Asunto(s)
Neoplasias Pulmonares , Melanoma , Neoplasias de la Próstata , Programa de VERF , Neoplasias Cutáneas , Neoplasias de la Tiroides , Neoplasias de la Vejiga Urinaria , Humanos , Masculino , Programa de VERF/estadística & datos numéricos , Neoplasias Cutáneas/epidemiología , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/patología , Incidencia , Melanoma/epidemiología , Melanoma/diagnóstico , Neoplasias Pulmonares/epidemiología , Neoplasias Pulmonares/diagnóstico , Neoplasias de la Vejiga Urinaria/epidemiología , Neoplasias de la Vejiga Urinaria/diagnóstico , Estados Unidos/epidemiología , Femenino , Neoplasias de la Próstata/epidemiología , Neoplasias de la Próstata/diagnóstico , Neoplasias de la Tiroides/epidemiología , Neoplasias de la Tiroides/diagnóstico , Persona de Mediana Edad , Neoplasias Renales/epidemiología , Neoplasias Renales/diagnóstico , Anciano , Linfoma de Células B/epidemiología , Linfoma de Células B/diagnóstico , Adulto , Neoplasias Primarias Secundarias/epidemiología , Neoplasias Primarias Secundarias/diagnósticoRESUMEN
Acute generalised exanthematous pustulosis (AGEP) is a rare cutaneous disorder that presents with numerous non-follicular, pinpoint sterile pustules on a background of oedematous erythema that can coalesce, leading to desquamation. 90% of cases are triggered by medications, most often with antibiotics as the culprit. However, other triggers including viral infection have also been reported. Herpes simplex virus (HSV) as a viral trigger has not been previously explored. Here, we present a case of AGEP caused by bupropion, followed by a second presentation of assumed acute limited exanthematous pustulosis in the setting of disseminated HSV. This case may represent the first report of AGEP and HSV overlap. It also presents the interesting dilemma of differentiating AGEP and disseminated HSV (which can present similarly) as well as determining appropriate treatment and the utility versus risk of systemic steroid administration.