[A study of the sialogogic effect of cevimeline gargle].

The purpose of this study was to clarify the sialogogic effect iveness of cevimeline gargle. Sequential comparison tests were conducted on healthy adult males and females who received both cevimeline and a placebo. The effect was evaluated by measuring the amount of saliva using the Saxon test and Mucus, and by recording the subjects' own perceptions of oral mucosal moisture reported according to 4 levels. First, ten subjects' measurements were taken before gargling, as well as 5 minutes, 90 minutes and 3 hours after gargling. For the cevimeline treatment, the amount of saliva reached the maximum level within 5 minutes after gargling, and a significant salivary secreting effect(p<0. 05-p<0. 001)was observed up to 90 minutes after gargling. The degree of oral moisture also reached the maximum level within 5 minutes after gargling with cevimeline, and a significant moisture effect(p<0. 05-p<0. 001)persisted up to 3 hours after gargling. After safety profiles were determined to be acceptable, an additional 19 subjects entered the study and the same results were observed. The present data, indicating that cevimeline gargle increases the saliva in healthy individuals for at least 3 hours, will be useful in clinical trials of cevimeline gargle for patients with salivary secretion disorder.

Effect of educational environments on nursing faculty members' perceptions regarding oral care.

AIM: To investigate nursing faculty members' perceptions of oral care and to identify the effects of an educational environment on their perceptions. METHODS: A cross-sectional questionnaire regarding oral care was conducted at eight nursing schools in Japan. A total of 156 (71.6%) faculty members participated in this study. Their perceptions of oral care practice were compared by using a statistical analysis according to the length of work experience, teaching field, school, and facility setting (defined as whether the school had an affiliated hospital with a dental department). RESULTS: Almost all of the faculty members were nurses and most were female. Almost all perceived that oral care was effective in the prevention of aspiration pneumonia and frailty. There were significant differences by teaching field in the nurses' perceptions regarding with whom they should collaborate to conduct oral care and there were significant differences by school in the nurses' perceptions regarding who should provide oral care, where it should be provided, and what kinds of knowledge are important for practice. Perceptions of low involvement in oral care were significantly associated with the schools having an affiliated university hospital with a dental department. CONCLUSION: There were different perceptions regarding oral care among nursing faculty members and their perceptions might have been affected by their educational environment. Therefore, it is suggested that oral care education should be standardized and nursing faculty members should standardize the curriculum regarding oral care for nursing students.