCT.â¢Genetic testing for DICER1 should be offered to all patients with moderately or poorly differentiated SLCT.