1.
Org Biomol Chem
; 14(24): 5477-80, 2016 Jun 28.
Artículo
en Inglés
| MEDLINE
| ID: mdl-26419921
RESUMEN
A method for the [2 + 2] cycloaddition of aryl ketenes and alkenes is presented. The process involves the in situ generation of a ketene in the presence of a Lewis acid. The utility of products is demonstrated towards the synthesis of a common scaffold found in several natural product families.