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1.

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.

Jeltsch, Katharina M; Hu, Desheng; Brenner, Sven; Zöller, Jessica; Heinz, Gitta A; Nagel, Daniel; Vogel, Katharina U; Rehage, Nina; Warth, Sebastian C; Edelmann, Stephanie L; Gloury, Renee; Martin, Nina; Lohs, Claudia; Lech, Maciej; Stehklein, Jenny E; Geerlof, Arie; Kremmer, Elisabeth; Weber, Achim; Anders, Hans-Joachim; Schmitz, Ingo; Schmidt-Supprian, Marc; Fu, Mingui; Holtmann, Helmut; Krappmann, Daniel; Ruland, Jürgen; Kallies, Axel; Heikenwalder, Mathias; Heissmeyer, Vigo.

Nat Immunol ; 15(11): 1079-89, 2014 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-25282160

2.

Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.

Schmidt, Henrik; Raj, Timsse; O'Neill, Thomas J; Muschaweckh, Andreas; Giesert, Florian; Negraschus, Arlinda; Hoefig, Kai P; Behrens, Gesine; Esser, Lena; Baumann, Christina; Feederle, Regina; Plaza-Sirvent, Carlos; Geerlof, Arie; Gewies, Andreas; Isay, Sophie E; Ruland, Jürgen; Schmitz, Ingo; Wurst, Wolfgang; Korn, Thomas; Krappmann, Daniel; Heissmeyer, Vigo.

Proc Natl Acad Sci U S A ; 120(48): e2309205120, 2023 Nov 28.

Artículo en Inglés | MEDLINE | ID: mdl-37988467

3.

Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells.

Dwyer, Jennifer R; Racine, Jeremy J; Chapman, Harold D; Quinlan, Anna; Presa, Maximiliano; Stafford, Grace A; Schmitz, Ingo; Serreze, David V.

J Immunol ; 209(2): 227-237, 2022 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-35760520

4.

Emission Spectroscopy-Based Sensor System to Correlate the In-Cylinder Combustion Temperature of a Diesel Engine to NO_x Emissions.

Wultschner, Jürgen; Schmitz, Ingo; Révidat, Stephan; Ullrich, Johannes; Seeger, Thomas.

Sensors (Basel) ; 24(8)2024 Apr 11.

Artículo en Inglés | MEDLINE | ID: mdl-38676076

5.

Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1ß Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients.

Wacker, Max; Ball, Anna; Beer, Hans-Dietmar; Schmitz, Ingo; Borucki, Katrin; Azizzadeh, Faranak; Scherner, Maximilian; Awad, George; Wippermann, Jens; Veluswamy, Priya.

Int J Mol Sci ; 24(8)2023 Apr 13.

Artículo en Inglés | MEDLINE | ID: mdl-37108367

6.

Gadd45 Proteins in Immunity 2.0.

Schmitz, Ingo.

Adv Exp Med Biol ; 1360: 69-86, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35505163

7.

Regulating T-cell differentiation through the polyamine spermidine.

Carriche, Guilhermina M; Almeida, Luís; Stüve, Philipp; Velasquez, Lis; Dhillon-LaBrooy, Ayesha; Roy, Urmi; Lindenberg, Marc; Strowig, Till; Plaza-Sirvent, Carlos; Schmitz, Ingo; Lochner, Matthias; Simon, Anna Katharina; Sparwasser, Tim.

J Allergy Clin Immunol ; 147(1): 335-348.e11, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-32407834

8.

Type of PaperY192 within the SH2 Domain of Lck Regulates TCR Signaling Downstream of PLC-Î³1 and Thymic Selection.

Kästle, Matthias; Merten, Camilla; Hartig, Roland; Plaza-Sirvent, Carlos; Schmitz, Ingo; Bommhardt, Ursula; Schraven, Burkhart; Simeoni, Luca.

Int J Mol Sci ; 23(13)2022 Jun 30.

Artículo en Inglés | MEDLINE | ID: mdl-35806279

9.

The NF-κB transcription factor c-Rel controls host defense against Citrobacter rodentium.

Luu, Maik; Romero, Rossana; Bazant, Jasmin; Abass, Elfadil; Hartmann, Sabrina; Leister, Hanna; Fischer, Florence; Mahdavi, Rouzbeh; Plaza-Sirvent, Carlos; Schmitz, Ingo; Steinhoff, Ulrich; Visekruna, Alexander.

Eur J Immunol ; 50(2): 292-294, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31724737

10.

IκB(NS) protein mediates regulatory T cell development via induction of the Foxp3 transcription factor.

