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1.
J Obstet Gynaecol Can ; 46(4): 102341, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38176678

RESUMEN

Placenta accreta spectrum (PAS) comprising placenta accreta, increta, and percreta, is 1 of the leading causes of peripartum hemorrhage and accounts for up to 50% of all cesarean hysterectomies (CH). We analyzed the data of 216 parturients with PAS who underwent cesarean delivery (CD) and/or CH. Intraoperative surgical complications were noted in 215 (99.5%). The mean estimated blood loss was 2743 (1790) mL, and 105 parturients (48.6%) lost ≥2500 mL. The patients experienced high rates of severe acute maternal morbidity [162 (75%)], hysterectomy [82 (38%)], large volume blood loss, blood transfusion, peripartum anemia, and prolonged hospital stay.


Asunto(s)
Cesárea , Placenta Accreta , Centros de Atención Terciaria , Humanos , Femenino , Embarazo , Placenta Accreta/cirugía , Placenta Accreta/epidemiología , Estudios Retrospectivos , Adulto , Cesárea/estadística & datos numéricos , Omán/epidemiología , Histerectomía/estadística & datos numéricos , Hemorragia Posparto/epidemiología , Pérdida de Sangre Quirúrgica/estadística & datos numéricos , Tiempo de Internación/estadística & datos numéricos , Adulto Joven
2.
J Cardiothorac Vasc Anesth ; 37(12): 2561-2571, 2023 12.
Artículo en Inglés | MEDLINE | ID: mdl-37730455

RESUMEN

OBJECTIVES: The effect of one-lung ventilation (OLV) strategy based on low tidal volume (TV), application of positive end-expiratory pressure (PEEP), and alveolar recruitment maneuvers (ARM) to reduce postoperative acute respiratory distress syndrome (ARDS) and pulmonary complications (PPCs) compared with higher TV without PEEP and ARM strategy in adult patients undergoing lobectomy or pneumonectomy has not been well established. DESIGN: Multicenter, randomized, single-blind, controlled trial. SETTING: Sixteen Italian hospitals. PARTICIPANTS: A total of 880 patients undergoing elective major lung resection. INTERVENTIONS: Patients were randomized to receive lower tidal volume (LTV group: 4 mL/kg predicted body weight, PEEP of 5 cmH2O, and ARMs) or higher tidal volume (HTL group: 6 mL/kg predicted body weight, no PEEP, and no ARMs). After OLV, until extubation, both groups were ventilated using a tidal volume of 8 mL/kg and a PEEP value of 5 cmH2O. The primary outcome was the incidence of in-hospital ARDS. Secondary outcomes were the in-hospital rate of PPCs, major cardiovascular events, unplanned intensive care unit (ICU) admission, in-hospital mortality, ICU length of stay, and in-hospital length of stay. MEASUREMENTS AND MAIN RESULTS: ARDS occurred in 3 of 438 patients (0.7%, 95% CI 0.1-2.0) and in 1 of 442 patients (0.2%, 95% CI 0-1.4) in the LTV and HTV group, respectively (Risk ratio: 3.03 95% CI 0.32-29, p = 0.372). Pulmonary complications occurred in 125 of 438 patients (28.5%, 95% CI 24.5-32.9) and in 136 of 442 patients (30.8%, 95% CI 26.6-35.2) in the LTV and HTV group, respectively (risk ratio: 0.93, 95% CI 0.76-1.14, p = 0.507). The incidence of major complications, in-hospital mortality, and unplanned ICU admission, ICU and in-hospital length of stay were comparable in both groups. CONCLUSIONS: In conclusion, among adult patients undergoing elective lung resection, an OLV with lower tidal volume, PEEP 5 cmH2O, and ARMs and a higher tidal volume strategy resulted in low ARDS incidence and comparable postoperative complications, in-hospital length of stay, and mortality.


