RESUMEN
Metal-organic frameworks (MOFs) constructed by ligands and metal clusters, have been considered as a promising material for photocatalytic water splitting. In this work, a solvent-assisted ligand exchange (SALE) method has been applied through partial reverse substitution of the ligand in NH2 -MIL-125 (Ti) by 1,4-dicarboxybenzene (BDC). This modification strategy can optimize the charge transfer dynamics together with the preserved light absorption, resulting in a 3.3 times higher hydrogen production rate compared to the pristine material under visible-light irradiation. This work broadens the field of ligand modifications of MOFs to boost the photocatalytic performance.
RESUMEN
Hemiphragma heterophyllum Wall. is commonly used in traditional Yi herbal medicine for treating bellyache and toothache. In the current study, an unreported monoterpene glucoside, (S)-thymoquinol O-(6-O-oleuropeoyl)-ß-d-glucopyranoside (1), together with 11 known glucosides were obtained from the whole herb of H. heterophyllum. Their structures were determined based on a detailed analysis of spectroscopic data and acid hydrolysis and methanolysis reactions. Bioassay results showed that compounds 1 and 10 at 40 mg/kg exhibited significant antinociceptive activity in the acetic acid-induced writhing model, with inhibitions of 59.80% and 64.07%, respectively. Moreover, five of the isolates showed moderate anti-α-glucosidase activities with IC50 values ranging from 5.67 to 46.16 µM.