RESUMEN
Copper nanowire-based transparent conductive films have garnered extensive attention owing to their cost-effectiveness and comparable electrical properties. However, the inherent instability of copper nanowires (Cu NWs) has curtailed their extensive utility and applicability. Herein, we present durable Cu@Au NW/PET films exhibiting elevated photoelectric attributes and remarkable flexibility. After preparing Cu NWs, the purification operation allows the purity of the Cu NWs to reach about 98%. Subsequently, Cu@Au NWs/PET flexible transparent conductive films (FTCFs) were prepared through vacuum filtration of Cu NWs and direct treatment with chloroauric acid. The resulting Cu@Au NW-based FTCFs exhibit impressive attributes including a low sheet resistance of 30 ohms per square and a high optical transmittance of 90%, resulting in an exceptional figure of merit (FOM) of 99. Remarkably, the Cu@Au NWs/PET film showed remarkable flexibility, retaining its properties after 10 000 cycles of continuous bending. Stability assessments further affirm the sheet resistance of the Cu@Au NW FTCFs remains nearly unchanged over 75 days at ambient temperature. The strategic integration of a gold nanolayer, serving as a protective coating on the Cu NWs, yields substantial enhancements in both electrical conductivity and overall stability within the Cu NW FTCF architecture. Furthermore, the obtained Cu@Au NW films exhibit rapid heating capabilities, reaching a temperature of 67 °C within 30 seconds at 3.5 V and subsequently returning to room temperature at the same rate. In summary, the introduction of a Au protective layer can effectively enhance the oxidation resistance of Cu NWs, which has great application potential in FTCFs in the field of film heaters.
RESUMEN
Importance: In China and other parts of the world, hospital personnel adherence to evidence-based stroke care is limited. Objective: To determine whether a multifaceted quality improvement intervention can improve hospital personnel adherence to evidence-based performance measures in patients with acute ischemic stroke (AIS) in China. Design, Setting, and Participants: A multicenter, cluster-randomized clinical trial among 40 public hospitals in China that enrolled 4800 patients hospitalized with AIS from August 10, 2014, through June 20, 2015, with 12-month follow-up through July 30, 2016. Interventions: Twenty hospitals received a multifaceted quality improvement intervention (intervention group; 2400 patients), including a clinical pathway, care protocols, quality coordinator oversight, and performance measure monitoring and feedback. Twenty hospitals participated in the stroke registry with usual care (control group; 2400 patients). Main Outcomes and Measures: The primary outcome was hospital personnel adherence to 9 AIS performance measures, with co-primary outcomes of a composite of percentage of performance measures adhered to, and as all-or-none. Secondary outcomes included in-hospital mortality and long-term outcomes (a new vascular event, disability [modified Rankin Scale score, 3-5], and all-cause mortality) at 3, 6, and 12 months. Results: Among 4800 patients with AIS enrolled from 40 hospitals and randomized (mean age, 65 years; women, 1757 [36.6%]), 3980 patients (82.9%) completed the 12-month follow-up of the trial. Patients in intervention group were more likely to receive performance measures than those in the control groups (composite measure, 88.2% vs 84.8%, respectively; absolute difference, 3.54% [95% CI, 0.68% to 6.40%], P = .02). The all-or-none measure did not significantly differ between the intervention and control groups (53.8% vs 47.8%, respectively; absolute difference, 6.69% [95% CI, -0.41% to 13.79%], P = .06). New clinical vascular events were significantly reduced in the intervention group compared with the control group at 3 months (3.9% vs 5.3%, respectively; difference, -2.03% [95% CI, -3.51% to -0.55%]; P = .007), 6 months (6.3% vs 7.8%, respectively; difference, -2.18% [95% CI, -4.0% to -0.35%]; P = .02) and 12 months (9.1% vs 11.8%, respectively; difference, -3.13% [95% CI, -5.28% to -0.97%]; P = .005). Conclusions and Relevance: Among 40 hospitals in China, a multifaceted quality improvement intervention compared with usual care resulted in a statistically significant but small improvement in hospital personnel adherence to evidence-based performance measures in patients with acute ischemic stroke when assessed as a composite measure, but not as an all-or-none measure. Further research is needed to understand the generalizability of these findings. Trial Registration: ClinicalTrials.gov Identifier: NCT02212912.