Asunto(s)
Ventilación Unipulmonar , Síndrome de Dificultad Respiratoria , Adulto , Humanos , Método Simple Ciego , Pulmón , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/prevención & control , Síndrome de Dificultad Respiratoria/epidemiología , Síndrome de Dificultad Respiratoria/etiología , Volumen de Ventilación Pulmonar , Peso Corporal
3.
J Pak Med Assoc ; 72(10): 1954-1962, 2022 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-36660981

RESUMEN

Objective: To find out the most common reasons for refusing orthognathic surgery and to compare the responses along gender lines and in terms of open-ended and closed-ended approaches. METHODS: The cross-sectional retrospective study was conducted from August to December 2020 at the Orthodontics Department of Bahria University Medical and Dental College, Karachi, Pakistan, and comprised of patients who were planned for but refused orthognathic surgical treatment between January 2018 and July 2020. Data was collected through telephone-based interviews to record reasons of avoiding orthognathic surgery. The data-collection tool had both open-ended and closed-ended questions. Data was analysed using SPSS 23. RESULTS: Of the 60 patients, 42(70%) were females and 18(30%) were males with a mean age range of 23.25±2.19years. Overall, 19(31.7%) patients avoided surgery due to additional expense, while post-operative pain was cited as a reason by 35(58.3%) patients. Males were 9 times more concerned about their dental alignment compared to females (p=0.005). Fear of tooth injury (p<0.0001) and intra-operation and post-operation bleeding (p<0.0001) were found twice in males than females. Conclusion: The most common reasons for refusal to have orthognathic surgery were increased cost and post-operative pain. Males were more concerned about dental alignment and had higher fear of post-surgical tooth injury and intra- and post-operative bleeding compared to the females.


Asunto(s)
Cirugía Ortognática , Procedimientos Quirúrgicos Ortognáticos , Masculino , Femenino , Humanos , Adulto Joven , Adulto , Estudios Retrospectivos , Estudios Transversales , Dolor Postoperatorio
4.
Br J Anaesth ; 122(1): 120-130, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-30579390

RESUMEN

BACKGROUND: Perioperative studies of patients following hip fracture have large heterogeneity within their reported outcomes. This study aimed to develop a core outcome set for use in perioperative studies comparing the types of anaesthesia for hip fracture surgery. METHODS: The consensus process consisted of a systematic review of the literature, three rounds of a Delphi survey, two consensus webinars, and face-to-face patient meetings. RESULTS: The Delphi participants represented nine stakeholder groups. The numbers of participants completing Rounds 1-3 were 242, 186, and 169, respectively. Seventeen outcomes that met the predefined consensus criteria were considered at two consensus meetings. A final set of 10 core outcomes was agreed: mortality, time from injury to surgery, acute coronary syndrome, hypotension, acute kidney injury, delirium, pneumonia, orthogeriatric input, being out of bed at day 1, and pain. CONCLUSIONS: We generated a consensus-based set of core outcomes recommended for use in all perioperative trials evaluating the effects of anaesthesia for hip fracture surgery. An important next step is developing consensus-based consistency on how they should be measured. CLINICAL TRIAL REGISTRATION: http://www.comet-initiative.org/studies/details/757.


Asunto(s)
Anestesia/métodos , Fijación de Fractura/métodos , Fracturas de Cadera/cirugía , Anestesia/efectos adversos , Técnica Delphi , Determinación de Punto Final , Fijación de Fractura/mortalidad , Fracturas de Cadera/mortalidad , Humanos , Morbilidad , Evaluación de Resultado en la Atención de Salud , Complicaciones Posoperatorias/etiología
5.
Br J Anaesth ; 122(1): 60-68, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-30579407

RESUMEN

BACKGROUND: Delirium is frequently unrecognised. EEG shows slower frequencies (i.e. below 4 Hz) during delirium, which might be useful in improving delirium recognition. We studied the discriminative performance of a brief single-channel EEG recording for delirium detection in an independent cohort of patients. METHODS: In this prospective, multicentre study, postoperative patients aged ≥60 yr were included (n=159). Before operation and during the first 3 postoperative days, patients underwent a 5-min EEG recording, followed by a video-recorded standardised cognitive assessment. Two or, in case of disagreement, three delirium experts classified each postoperative day based on the video and chart review. Relative delta power (1-4 Hz) was based on 1-min artifact-free EEG. The diagnostic value of the relative delta power was evaluated by the area under the receiver operating characteristic curve (AUROC), using the expert classification as the gold standard. RESULTS: Experts classified 84 (23.3%) postoperative days as either delirium or possible delirium, and 276 (76.7%) non-delirium days. The AUROC of the relative EEG delta power was 0.75 [95% confidence interval (CI) 0.69-0.82]. Exploratory analysis showed that relative power from 1 to 6 Hz had significantly higher AUROC (0.78, 95% CI 0.72-0.84, P=0.014). CONCLUSIONS: Delirium/possible delirium can be detected in older postoperative patients based on a single-channel EEG recording that can be automatically analysed. This objective detection method with a continuous scale instead of a dichotomised outcome is a promising approach for routine detection of delirium. CLINICAL TRIAL REGISTRATION: NCT02404181.


