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1.
Molecules ; 28(3)2023 Jan 19.
Artículo en Inglés | MEDLINE | ID: mdl-36770676

RESUMEN

Dry grape peel powder was extracted by three different techniques, stirred tank reactor, Soxhlet and ultrasound extraction. The composition, physical and chemical structure and inherent stability of the extracts were characterized by various methods. The extracts and reference compounds were added to polyethylene and their stabilization efficiency was determined in multiple extrusion experiments. The composition of the extracts was quite similar. Ten main compounds were identified in the extracts, which contained a considerable number of polyphenols, but only small amounts of quercetin and trans-resveratrol. The extracts proved to be more efficient processing stabilizers than trans-resveratrol and the commercial stabilizer, Irganox 1010, irrespective of the extraction technology used. In spite of their good processing stabilization effect, polymers containing the extracts had poor residual stability. The differences in processing and long-term stabilization must be related to the different structures of the polyphenols contained by the extracts and the reference compounds. The results clearly prove that the IC50 value determined by the DPPH assay is not suitable for the estimation of the efficiency of a compound as a stabilizer for polymers.


Asunto(s)
Vitis , Resveratrol , Vitis/química , Polietileno , Extractos Vegetales/química , Polifenoles/química , Antioxidantes/química
2.
Neurocase ; 26(3): 156-166, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-32420799

RESUMEN

This paper presents the performance of a young amnesic person (CJ) in the DRM task. CJ was found to be sensitive to the DRM manipulation at a level comparable to controls in recognition and at a level higher than controls in free recall. Detailed analyses of recall intrusions lent further support to the finding that CJ is able to extract gist on the basis of semantic associations. Results are discussed with reference to relevant theory as well as the potential role of an impaired and immature cognitive system in adopting a semantic gist strategy in the absence of episodic memory.


Asunto(s)
Amnesia/fisiopatología , Asociación , Neoplasias Encefálicas/complicaciones , Disfunción Cognitiva/fisiopatología , Formación de Concepto/fisiología , Recuerdo Mental/fisiología , Reconocimiento en Psicología/fisiología , Adolescente , Amnesia/etiología , Supervivientes de Cáncer , Disfunción Cognitiva/etiología , Humanos , Masculino
3.
Neurocase ; 23(3-4): 220-229, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28859551

RESUMEN

Recollection has been described as both a recognition memory judgment requiring cognitive control and the ability to retrieve contextual information about a prior occurrence. At the core of this article is the question whether or not these two subcomponents of recollection are dissociable in amnesia. In three experiments, we explored the influence of exclusion task instructions on performance in a single case (CJ), with the view to understand the relative contributions of control and source memory to recognition memory decisions. First, contrasting findings were obtained between tasks requiring strategic control or source reports. Second, even though CJ displayed some residual source memory relative to the ability to strategically control this information, his source memory capacity was time-limited. Our findings resonate with the novel proposal that recollection draws heavily upon working memory resources, and provide an example of how amnesic patients might utilize residual working memory capacity to solve episodic memory tasks.


Asunto(s)
Amnesia Anterógrada/psicología , Función Ejecutiva , Recuerdo Mental , Reconocimiento en Psicología , Adolescente , Humanos , Masculino , Memoria a Corto Plazo , Pruebas Neuropsicológicas
4.
PLoS One ; 18(6): e0286305, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37267278

RESUMEN

Evidence suggesting that episodic specificity induction improves divergent thinking performance in younger and older adults has been taken as indicative of the role of declarative memory processes in creativity. A series of studies were carried out to verify the specificity of such findings by investigating the effects of several novel episodic and semantic memory induction procedures on a widely employed measure of divergent creative thinking (the Alternate Uses Task), in comparison to a control induction and a no-induction baseline in both younger and older adults. There was no clear evidence for a specific role played by the induction of episodic or semantic memory processes in facilitating creative thinking across the three experiments, and the effects of the induction procedures (episodic, semantic and control) on divergent thinking were not comparable across age groups. On the other hand, higher levels of creativity were generally associated with older adults (60-80 years). In Experiments 2 and 3, older adults generated a greater number of responses (fluency), more unique responses (average originality, peak originality, creativity ratings) and more varied responses (flexibility) than younger adults (18-30 years). The findings are discussed in relation to the specificity of declarative memory operations and their impact on creative thinking, especially within the context of healthy ageing.


Asunto(s)
Envejecimiento Saludable , Memoria Episódica , Pensamiento/fisiología , Semántica , Creatividad , Memoria
5.
Child Adolesc Psychiatry Ment Health ; 17(1): 124, 2023 Oct 27.
Artículo en Inglés | MEDLINE | ID: mdl-37891679

RESUMEN

OBJECTIVE: This study aimed to evaluate the association between the location (supratentorial or infratentorial) of brain tumors and the development of depression and anxiety in childhood cancer survivors. Understanding the risk factors for the development of depression and anxiety disordersin these patients is crucial for early diagnosis and successful treatment. METHODS: The meta-analysis included articles that listed patients diagnosed with an intracranial tumor before the age of 18 years, provided the location of the tumor, had exact data on the prevalence of anxiety and depression, or measured these disorders using different assessment tools. The search was conducted in five different databases (MEDLINE, Embase, Web of Science, Scopus, and Cochrane Library). Risk of bias was assessed using QUIPS-2. Outcome measures used were prevalences and standardized means. RESULTS: The analysis included 42 eligible articles with a total number of 1071 patients. Relevant articles were cohort studies, cross-sectional studies, and case series. Based on the available data infratentorial brain tumor survivors had significantly higher scores on various assessment tools measuring anxiety (MRAW (raw mean scores): 36.24 [CI (confidence interval): 28.81-43.67]; versus MRAW: 23.21 (CI 0.91-45.51); p = 0.02, and depression (MRAW: 27.57 (CI 14.35-40.78) versus MRAW: 13.84 (CI 11.43-16.26); p < 0.01. CONCLUSION: Childhood infratentorial cancer survivors have more impairments in terms of depression and anxiety; these children and adults should be monitored more frequently and may require closer follow-up on their mental health. The main limitation of our study originates from the lack of data on follow-up times used by different studies.

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