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1.
Novel bone-targeted parathyroid hormone-related peptide antagonists inhibit breast cancer bone metastases.
Anticancer Drugs
; 32(4): 365-375, 2021 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33595947
2.
Novel Quantification of Extracellular Vesicles with Unaltered Surface Membranes Using an Internalized Oligonucleotide Tracer and Applied Pharmacokinetic Multiple Compartment Modeling.
Pharm Res
; 38(10): 1677-1695, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-34671921
3.
Simultaneous Pharmacokinetic Analysis of Nitrate and its Reduced Metabolite, Nitrite, Following Ingestion of Inorganic Nitrate in a Mixed Patient Population.
Pharm Res
; 37(12): 235, 2020 Nov 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33140122
4.
Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs.
Mol Pharmacol
; 96(2): 272-296, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31221824
5.
Development of a Semimechanistic Pharmacokinetic-Pharmacodynamic Model Describing Dextroamphetamine Exposure and Striatal Dopamine Response in Rats and Nonhuman Primates following a Single Dose of Dextroamphetamine.
J Pharmacol Exp Ther
; 369(1): 107-120, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30733244
6.
Development of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain Concentrations.
Drug Metab Dispos
; 44(5): 624-33, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26916207
7.
Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M1 agonists.
Bioorg Med Chem Lett
; 25(19): 4158-63, 2015 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26299349
8.
Prediction of brain clozapine and norclozapine concentrations in humans from a scaled pharmacokinetic model for rat brain and plasma pharmacokinetics.
J Transl Med
; 12: 203, 2014 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25142323
9.
Bridging population pharmacokinetic and semimechanistic absorption modeling of APX3330.
CPT Pharmacometrics Syst Pharmacol
; 13(1): 106-117, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37884051
10.
Screening and identification of glyceollins and their metabolites by electrospray ionization tandem mass spectrometry with precursor ion scanning.
Anal Chem
; 85(3): 1727-33, 2013 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-23294002
11.
GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models.
Bioorg Med Chem Lett
; 23(23): 6459-62, 2013 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24119554
12.
GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy.
Bioorg Med Chem Lett
; 23(23): 6463-6, 2013 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24140446
13.
Characterization of the Stereoselective Disposition of Bupropion and Its Metabolites in Rat Plasma and Brain.
Eur J Drug Metab Pharmacokinet
; 48(2): 171-187, 2023 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-36823342
14.
Microdialysis evaluation of clozapine and N-desmethylclozapine pharmacokinetics in rat brain.
Drug Metab Dispos
; 40(10): 1909-16, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22736307
15.
Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Patch Infected by SARS-CoV-2.
Viruses
; 14(3)2022 03 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35337012
16.
Population model analysis of chiral inversion and degradation of bupropion enantiomers, and application to enantiomer specific fraction unbound determination in rat plasma and brain.
J Pharm Biomed Anal
; 195: 113872, 2021 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-33388643
17.
Application of machine learning to predict reduction in total PANSS score and enrich enrollment in schizophrenia clinical trials.
Clin Transl Sci
; 14(5): 1864-1874, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33939284
18.
Inhibiting Fatty Acid Synthase with Omeprazole to Improve Efficacy of Neoadjuvant Chemotherapy in Patients with Operable TNBC.
Clin Cancer Res
; 27(21): 5810-5817, 2021 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34400413
19.
Comparison of In Vitro Stereoselective Metabolism of Bupropion in Human, Monkey, Rat, and Mouse Liver Microsomes.
Eur J Drug Metab Pharmacokinet
; 44(2): 261-274, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30298475
20.
Development of a non-human primate model to support CNS translational research: Demonstration with D-amphetamine exposure and dopamine response.
J Neurosci Methods
; 317: 71-81, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30768951