Asunto(s)
Delirio/diagnóstico , Complicaciones Posoperatorias/diagnóstico , Anciano , Anciano de 80 o más Años , Algoritmos , Electroencefalografía/métodos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Monitoreo Fisiológico/métodos , Cuidados Posoperatorios/métodos , Curva ROC , Reproducibilidad de los Resultados , Procesamiento de Señales Asistido por Computador
6.
Orthopade ; 48(9): 744-751, 2019 Sep.
Artículo en Alemán | MEDLINE | ID: mdl-31392387

RESUMEN

BACKGROUND: The majority of osteoarticular defects after tumor resection in adolescent and adult patients are reconstructed using megaendoprosthetic implants. However, even infant and pre-teen children undergo reconstruction of defects using so-called growing prostheses with an increasing frequency. OBJECTIVES: Presentation of current techniques, outcomes and the most common complications of megaendoprosthetic reconstruction following tumour resection. METHODS: Selective literature review and discussion of current concepts and knowledge in megaendoprosthetic reconstruction against personal experience and treatment strategies. RESULTS: Megaendoprosthetic reconstructions achieve good functional results and long-term limb salvage (ca. 90% of cases) in adolescent and adult patients. Still, periprosthetic infection and mechanical failure of joint components are among the most common complications observed. In infant and pre-teen children treated by reconstruction using a growing prosthesis, mandatory maintenance operations-in the process of elongating the implant-must also be considered when assessing complication risks. CONCLUSIONS: Megaendoprosthetic reconstructions of osteoarticular defects are a standard procedure in adolescent and adult patients. Despite a substantial complication rate, limb salvage is achieved in a majority of patients. When using growing prostheses in younger children, one needs to be aware of additional servicing procedures that occur independently of those arising from complications.


Asunto(s)
Neoplasias Óseas , Recuperación del Miembro , Prótesis e Implantes , Adolescente , Adulto , Niño , Humanos , Estudios Retrospectivos , Factores de Riesgo , Resultado del Tratamiento
7.
Radiologe ; 57(11): 891-906, 2017 Nov.
Artículo en Alemán | MEDLINE | ID: mdl-29046932

RESUMEN

CLINICAL/METHODICAL ISSUE: Postoperative imaging of the ankle can be challenging, even for the experienced radiologist. Pathological and postoperative changes to the primarily complex anatomy of the ankle with its great variety of bone structures, tendons, ligaments, and soft tissue in a very limited space may cause great difficulty in differentiating underlying pathology from expected postoperative changes and artifacts, especially in magnetic resonance imaging (MRI). STANDARD RADIOLOGICAL METHODS: Selecting the appropriate radiological modality is key to making the correct diagnosis. Therefore, knowledge of the initial and current symptoms is just as important as familiarity with the most frequently performed operations in the ankle. PRACTICAL RECOMMENDATIONS: This article aims to give its reader a summary of the most important and frequently performed operation techniques of the ankle and discusses the expected appearance and possible complications in postoperative imaging.


Asunto(s)
Articulación del Tobillo/diagnóstico por imagen , Articulación del Tobillo/cirugía , Imagen por Resonancia Magnética , Complicaciones Posoperatorias/diagnóstico por imagen , Traumatismos del Tobillo/diagnóstico por imagen , Traumatismos del Tobillo/cirugía , Fijación Interna de Fracturas/instrumentación , Fracturas no Consolidadas/diagnóstico por imagen , Humanos
8.
J Metab Bariatr Surg ; 13(1): 27-33, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38974894

RESUMEN

Purpose: Laparoscopic sleeve gastrectomy (LSG) is one of the most common surgical procedures worldwide for the treatment of morbid obesity. Blake-type drains are widely used in this procedure despite the lack of clear evidence regarding their benefits in the diagnosis and treatment of common postoperative complications such as gastric suture line leak (GSLL) and postoperative bleeding (PB). Materials and Methods: A retrospective descriptive study with prospective case registry was conducted, analyzing all patients who underwent LSG between January 2012 and December 2022 at a high-volume center. Our primary outcome was to evaluate the role of drains for diagnosis and treatment of GSLL and PB in LSG. Our secondary outcome was to determine drain related surgical site infection (DRSSI) rate. Results: A total of 335 LSG were performed in the studied period. In all patients one abdominal drain was placed during surgery. Six GSLL (1.79%) and 5 PB (1.49%) were recorded. Drain placement did not prove to ensure early diagnosis or conservative management of GSLL or PB after LSG. Furthermore, an incidence of DRSSI of 4.1% (14 patients) was found. Conclusion: In our study, no clear diagnostic or therapeutic benefits of the systematic use of drains for GSLL or PB in LSG was found; but drain use did show a considerable rate of DRSSI, which must be taken into consideration prior to considering drain systematic use. While no randomized prospective trials have been performed, the retrospective data does not support drain systematic use.

