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1.
J Emerg Med ; 43(4): 663-6, 2012 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-20800412

RESUMEN

BACKGROUND: Bilateral mastoiditis in adults has previously been reported only in association with diabetes mellitus or immunocompromised patients. OBJECTIVES: To describe a case of bilateral mastoiditis in a healthy adult and to investigate the etiology. CASE REPORT: A 53-year-old woman presented to the Emergency Department with bilateral otitis externa and mastoiditis after scuba diving during a harmful algal bloom, commonly known as a "red tide." The levels of coliform bacteria recorded at the time and location of her dive exceeded health regulatory limits and correlate with her atypical culture results. CONCLUSION: Elevated bacterial counts that result from harmful algal blooms may account for this rare infection.


Asunto(s)
Buceo/efectos adversos , Infecciones por Bacterias Grampositivas/complicaciones , Mastoiditis/microbiología , Otitis Externa/microbiología , Infecciones por Pseudomonas/complicaciones , Analgésicos/uso terapéutico , Antibacterianos/uso terapéutico , Dolor de Oído/tratamiento farmacológico , Dolor de Oído/microbiología , Enterococcus , Femenino , Infecciones por Bacterias Grampositivas/tratamiento farmacológico , Floraciones de Algas Nocivas , Humanos , Mastoiditis/etiología , Persona de Mediana Edad , Otitis Externa/etiología , Infecciones por Pseudomonas/tratamiento farmacológico , Pseudomonas aeruginosa
5.
Int J Pediatr Otorhinolaryngol ; 78(12): 2072-8, 2014 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-25281339

RESUMEN

OBJECTIVE: We assessed clinical, radiological, laboratory and microbiological findings in children with acute mastoiditis in order to improve the diagnostics and treatment of these patients. We also investigated whether different pathogens cause different clinical findings of mastoiditis. METHODS: A retrospective review of the medical records of all children aged 0-16 years treated as in-ward patients for acute mastoiditis at Helsinki University Central Hospital, Department of Otorhinolaryngology, between 2003 and 2012. RESULTS: Fifty-six patients met the inclusion criteria. The incidence of mastoiditis was 1.88/100000/year. The most common pathogens were Streptococcus pneumoniae (38%), Streptococcus pyogenes (11%) and Pseudomonas aeruginosa (11%). Of S. pneumoniae, 48% had reduced susceptibility (intermediate or resistant) for the common antimicrobials; this was clearly overrepresented relative to the background population (p<0.001). Otalgia and retroauricular symptoms were common in the patients with S. pneumoniae. Otorrhoea was less common (p=0.03) in these patients relative to the other pathogens. Patients with S. pneumoniae had more destruction of the mastoid septa (p=0.05) than patients with any of the other pathogens. Mastoidectomy was performed in 34% of all cases, it was most common (60%) in the patients with S. pneumoniae with reduced susceptibility. The patients with S. pyogenes had less otalgia and seemed to have less retroauricular symptoms relative to other pathogens. P. aeruginosa especially affected children with tympanostomy tubes, caused otorrhoea in all patients and caused a milder form of disease with less retroauricular swelling (p=0.04) than the other pathogens, and there was no need for mastoidectomies. The younger children (<2 years) had less otorrhoea and more retroauricular symptoms of infection than the older patients. No significant differences emerged in outcome of the patient groups. CONCLUSIONS: The clinical findings of acute mastoiditis differ according to the causative pathogen. S. pneumoniae, especially strains with reduced susceptibility, causes severe symptoms and leads to mastoidectomy more often than the other pathogens. S. pyogenes causes less otalgia than the other pathogens. P. aeruginosa particularly affects children with tympanostomy tubes and causes a less aggressive form of disease.


