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1.
Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia.
Cancer Sci
; 115(3): 963-973, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38226414
2.
Discovery of 9H-pyrimido[4,5-b]indole derivatives as dual RET/TRKA inhibitors.
Bioorg Med Chem
; 106: 117749, 2024 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38744018
3.
The Set1 Histone H3K4 Methyltransferase Contributes to Azole Susceptibility in a Species-Specific Manner by Differentially Altering the Expression of Drug Efflux Pumps and the Ergosterol Gene Pathway.
Antimicrob Agents Chemother
; 66(5): e0225021, 2022 05 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-35471041
4.
Imaging Methods for the Assessment of a Complex Hydrogel as an Ocular Drug Delivery System for Glaucoma Treatment: Opportunities and Challenges in Preclinical Evaluation.
Mol Pharm
; 19(3): 733-748, 2022 03 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35179892
5.
A Lewis Base Catalysis Approach for the Photoredox Activation of Boronic Acids and Esters.
Angew Chem Int Ed Engl
; 56(47): 15136-15140, 2017 11 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29024307
6.
Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules.
RSC Med Chem
; 15(2): 399-415, 2024 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38389874
7.
Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma.
Mol Cancer Ther
; 23(3): 316-329, 2024 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37816504
8.
In vitro laser scanning confocal microscopy and unsupervised segmentation: Quantification of cytosolic calcium and RNA distribution in hypoxic neurons.
Annu Int Conf IEEE Eng Med Biol Soc
; 2023: 1-4, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38083364
9.
A deep learning approach for automation in neurite tracing and cell size estimation from differential contrast images under healthy and hypoxic condition.
Annu Int Conf IEEE Eng Med Biol Soc
; 2023: 1-4, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38083674
10.
Expanding the toolkit for genetic manipulation and discovery in Candida species using a CRISPR ribonucleoprotein-based approach.
bioRxiv
; 2023 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37398038
11.
Non-prophylactic resveratrol-mediated protection of neurite integrity under chronic hypoxia is associated with reduction of Cav1.2 channel expression and calcium overloading.
Neurochem Int
; 164: 105466, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36587745
12.
An expanded toolkit of drug resistance cassettes for Candida glabrata, Candida auris, and Candida albicans leads to new insights into the ergosterol pathway.
mSphere
; 8(6): e0031123, 2023 Dec 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37929964
13.
FLT3 inhibitors for acute myeloid leukemia: successes, defeats, and emerging paradigms.
RSC Med Chem
; 13(7): 798-816, 2022 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35923716
14.
Targeting a Novel G-Quadruplex in the CARD11 Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group.
Genes (Basel)
; 13(7)2022 06 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35885931
15.
Pyrazoloadenine Inhibitors of the RET Lung Cancer Oncoprotein Discovered by a Fragment Optimization Approach.
ChemMedChem
; 16(10): 1605-1608, 2021 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33559353
16.
FDA approved L-type channel blocker Nifedipine reduces cell death in hypoxic A549 cells through modulation of mitochondrial calcium and superoxide generation.
Free Radic Biol Med
; 177: 189-200, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34666149
17.
Discovery and biological evaluation of phthalazines as novel non-kinase TGFß pathway inhibitors.
Eur J Med Chem
; 223: 113660, 2021 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34246853
18.
Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
J Med Chem
; 64(16): 11747-11773, 2021 08 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-34402300
19.
The Exploration of Chirality for Improved Druggability within the Human Kinome.
J Med Chem
; 63(2): 441-469, 2020 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31550151
20.
Treatment of Male Breast Cancer by Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade and Response Prediction Using Novel Optical Tomography Imaging: A Case Report.
Cureus
; 9(7): e1481, 2017 Jul 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-28944120