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1.

The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5.

Polat, Onur K; Isaeva, Elena; Sudhini, Yashwanth R; Knott, Brenna; Zhu, Ke; Noben, Manuel; Suresh Kumar, Varsha; Endlich, Nicole; Mangos, Steve; Reddy, Tejasree Vallapu; Samelko, Beata; Wei, Changli; Altintas, Mehmet M; Dryer, Stuart E; Sever, Sanja; Staruschenko, Alexander; Reiser, Jochen.

Kidney Int ; 103(6): 1056-1062, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-36750145

2.

Soluble Urokinase Receptor and Acute Kidney Injury.

Hayek, Salim S; Leaf, David E; Samman Tahhan, Ayman; Raad, Mohamad; Sharma, Shreyak; Waikar, Sushrut S; Sever, Sanja; Camacho, Alex; Wang, Xuexiang; Dande, Ranadheer R; Ibrahim, Nasrien E; Baron, Rebecca M; Altintas, Mehmet M; Wei, Changli; Sheikh-Hamad, David; Pan, Jenny S-C; Holliday, Michael W; Januzzi, James L; Weisbord, Steven D; Quyyumi, Arshed A; Reiser, Jochen.

N Engl J Med ; 382(5): 416-426, 2020 01 30.

Artículo en Inglés | MEDLINE | ID: mdl-31995687

3.

Synaptotagmin-mediated vesicle fusion regulates cell migration.

Colvin, Richard A; Means, Terry K; Diefenbach, Thomas J; Moita, Luis F; Friday, Robert P; Sever, Sanja; Campanella, Gabriele S V; Abrazinski, Tabitha; Manice, Lindsay A; Moita, Catarina; Andrews, Norma W; Wu, Dianqing; Hacohen, Nir; Luster, Andrew D.

Nat Immunol ; 11(6): 495-502, 2010 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-20473299

4.

Role of actin cytoskeleton in podocytes.

Sever, Sanja.

Pediatr Nephrol ; 36(9): 2607-2614, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-33188449

5.

Actin dynamics at focal adhesions: a common endpoint and putative therapeutic target for proteinuric kidney diseases.

Sever, Sanja; Schiffer, Mario.

Kidney Int ; 93(6): 1298-1307, 2018 06.

Artículo en Inglés | MEDLINE | ID: mdl-29678354

6.

Soluble Urokinase Receptor and Chronic Kidney Disease.

Hayek, Salim S; Sever, Sanja; Ko, Yi-An; Trachtman, Howard; Awad, Mosaab; Wadhwani, Shikha; Altintas, Mehmet M; Wei, Changli; Hotton, Anna L; French, Audrey L; Sperling, Laurence S; Lerakis, Stamatios; Quyyumi, Arshed A; Reiser, Jochen.

N Engl J Med ; 373(20): 1916-25, 2015 Nov 12.

Artículo en Inglés | MEDLINE | ID: mdl-26539835

7.

Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation.

Gu, Changkyu; Lee, Ha Won; Garborcauskas, Garrett; Reiser, Jochen; Gupta, Vineet; Sever, Sanja.

J Am Soc Nephrol ; 28(2): 446-451, 2017 02.

Artículo en Inglés | MEDLINE | ID: mdl-27432739

8.

Regulation of dynamin oligomerization in cells: the role of dynamin-actin interactions and its GTPase activity.

Gu, Changkyu; Chang, Joann; Shchedrina, Valentina A; Pham, Vincent A; Hartwig, John H; Suphamungmee, Worawit; Lehman, William; Hyman, Bradley T; Bacskai, Brian J; Sever, Sanja.

Traffic ; 15(8): 819-38, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24891099

9.

A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules.

Lee, Ha Won; Khan, Samia Q; Faridi, Mohd Hafeez; Wei, Changli; Tardi, Nicholas J; Altintas, Mehmet M; Elshabrawy, Hatem A; Mangos, Steve; Quick, Kevin L; Sever, Sanja; Reiser, Jochen; Gupta, Vineet.

J Am Soc Nephrol ; 26(11): 2741-52, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-25858967

10.

Dynamin rings: not just for fission.

Sever, Sanja; Chang, Joann; Gu, Changkyu.

Traffic ; 14(12): 1194-9, 2013 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-23980695

11.

Reduction of proteinuria through podocyte alkalinization.