Schuster, Marc; Glauben, Rainer; Plaza-Sirvent, Carlos; Schreiber, Lisa; Annemann, Michaela; Floess, Stefan; Kühl, Anja A; Clayton, Linda K; Sparwasser, Tim; Schulze-Osthoff, Klaus; Pfeffer, Klaus; Huehn, Jochen; Siegmund, Britta; Schmitz, Ingo.

Immunity ; 37(6): 998-1008, 2012 Dec 14.

Artículo en Inglés | MEDLINE | ID: mdl-23200824

11.

Essential role of IκB_NS for in vivo CD4⁺ T-cell activation, proliferation, and Th1-cell differentiation during Listeria monocytogenes infection in mice.

Frentzel, Sarah; Katsoulis-Dimitriou, Konstantinos; Jeron, Andreas; Schmitz, Ingo; Bruder, Dunja.

Eur J Immunol ; 49(9): 1391-1398, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-31049948

12.

A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8⁺ T Cells in NOD Mice.

Presa, Maximiliano; Racine, Jeremy J; Dwyer, Jennifer R; Lamont, Deanna J; Ratiu, Jeremy J; Sarsani, Vishal Kumar; Chen, Yi-Guang; Geurts, Aron; Schmitz, Ingo; Stearns, Timothy; Allocco, Jennifer; Chapman, Harold D; Serreze, David V.

J Immunol ; 201(7): 1907-1917, 2018 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-30127089

13.

Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of K_v1.3 potassium channels, AKT and ERK1/2 signaling.

Lowinus, Theresa; Heidel, Florian H; Bose, Tanima; Nimmagadda, Subbaiah Chary; Schnöder, Tina; Cammann, Clemens; Schmitz, Ingo; Seifert, Ulrike; Fischer, Thomas; Schraven, Burkhart; Bommhardt, Ursula.

Cell Commun Signal ; 17(1): 5, 2019 01 16.

Artículo en Inglés | MEDLINE | ID: mdl-30651113

14.

c-REL and IκB_NS Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors.

Schuster, Marc; Plaza-Sirvent, Carlos; Matthies, Anne-Marie; Heise, Ulrike; Jeron, Andreas; Bruder, Dunja; Visekruna, Alexander; Huehn, Jochen; Schmitz, Ingo.

J Immunol ; 199(3): 920-930, 2017 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-28652399

15.

Humoral and cellular immune responses to repeated SARS-CoV-2 infection and vaccination in an individual living with HIV.

Simsek, Agit; Bessen, Clara; Meister, Toni L; Urlaub, Doris; Skaletz-Rorowski, Adriane; Brockmeyer, Norbert H; Overheu, Oliver; Reinacher-Schick, Anke; Faissner, Simon; Watzl, Carsten; Pfaender, Stephanie; Schmitz, Ingo; Potthoff, Anja; Plaza-Sirvent, Carlos.

J Eur Acad Dermatol Venereol ; 37(7): e825-e827, 2023 07.

Artículo en Inglés | MEDLINE | ID: mdl-36912717

16.

IκBNS regulates murine Th17 differentiation during gut inflammation and infection.

Annemann, Michaela; Wang, Zuobai; Plaza-Sirvent, Carlos; Glauben, Rainer; Schuster, Marc; Ewald Sander, Frida; Mamareli, Panagiota; Kühl, Anja A; Siegmund, Britta; Lochner, Matthias; Schmitz, Ingo.

J Immunol ; 194(6): 2888-98, 2015 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-25694610

17.

Autophagy in T-cell development, activation and differentiation.

Bronietzki, Alisha W; Schuster, Marc; Schmitz, Ingo.

Immunol Cell Biol ; 93(1): 25-34, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25287445

18.

IκBÎ¶ is a transcriptional key regulator of CCL2/MCP-1.

Hildebrand, Dominic G; Alexander, Eva; Hörber, Sebastian; Lehle, Simon; Obermayer, Kerstin; Münck, Niels-Arne; Rothfuss, Oliver; Frick, Julia-Stefanie; Morimatsu, Masami; Schmitz, Ingo; Roth, Johannes; Ehrchen, Jan M; Essmann, Frank; Schulze-Osthoff, Klaus.

J Immunol ; 190(9): 4812-20, 2013 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-23547114

19.

Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.

Franco, Rodrigo; Bortner, Carl D; Schmitz, Ingo; Cidlowski, John A.

Apoptosis ; 19(1): 117-34, 2014 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-24146141

20.

Cellular-FLIP, Raji isoform (c-FLIP R) modulates cell death induction upon T-cell activation and infection.

Telieps, Tanja; Ewald, Frida; Gereke, Marcus; Annemann, Michaela; Rauter, Yvonne; Schuster, Marc; Ueffing, Nana; von Smolinski, Dorthe; Gruber, Achim D; Bruder, Dunja; Schmitz, Ingo.

Eur J Immunol ; 43(6): 1499-510, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23505065

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