9.
Front Oncol ; 12: 1011849, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36237329

RESUMEN

Background: Both double-lumen tube (DLT) and bronchial blocker (BB) are used for lung isolation in patients undergoing lung cancer surgery. However, the effects of different devices for lung isolation remain inconclusive. Present study was designed to investigate the association between the choice of the two devices and postoperative pulmonary complications (PPCs) in patients with lung cancer. Methods: In this retrospective cohort study, patients who underwent lung cancer surgery between January 1, 2020 and October 31, 2020 were screened. Patients were divided into two groups according to different devices for lung isolation: DLT group and BB group. Primary outcome was the incidence of a composite of PPCs during postoperative in-hospital stay. Results: A total of 1721 were enrolled for analysis, of them, 868 received DLT and 853 BB. A composite of PPCs was less common in patients with BB (25.1%, [214/853]) than those received DLT (37.9% [329/868] OR 0.582 95% CI 0.461-0.735 P < 0.001). Respiratory infection was less common in BB group (14.4%, [123/853]) than DLT group (30.3%, [263/868], P<0.001). The incidence of non-PPCs complications was not statistically significant between the 2 groups. Conclusions: For patients undergoing surgery for lung cancer, the use of BB for lung isolation was associated with a reduced risk of PPCs when compared with DLT.

10.
Perioper Med (Lond) ; 9: 20, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32626573

RESUMEN

BACKGROUND: Multiple tools exist estimating perioperative risk. With an ageing surgical demographic, frailty is becoming an increasingly important concept in perioperative medicine due to its association with adverse post-operative outcomes. Reduced physical activity is a hallmark of frailty, and we postulate that a low pre-operative step count may be an objective measure of frailty. This study aimed to determine the association between low pre-operative step count and post-operative outcomes in patients undergoing elective colorectal cancer surgery. METHODS: A prospective analysis of 85 older patients undergoing major elective colorectal surgery was performed at a tertiary centre between October 2017 and October 2018. Patients aged 65 years and over who met inclusion criteria were provided with an activity tracker to wear for 14 days prior to planned surgery. Their median daily step count was measured and a cut-off of < 2500 steps/day was used to define a reduced step count. Primary outcomes included length of stay and 30-day post-operative complication rate. Multivariable logistic regression analyses were used to analyze the influence of low pre-operative step count and other preoperative variables, on post-operative outcomes including mortality, prolonged hospital admission, and complication rates. RESULTS: Of 85 patients, 17 (20%) were identified as having a low pre-operative step count. A low pre-operative step count was associated with a significantly increased length of stay (14 vs. 6 days, IRR 2.09, 95% CI 1.55-2.83, p ≤ 0.01) and rate of major post-operative complications (29.4% vs. 8.8%, OR 3.34, 95% CI 1.03-14.3, p = 0.04). It was also associated with significantly increased rates of discharge to care facilities (p < 0.01) and requiring support on discharge (p = 0.03). CONCLUSION: Low pre-operative step count (< 2500 steps/day) is predictive of an increased risk of post-operative morbidity in patients undergoing elective colorectal surgery. Accurate preoperative identification may allow for treatment modification and tailored perioperative care. The possibility of using a wearable activity tracker as a simple but powerful pre-habilitation tool is raised as an important avenue for future study. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry (ACTRN12618000045213).

