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1.
A combined (1)H NMR and HPLC-MS-based metabonomic study of urine from obese (fa/fa) Zucker and normal Wistar-derived rats.
J Pharm Biomed Anal
; 38(3): 465-71, 2005 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15925248
2.
Novel application of reversed-phase UPLC-oaTOF-MS for lipid analysis in complex biological mixtures: a new tool for lipidomics.
J Proteome Res
; 6(2): 552-8, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17269712
3.
A metabonomic study of strain- and age-related differences in the Zucker rat.
Rapid Commun Mass Spectrom
; 21(13): 2039-45, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17534859
4.
A gender-specific discriminator in Sprague-Dawley rat urine: the deployment of a metabolic profiling strategy for biomarker discovery and identification.
Anal Biochem
; 362(2): 182-92, 2007 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17266915
5.
Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies.
Anal Chem
; 78(2): 363-71, 2006 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16408915
6.
Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis.
Anal Chem
; 78(13): 4398-408, 2006 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16808447
7.
A rapid screening approach to metabonomics using UPLC and oa-TOF mass spectrometry: application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice.
Analyst
; 130(6): 844-9, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15912231
8.
Use of liquid chromatography/time-of-flight mass spectrometry and multivariate statistical analysis shows promise for the detection of drug metabolites in biological fluids.
Rapid Commun Mass Spectrom
; 17(23): 2632-8, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14648901
9.
Metabonomics: the use of electrospray mass spectrometry coupled to reversed-phase liquid chromatography shows potential for the screening of rat urine in drug development.
Rapid Commun Mass Spectrom
; 16(20): 1991-6, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12362392
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