Detalles de la búsqueda
1.
Whole-genome analysis of genetic recombination of hepatitis delta virus: molecular domain in delta antigen determining trans-activating efficiency.
J Gen Virol
; 96(12): 3460-3469, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26407543
2.
Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists.
Bioorg Med Chem Lett
; 24(1): 156-60, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24332491
3.
Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists.
Bioorg Med Chem Lett
; 24(4): 1133-7, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24440299
4.
Discovery and optimization of arylsulfonyl 3-(pyridin-2-yloxy)anilines as novel GPR119 agonists.
Bioorg Med Chem Lett
; 23(12): 3609-13, 2013 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23648181
5.
A comparison of the ultrastructure and composition of fruits' cuticular wax from the wild-type 'Newhall' navel orange (Citrus sinensis [L.] Osbeck cv. Newhall) and its glossy mutant.
Plant Cell Rep
; 31(12): 2239-46, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22892682
6.
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Proc Natl Acad Sci U S A
; 106(24): 9820-5, 2009 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19443683
7.
Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors.
Bioorg Med Chem Lett
; 21(12): 3774-9, 2011 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21565497
8.
Discovery of pyrrolopyridazines as novel DGAT1 inhibitors.
Bioorg Med Chem Lett
; 20(20): 6030-3, 2010 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20833038
9.
Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis.
Dev Cell
; 2(6): 713-20, 2002 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12062084
10.
The crystal structure of PCSK9: a regulator of plasma LDL-cholesterol.
Structure
; 15(5): 545-52, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17502100
11.
Structural Pattern Differences in Unbranched Rod-like RNA of Hepatitis Delta Virus affect RNA Editing.
Viruses
; 11(10)2019 10 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31614652
12.
Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
Bioorg Med Chem
; 16(19): 8922-31, 2008 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18789704
13.
Improvement of start-up and nitrogen removal of the anammox process in reactors inoculated with conventional activated sludge using biofilm carrier materials.
Environ Technol
; 39(1): 59-67, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-28278777
14.
Analyses of a whole-genome inter-clade recombination map of hepatitis delta virus suggest a host polymerase-driven and viral RNA structure-promoted template-switching mechanism for viral RNA recombination.
Oncotarget
; 8(37): 60841-60859, 2017 Sep 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-28977829
15.
The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
Nat Med
; 23(10): 1215-1219, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28846098
16.
Reduced genetic distance and high replication levels increase the RNA recombination rate of hepatitis delta virus.
Virus Res
; 195: 79-85, 2015 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25172581
17.
Trefoil Factor 3 (TFF3) Is Regulated by Food Intake, Improves Glucose Tolerance and Induces Mucinous Metaplasia.
PLoS One
; 10(6): e0126924, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26083576
18.
Advancing therapeutic discovery through phenotypic screening of the extracellular proteome using hydrodynamic intravascular injection.
Expert Opin Ther Targets
; 18(11): 1253-64, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25287216
19.
Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodents.
J Med Chem
; 57(8): 3464-83, 2014 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-24670009
20.
A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents.
PLoS One
; 7(10): e46300, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23056280