11.
rev.cuid. (Bucaramanga. 2010) ; 13(3): 1-16, 20220831.
Artículo en Español | LILACS, BDENF, COLNAL | ID: biblio-1402553

RESUMEN

Introducción: Los procedimientos de traqueostomía van en aumento en las unidades de cuidados intensivos en el adulto, por lo que las complicaciones asociadas a este procedimiento también incrementan. Se ha identificado que la traqueostomía puede conllevar a complicaciones tanto preoperatorias como postoperatorias, que varían ampliamente entre un 5-40%, entre las más frecuentes están, estenosis traqueal, fístula traqueoesofágica, hemorragia, lesión peristomal, decanulación, infecciones, entre otras, que podrían causar la muerte hasta en 1,4% de las personas. Sin embargo, a nivel mundial muy pocos estudios abordan los conceptos causales o factores de riesgo mecánicos y no mecánicos de este importante tema. Objetivo: Revisar el alcance de la literatura científica disponible sobre las complicaciones de origen mecánico y no mecánico asociadas a la traqueostomía en pacientes adultos en las unidades de cuidados intensivos entre el periodo 2015-2020. Materiales y métodos: se establecieron la pregunta de investigación con metodología "Patient, Intervention, Comparation, Outcome, Time (PICOT)" y los criterios de inclusión para la búsqueda de los referentes bibliográficos de estudios observacionales y experimentales. La información fue consultada en las bases de datos PubMed y EBSCO y los artículos científicos seleccionados fueron los publicados entre los años 2015-2020. Como guía metodológica y de calidad para el presente estudio se utilizó la lista de chequeo PRISMA-ScR. Resultados: las complicaciones con mayor frecuencia son: sangrado 61% presentada (13/21 artículos), estenosis traqueal 28,5% (5/21 artículos), decanulación 23,6% (5/21 artículos), infección de la estoma 19% (4/21 artículos) muerte 19% (4/21) y la dificultad en la inserción de la cánula 19% (4/21 artículos), en cuanto a factores de riesgo mecánicos para éstas sólo se identifica el uso de la técnica Bjork flap (OR=0,4). Entre los no mecánicos se encontraron, obesidad (OR=5,15), diámetro de cánula >6 (OR= 2,6) y ventilación mecánica preoperatoria (OR=3,14). Conclusión:Se logró identificar que las complicaciones relacionadas con la traqueostomía con mayor incidencia son sangrado, estenosis traqueal, decanulación accidental y la muerte. Sin embargo, aún se desconoce si se originan por una causa mecánica o no mecánica durante su manejo en UCI.


Introduction:Tracheostomy procedures in intensive care units are on the rise; however, they can lead to both perioperative and postoperative complications, with a variable incidence from 5 to 40% and even death in up to 1.4% of individuals. Despite this, few studies address causal concepts or mechanical and nonmechanical risk factors about this important topic. Objetive: To review the scope of the available scientific literature on complications of mechanical and non-mechanical origin associated with a tracheostomy. Materials and Methods:The research question and inclusion criteria were established to conduct the search in PubMed and EBSCO databases between 2015 and 2020. The PRISMA-ScR checklist was used in the present study as a methodological and quality guideline. Results:The most frequent complications were bleeding 61%, tracheal stenosis 28.5%, decannulation 23.6% (5/21) , stoma infection 19%, death 19%, and difficult tracheostomy tube insertion 19%. Regarding mechanical risk factors, only the use of the Bjork flap (OR=0.4) was identified as a protective factor. Among the non-mechanical factors, obesity (OR=5.15), tube diameter >6 (OR=2.6), and preoperative mechanical ventilation (OR=3.14) were found. Conclusions: It was possible to identify that the highest incidence of tracheostomy-related complications were bleeding, tracheal stenosis, accidental decannulation, and death; however, it is still unknown whether they originate from a mechanical or non-mechanical cause during intensive care management.


Introdução: Os procedimentos de traqueostomia estão aumentando nas unidades de terapia intensiva, entretanto, podem levar a complicações perioperatórias e pós-operatórias com uma incidência variável entre 5-40% e até a morte em até 1,4% dos indivíduos, apesar disso, poucos estudos abordam os conceitos causais ou fatores de risco mecânicos e não-mecânicos sobre este importante tópico. Objetivo: Rever o escopo da literatura científica disponível sobre complicações mecânicas e não mecânicas associadas à traqueostomia. Materiais e Métodos: a questão da pesquisa e critérios de inclusão foram estabelecidos para a pesquisa nas bases de dados PubMed e EBSCO entre os anos 2015-2020, como guia metodológico e de qualidade para o presente estudo foi utilizada a lista de verificação PRISMAScR. Resultados: As complicações com maior freqüência foram, sangramento 61%, estenose traqueal 28,5%, decanulação 23,6% (5/21, infecção por estoma 19%, morte 19% e dificuldade na inserção da cânula 19%, em relação aos fatores de risco mecânico, apenas o uso da técnica de Bjork Flap (OR=0,4) foi identificado como fator de proteção, entre os fatores não mecânicos foram encontrados: obesidade (OR=5,15), diâmetro da cânula >6 (OR= 2,6) e ventilação mecânica pré-operatória (OR=3,14). Conclusões: Conseguimos identificar que as complicações relacionadas à traqueostomia com maior incidência foram sangramento, estenose traqueal, decanulação acidental e morte, no entanto, ainda não se sabe se elas se originam de uma causa mecânica ou não mecânica durante a gestão dos cuidados intensivos.


