Detalles de la búsqueda
1.
A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes.
J Proteome Res
; 21(3): 702-712, 2022 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34982937
2.
Oxidative-stress and long-term hepatotoxicity: comparative study in Upcyte human hepatocytes and hepaRG cells.
Arch Toxicol
; 96(4): 1021-1037, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35156134
3.
In Vitro Models for Studying Chronic Drug-Induced Liver Injury.
Int J Mol Sci
; 23(19)2022 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36232728
4.
The in vitro assessment of the toxicity of volatile, oxidisable, redox-cycling compounds: phenols as an example.
Arch Toxicol
; 95(6): 2109-2121, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34032869
5.
Comparing in vitro human liver models to in vivo human liver using RNA-Seq.
Arch Toxicol
; 95(2): 573-589, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33106934
6.
Improved in vivo efficacy of clinical-grade cryopreserved human hepatocytes in mice with acute liver failure.
Cytotherapy
; 22(2): 114-121, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31987755
7.
Regenerative cell therapy for the treatment of hyperbilirubinemic Gunn rats with fresh and frozen human induced pluripotent stem cells-derived hepatic stem cells.
Xenotransplantation
; 27(1): e12544, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31342573
8.
Stem-cell derived hepatocyte-like cells for the assessment of drug-induced liver injury.
Differentiation
; 106: 15-22, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30844688
9.
Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes.
Arch Toxicol
; 93(2): 519-532, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30426164
10.
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
Arch Toxicol
; 93(6): 1609-1637, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31250071
11.
Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury.
Arch Toxicol
; 92(1): 383-399, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-28762043
12.
Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis.
Toxicol Appl Pharmacol
; 302: 1-9, 2016 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27089845
13.
Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.
Arch Toxicol
; 90(9): 2049-2061, 2016 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-27325232
14.
Metabolic activation and drug-induced liver injury: in vitro approaches for the safety risk assessment of new drugs.
J Appl Toxicol
; 36(6): 752-68, 2016 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-26691983
15.
Human neonatal hepatocyte transplantation induces long-term rescue of unconjugated hyperbilirubinemia in the Gunn rat.
Liver Transpl
; 21(6): 801-11, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25821167
16.
High-content screening technology for studying drug-induced hepatotoxicity in cell models.
Arch Toxicol
; 89(7): 1007-22, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25787152
17.
High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins.
Arch Toxicol
; 89(10): 1847-60, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25160661
18.
Uncovering the toxicity mechanisms of a series of carboxylic acids in liver cells through computational and experimental approaches.
Toxicology
; 504: 153764, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38428665
19.
Protectiveness of NAM-based hazard assessment - which testing scope is required?
ALTEX
; 41(2): 302-319, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38048429
20.
HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.
Arch Toxicol
; 87(6): 1115-27, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23397584