[The correlation between prognostic factors and outcome of second look laparotomy in ovarian cancer]. / Ocena zaleznosci pomiedzy wybranymi czynnikami prognostycznymi a wynikiem operacji sprawdzajacej typu "second look" u chorych na raka jajnika.

OBJECTIVES: The objective of this study was to verify the correlation between prognostic factors, positive or negative second look laparotomy (SLL) and 5-year survival in patients with ovarian cancer. MATERIAL: Between 1984 and 1993, 178 patients after primary surgery and first-line chemotherapy with complete clinical response underwent second look laparotomy. The correlation between clinical stage and grade of cancers, residual disease, age of patients in two group of patients: with positive and negative second look laparotomy were evaluated. RESULTS: 95 patients (53%) had positive SLL. The 5-years survival in this group was only 20%. Adverse prognostic factors were: advanced primary stage (IV-0% of 5-years survival), low grade of differentiation (9.1% of 5-years survival) and residual disease > 2cm (9.4% of 5-years survival). The 5-year survival in group with negative SLL was 78.3%. The analysed prognostic factors in this group were insignificant in predicting 5-year survival. CONCLUSIONS: This study confirms that the SLL can provide an important prognostic evaluation in patients without evidence of disease and allows surgical cytoreduction in group with positive SLL (more than 50% of patients). The analyzed prognostic factors in group with negative SLL were insignificant in predicting 5-year survival. The multicenter research for new prognostic factors in this group are required.

[Co-existence of myoma uteri and pregnancy]. / Ciaza powiklana obecnoscia miesniaków macicy.

OBJECTIVE: Myomas of uterus are the most common mild tumours of uterus. There is often observed the rapid increase of them during the pregnancy and then they could caused complications from 0.3% to 2.6% of pregnancies. DESIGN: The aim of study was the general valuation of the course and delivery means of the pregnancies coexisted with myoma uteri. MATERIALS AND METHODS: We have analysed 11 pregnancies, which we observed during hospitalisation of pregnant women at 2nd Department of Obstetrics and Gynaecology at Medical University of Gdansk. RESULTS: We observed pain in abdomen during pregnancy in 63.6% of analysed group. The 6 (54.5%) pregnant women were pharmacologically treated against symptoms of miscarriages and preterm labors. We investigated in the connection of the complicated pregnancy at women with myomatous uterus. The results confirm the high risk of the pregnancy. Almost 82% of analysed group delivered at time. The frequency of caesarean sections in our study was about 36%, but 2 of them were performed because of myomas. CONCLUSION: We made conclusion that pregnancy complicated by myomas had not significant increase in failure at the end. Myomatous uterus in pregnancy required to be quickly diagnosed and take care to prevent complications.