Asunto(s)
Complicaciones Posoperatorias , Traqueostomía , Cuidados Críticos , Complicaciones Intraoperatorias
12.
J Laryngol Otol ; 130 Suppl 1: S20-5, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26687739

RESUMEN

BACKGROUND: There has been increasing emphasis on performing 'same-day' or 'out-patient' thyroidectomy to reduce associated costs. However, acceptance has been limited by the risk of potentially life-threatening post-operative bleeding. This study aimed to review current rates of post-operative bleeding in a metropolitan teaching hospital and identify risk factors. METHOD: Medical records of patients undergoing thyroidectomy between January 2007 and March 2012 were reviewed retrospectively. Pre-operative, operative and pathological data, and post-operative complication data, were examined. RESULTS: The study comprised 205 thyroidectomy cases. Mean age was 51.6 years (standard deviation = 14.74), with 80 per cent females. Unilateral thyroidectomy was performed in 81 cases (39.5 per cent) and total thyroidectomy was performed in 74 cases (36.1 per cent; 5.3 per cent with concomitant lymph node dissection). Nine patients (4.4 per cent) suffered post-operative bleeding, of which six required re-operation. Analysis showed that post-operative systolic blood pressure of 180 mmHg or greater was associated with post-operative bleeding (p = 0.003, chi-square test). CONCLUSION: Rates of significant post-operative bleeding are consistent with recent literature. Post-operative hypertension, diabetes and high post-operative drain output were identified as independent risk factors on multivariate analysis; when identified, these may be caveats to same-day discharge of thyroidectomy patients.


Asunto(s)
Procedimientos Quirúrgicos Ambulatorios/efectos adversos , Hematoma/etiología , Hemorragia Posoperatoria/etiología , Tiroidectomía/efectos adversos , Adulto , Anciano , Procedimientos Quirúrgicos Ambulatorios/estadística & datos numéricos , Presión Sanguínea , Femenino , Humanos , Masculino , Persona de Mediana Edad , Periodo Posoperatorio , Reoperación/estadística & datos numéricos , Estudios Retrospectivos , Factores de Riesgo , Tiroidectomía/estadística & datos numéricos
13.
Case Rep Ophthalmol ; 5(2): 262-6, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-25232340

RESUMEN

A 46-year-old Caucasian female underwent pars plana vitrectomy (ppv) for retinal detachment. After the procedure, the patient could only distinguish hand movements; the condition was tentatively diagnosed as nonarteritic anterior ischemic optic neuropathy. Conventional treatment with systemic corticosteroids and acetylsalicylic acid was ineffective and yielded substantial steroid-related side effects. Additional administration of 2 × 110 mg dabigatran etexilate (Pradaxa(®)), a novel direct thrombin inhibitor, resulted in a prompt and marked improvement of visual acuity, which indicated improved blood flow in the central vessels of the optic nerve. Dabigatran etexilate may provide a promising alternative for the treatment of postprocedural vision loss after ppv.