Altintas, Mehmet M; Moriwaki, Kumiko; Wei, Changli; Möller, Clemens C; Flesche, Jan; Li, Jing; Yaddanapudi, Suma; Faridi, Mohd Hafeez; Gödel, Markus; Huber, Tobias B; Preston, Richard A; Jiang, Jean X; Kerjaschki, Dontscho; Sever, Sanja; Reiser, Jochen.

J Biol Chem ; 289(25): 17454-67, 2014 Jun 20.

Artículo en Inglés | MEDLINE | ID: mdl-24817115

12.

Podocyte biology and pathogenesis of kidney disease.

Reiser, Jochen; Sever, Sanja.

Annu Rev Med ; 64: 357-66, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23190150

13.

Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.

Kistler, Andreas D; Singh, Geetika; Altintas, Mehmet M; Yu, Hao; Fernandez, Isabel C; Gu, Changkyu; Wilson, Cory; Srivastava, Sandeep Kumar; Dietrich, Alexander; Walz, Katherina; Kerjaschki, Dontscho; Ruiz, Phillip; Dryer, Stuart; Sever, Sanja; Dinda, Amit K; Faul, Christian; Reiser, Jochen.

J Biol Chem ; 288(51): 36598-609, 2013 Dec 20.

Artículo en Inglés | MEDLINE | ID: mdl-24194522

14.

Direct dynamin-actin interactions regulate the actin cytoskeleton.

Gu, Changkyu; Yaddanapudi, Suma; Weins, Astrid; Osborn, Teresia; Reiser, Jochen; Pollak, Martin; Hartwig, John; Sever, Sanja.

EMBO J ; 29(21): 3593-606, 2010 Nov 03.

Artículo en Inglés | MEDLINE | ID: mdl-20935625

15.

Recessive variants in the intergenic NOS1AP-C1orf226 locus cause monogenic kidney disease responsive to anti-proteinuric treatment.

Buerger, Florian; Salmanullah, Daanya; Liang, Lorrin; Gauntner, Victoria; Krueger, Kavita; Qi, Maggie; Sharma, Vineeta; Rubin, Alexander; Ball, David; Lemberg, Katharina; Saida, Ken; Merz, Lea Maria; Sever, Sanja; Issac, Biju; Sun, Liang; Guerrero-Castillo, Sergio; Gomez, Alexis C; McNulty, Michelle T; Sampson, Matthew G; Al-Hamed, Mohamed H; Saleh, Mohammed M; Shalaby, Mohamed; Kari, Jameela; Fawcett, James P; Hildebrandt, Friedhelm; Majmundar, Amar J.

medRxiv ; 2024 Mar 21.

Artículo en Inglés | MEDLINE | ID: mdl-38562757

16.

Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis.

Conery, Andrew R; Sever, Sanja; Harlow, Ed.

Proc Natl Acad Sci U S A ; 107(35): 15461-6, 2010 Aug 31.

Artículo en Inglés | MEDLINE | ID: mdl-20713695

17.

The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease.

Zhu, Ke; Mukherjee, Kamalika; Wei, Changli; Hayek, Salim S; Collins, Agnieszka; Gu, Changkyu; Corapi, Kristin; Altintas, Mehmet M; Wang, Yong; Waikar, Sushrut S; Bianco, Antonio C; Koch, Alexander; Tacke, Frank; Reiser, Jochen; Sever, Sanja.

Sci Transl Med ; 15(714): eabq6492, 2023 09 20.

Artículo en Inglés | MEDLINE | ID: mdl-37729431

18.

Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury.

Mukherjee, Kamalika; Gu, Changkyu; Collins, Agnieszka; Mettlen, Marcel; Samelko, Beata; Altintas, Mehmet M; Sudhini, Yashwanth R; Wang, Xuexiang; Bouley, Richard; Brown, Dennis; Pedro, Bradley P; Bane, Susan L; Gupta, Vineet; Brinkkoetter, Paul T; Hagmann, Henning; Reiser, Jochen; Sever, Sanja.

Nat Commun ; 13(1): 2422, 2022 05 03.

Artículo en Inglés | MEDLINE | ID: mdl-35504916

19.

CD2AP, dendrin, and cathepsin L in the kidney.

Sever, Sanja; Reiser, Jochen.

Am J Pathol ; 185(11): 3129-30, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26506476

20.

Dynamin and endocytosis.