Pancreatic PEComa, a not so uncommon neoplasm? Systematic review and therapeutic update. / PEComa pancreático ¿una neoplasia no tan infrecuente? Revisión sistemática y actualización clínico-terapéutica.

Pancreatic PEComas are extremely rare neoplasms with malignant potential, which mostly affect middle-aged women and are characterized by presenting melanocytic and myogenic markers in immunohistochemical analysis. There are no symptoms or pathognomonic imaging tests, so the diagnosis is established with the analysis of the surgical specimen or the FNA obtained with preoperative endoscopic ultrasound. The mean treatment consists on radical excision, adapting the intervention to the location of the tumor. To date, 34 cases have been described; however, more than 80% of them have been reported in the last decade, which suggests that it is a more frequent pathology than expected. A new case of pancreatic PEComa is reported and a systematic review of the literature is carried out according to the PRISMA guidelines with the aim of divulge this pathology, deepening its knowledge and updating its management.

[Diabetic mastopathy. Features in four patients]. / Mastopatía diabética. Estudio de 4 pacientes.

Diabetic mastopathy is a clinicopathologic entity that represents less than 1% of benign breast disease and is mainly related to type 1 diabetes. The pathogenesis is unknown but the most convincing hypothesis postulates extracellular collagen deposit and predominantly B-cell inflammation with autoimmune response. The clinical, radiological and pathological features of four patients with diabetic mastopathy are presented.