14.
Belo Horizonte; s.n; 2018. 121 p. tab, graf.
Tesis en Portugués | LILACS, BDENF | ID: biblio-916636

RESUMEN

Introdução: O crescimento pela demanda por serviços de saúde dentre a população idosa está diretamente relacionado ao aumento da expectativa de vida, não somente para a população brasileira, mas mundialmente. Observa-se a expansão no número de procedimentos cirúrgicos realizados em indivíduos com idade ≥ 60 anos e as complicações manifestadas por estes posteriormente a uma intervenção anestésica cirúrgica. Objetivo: Analisar as complicações apresentadas pelos pacientes idosos no período pós-operatório até a alta hospitalar. Método: Trata-se de estudo longitudinal retrospectivo com abordagem quantitativa. A amostra compõe-se de 49 prontuários referente à pacientes idosos que foram acompanhados na Sala de Recuperação Pós Anestésica no período de Junho a Setembro de 2013 em um estudo primário. A coleta dos dados desses pacientes no período em Pós- operatório - dividido em pós-operatório imediato e pós-operatório tardio até a alta hospitalar - foi realizada em prontuários de junho a agosto de 2016. Os testes Exato de Fisher, Mann-Whitney e McNemar foram utilizados para a análise estatística. Resultados: Dos 49 prontuários analisados, mais da metade (53,1%) eram do sexo feminino. A mediana da idade correspondeu a 70 anos. 67,3% foram submetidos à cirurgia na região do abdómen e pelve. O tipo de anestesia de maior percentual foi geral, com 36,7%. A classificação de risco teve 89,8% dos idosos com ASA II. A complicação secreção na Ferida Operatória demostrou correlação significativa com o tipo de anestesia e os tempos de anestesia e cirurgia. A alteração da Frequência Cardíaca também apresentou correlação significativa com o tempo de cirurgia. Marginalmente significativa às complicações hipotermia, dor e motilidade intestinal disfuncional demostraram correlação com o local da cirurgia. Ao comparar as complicações descritas no período de permanência na Sala de Recuperação Pós Anestésica nos tempos zero e 60 minutos com as do período de Pós-operatório até a alta hospitalar, apresentaram correlação significativa quanto à complicação hipertensão; hipotensão; bradipneia e hipotermia. Conclusão: Com base nos resultados expostos, é permissível constatar que as complicações presentes nos idosos no período de permanência em Sala de Recuperação Pós-Anestésica permanecem ao longo do período de Pós-operatório, em especial nas primeiras 48 horas em que o idoso se encontra na unidade de internação cirúrgica.(AU)


Introduction: The growth of the demand for health services among the elderly population is directly related to the increase in life expectancy, not only for the Brazilian population, but worldwide. One can highlight the expansion in the number of surgical procedures performed on individuals aged ≥ 60 years and the complications expressed by these to an anesthetic surgical intervention. Objective: to Analyze the complications presented by the elderly patients in the postoperative period until hospital discharge. Method: retrospective, longitudinal study, with a quantitative approach. The sample consists of 49 records pertaining to the elderly patients who were accompanied in the Post-Anesthesia Recovery Room in the period from June to September 2013 in a primary study. The data collection of these patients in the period of postoperative - divided into immediate postoperative and late post-operative period until hospital discharge - was performed on medical records from June to August of 2016. The tests Fisher's Exact, Mann-Whitney and McNemar were used for the statistical analysis. Results: Of the 49 records reviewed, more than half (53,1%) were female. The average age was 70 years. 67,3% were submitted to surgery in the region of the abdomen and pelvis. The the highest percentage type of anesthesia was general, with 36,7%. The risk rate was 89,8% of the elderly with ASA II. The complication secretion in the Surgical Wound showed a significant correlation with the type of anesthesia and the duration of anesthesia and surgery. The change of the Heart rate also showed significant correlation with the duration of the surgery. Marginally significant to the complications of hypothermia, pain and intestinal motility dysfunctional demonstrated correlation with the location of the surgery. To compare the complications described in the period of rest in the Post-Anesthesia Recovery Room in from zero to 60 minutes to the Post-operative period until hospital discharge, presented a significant correlation as to the complication of hypertension; hypotension; bradipneia and hypothermia. Conclusion: based on the results exposed, it is permissible to find that the complications present in the elderly in the period of rest in the Post-Anesthetic Recovery Room remain throughout the Postoperative period, especially in the first 48 hours in which the elderly person is in the surgical unit.(AU)


Asunto(s)
Humanos , Masculino , Femenino , Anciano , Anciano de 80 o más Años , Alta del Paciente , Complicaciones Posoperatorias/enfermería , Periodo Posoperatorio , Enfermería Perioperatoria , Anciano , Tesis Académica
15.
Rev. bras. anestesiol ; 60(2): 181-191, mar.-abr. 2010. ilus
Artículo en Inglés, Español, Portugués | LILACS | ID: lil-552047

