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Anaesth Intensive Care ; 33(4): 452-6, 2005 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-16119485

RESUMEN

Patient-controlled epidural analgesia (PCEA) is used to maintain epidural analgesia following initial intrathecal analgesia. This trial investigated whether a continuous background infusion with PCEA provides superior analgesia to PCEA alone among patients who received combined spinal-epidural (CSE) analgesia during labour Eighty parturients were randomized to either PCEA alone (PCEA) or PCEA with a background infusion of ropivacaine 0.15% with sufentanil 0.75 microg/ml at 2 ml/h (PCEA + CEI). PCEA settings were a bolus of 4 ml of the same analgesic solution with a lockout interval of 15 minutes. Significantly more patients in the PCEA group required at least one anaesthetist intervention for breakthrough pain (27 [71%] vs 10 [25%] in the PCEA + CEI group, P<0.05). Consumption of local anaesthetic (excluding manually administered boluses) was similar between the groups. If anaesthetist-administered boluses were included, more local anaesthetic was consumed by the PCEA group (47.1 +/- 19.4 mg vs 35.6 +/- 12.0 mg in the PCEA + CEI group, P<0.05). We conclude that PCEA with a background infusion provides effective analgesia with less anaesthetist workload and reduced local anaesthetic consumption as compared with PCEA without a background infusion.


Asunto(s)
Analgesia Epidural/métodos , Analgesia Obstétrica/métodos , Analgesia Controlada por el Paciente/métodos , Anestésicos Combinados/uso terapéutico , Adulto , Amidas/administración & dosificación , Analgesia Epidural/efectos adversos , Analgesia Obstétrica/efectos adversos , Analgesia Controlada por el Paciente/efectos adversos , Analgésicos Opioides/administración & dosificación , Anestésicos Combinados/administración & dosificación , Anestésicos Locales/administración & dosificación , Método Doble Ciego , Femenino , Humanos , Infusiones Intravenosas/métodos , Inyecciones Espinales/métodos , Dolor/prevención & control , Dimensión del Dolor/estadística & datos numéricos , Ropivacaína , Sufentanilo/administración & dosificación , Sufentanilo/efectos adversos , Factores de Tiempo , Resultado del Tratamiento
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