RESUMEN

JUSTIFICATIVA E OBJETIVOS: As distrofias miotônicas são doenças neuromusculares de transmissão autossômica dominante. Dentre elas, a distrofia miotônica tipo 1 (DM1), ou doença de Steinert, é a mais comum no adulto e, além do envolvimento muscular, apresenta manifestações sistêmicas importantes. A DM1 representa um desafio para o anestesiologista. Os pacientes apresentam maior sensibilidade às drogas anestésicas e complicações, principalmente cardíacas e pulmonares. Além disso, há a possibilidade de apresentarem hipertermia maligna e crise miotônica. Descreveu-se o caso de um paciente que teve complicação pulmonar importante após ser submetido à anestesia geral. RELATO DO CASO: Paciente de 39 anos, portador de DM1, foi submetido à anestesia geral para colecistectomia videolaparoscópica. A anestesia foi venosa total com propofol e remifentanil e rocurônio. O procedimento cirúrgico de 90 minutos não apresentou intercorrências, mas após a extubação o paciente apresentou insuficiência respiratória e crise miotônica, que tornou a intubação traqueal impossível. Utilizou-se a máscara laríngea, que possibilitou a oxigenação adequada, e a ventilação mecânica foi mantida até a recuperação total da atividade respiratória. Evolução ocorreu sem outras complicações. CONCLUSÕES: A DM1 é uma doença que apresenta várias peculiaridades para o anestesiologista. O conhecimento minucioso do seu envolvimento sistêmico, associado à ação diferenciada das drogas anestésicas nesses pacientes, proporcionará um ato anestésicocirúrgico mais seguro.


BACKGROUND AND OBJECTIVES: Myotonic dystrophies are autosomal dominant neuromuscular diseases. Among them, myotonic dystrophy type 1 (MD1), or Steinert disease, is the most common in adults, and besides muscular involvement it also has important systemic manifestations. Myotonic dystrophy type 1 poses a challenge to the anesthesiologist. Those patients are more sensitive to anesthetics and prone to cardiac and pulmonary complications. Besides, the possibility of developing malignant hyperthermia and myotonic episodes is also present. CASE REPORT: This is a 39-year old patient with DM1 who underwent general anesthesia for videolaparoscopic cholecystectomy. Total intravenous anesthesia with propofol, remifentanil, and rocuronium was the technique chosen. Intercurrences were not observed in the 90-minute surgical procedure, but after extubation, the patient developed respiratory failure and myotonia, which made tracheal intubation impossible. A laryngeal mask was used, allowing adequate oxygenation, and mechanical ventilation was maintained until full recovery of the respiratory function. The patient did not develop further complications. CONCLUSIONS: Myotonic dystrophy type 1 presents several particularities to the anesthesiologist. Detailed knowledge of its systemic involvement along with the differentiated action of anesthetic drugs in those patients will provide safer anesthetic-surgical procedure.


JUSTIFICATIVA Y OBJETIVOS: Las distrofias miotónicas son enfermedades neuromusculares de transmisión autosómica dominante. Entre ellas está la distrofia miotónica tipo 1 (DM1), o enfermedad de Steinert, que es la más común en el adulto y además de la involucración muscular, presenta manifestaciones sistémicas importantes. La DM1 representa un reto para el anestesiólogo. Los pacientes presentan una mayor sensibilidad a los fármacos anestésicos y complicaciones, principalmente cardíacas y pulmonares. Además de eso, existe la posibilidad de presentar hipertermia maligna y crisis miotónica. Se ha descrito el caso de un paciente que tuvo una complicación pulmonar importante después de haber sido sometido a la anestesia general. RELATO DEL CASO: Paciente de 39 años, portador de DM1, sometido a la anestesia general para colecistectomía videolaparoscópica. La anestesia fue venosa total con propofol y remifentanil y rocuronio. El procedimiento quirúrgico de 90 minutos no presentó intercurrencias, pero después de la extubación, el paciente presentó insuficiencia respiratoria y crisis miotónica, que hizo la intubación traqueal imposible. Se utilizó la máscara laríngea, que posibilitó la oxigenación adecuada, y la ventilación mecánica se mantuvo hasta la recuperación total de la actividad respiratoria. Evolucionó sin otras complicaciones. CONCLUSIONES: La DM1 es una enfermedad que presenta varias peculiaridades para el anestesiólogo. El conocimiento minucioso de su involucración sistémica, asociado a la acción diferenciada de los fármacos anestésicos en esos pacientes, proporcionará un acto anestésico-quirúrgico más seguro.


Asunto(s)
Adulto , Humanos , Masculino , Anestesia/métodos , Colecistectomía Laparoscópica , Distrofia Miotónica , Cirugía Asistida por Video , Colecistectomía Laparoscópica/métodos
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