Asunto(s)
Mastoiditis/tratamiento farmacológico , Mastoiditis/microbiología , Infecciones por Pseudomonas/tratamiento farmacológico , Pseudomonas aeruginosa , Infecciones Estreptocócicas/tratamiento farmacológico , Streptococcus pneumoniae , Streptococcus pyogenes , Enfermedad Aguda , Adolescente , Antibacterianos/uso terapéutico , Niño , Preescolar , Farmacorresistencia Bacteriana , Dolor de Oído/microbiología , Edema/microbiología , Femenino , Humanos , Lactante , Masculino , Apófisis Mastoides/cirugía , Mastoiditis/diagnóstico , Ventilación del Oído Medio , Infecciones por Pseudomonas/diagnóstico , Estudios Retrospectivos , Infecciones Estreptocócicas/diagnóstico
6.
BMJ ; 347: f6867, 2013 Nov 25.
Artículo en Inglés | MEDLINE | ID: mdl-24277339

RESUMEN

OBJECTIVE: To document whether elements of a structured history and examination predict adverse outcome of acute sore throat. DESIGN: Prospective clinical cohort. SETTING: Primary care. PARTICIPANTS: 14,610 adults with acute sore throat (≤ 2 weeks' duration). MAIN OUTCOME MEASURES: Common suppurative complications (quinsy or peritonsillar abscess, otitis media, sinusitis, impetigo or cellulitis) and reconsultation with new or unresolving symptoms within one month. RESULTS: Complications were assessed reliably (inter-rater κ=0.95). 1.3% (177/13,445) of participants developed complications overall and 14.2% (1889/13,288) reconsulted with new or unresolving symptoms. Independent predictors of complications were severe tonsillar inflammation (documented among 13.0% (1652/12,717); odds ratio 1.92, 95% confidence interval 1.28 to 2.89) and severe earache (5% (667/13,323); 3.02, 1.91 to 4.76), but the model including both variables had modest prognostic utility (bootstrapped area under the receiver operator curve 0.61, 0.57 to 0.65), and 70% of complications (124/177) occurred when neither was present. Clinical prediction rules for bacterial infection (Centor criteria and FeverPAIN) also predicted complications, but predictive values were also poor and most complications occurred with low scores (67% (118/175) scoring ≤ 2 for Centor; 126/173 (73%) scoring ≤ 2 for FeverPAIN). Previous medical problems, sex, temperature, and muscle aches were independently but weakly associated with reconsultation with new or unresolving symptoms. CONCLUSION: Important suppurative complications after an episode of acute sore throat in primary care are uncommon. History and examination and scores to predict bacterial infection cannot usefully identify those who will develop complications. Clinicians will need to rely on strategies such as safety netting or delayed prescription in managing the uncertainty and low risk of complications.


Asunto(s)
Absceso/microbiología , Dolor de Oído/microbiología , Faringitis/complicaciones , Atención Primaria de Salud , Tonsilitis/microbiología , Enfermedad Aguda , Adolescente , Adulto , Antibacterianos/uso terapéutico , Área Bajo la Curva , Celulitis (Flemón)/microbiología , Femenino , Humanos , Impétigo/microbiología , Masculino , Persona de Mediana Edad , Visita a Consultorio Médico/estadística & datos numéricos , Otitis Media Supurativa/microbiología , Tonsila Palatina , Faringitis/tratamiento farmacológico , Estudios Prospectivos , Curva ROC , Sinusitis/microbiología , Adulto Joven
7.
BMJ Case Rep ; 20102010 Nov 02.
Artículo en Inglés | MEDLINE | ID: mdl-22791782

RESUMEN

An elderly gentleman presented to hospital with recurrent blackout episodes consistent with syncope and a 3-month history of right ear pain. Significant postural hypotension was recorded. White cell count and C reactive protein were elevated. MRI of the head and neck revealed a soft tissue abnormality in the right nasopharynx and base of skull. Tissue biopsies were obtained and microbiology specimens revealed a mixed growth of pseudomonas and diphtheroids. There was no histological evidence of malignancy. A diagnosis of skull base infection was made. Infective involvement of the carotid sinus was considered to be the cause of the recurrent syncope and postural hypotension. The patient responded well to a 12-week course of intravenous meropenem. Inflammatory markers returned to normal and a repeat MRI after 3 months of treatment showed significant resolution of infection. The syncopal episodes and orthostatic hypotension resolved in parallel with treatment of infection.


Asunto(s)
Dolor Crónico/microbiología , Difteria/diagnóstico , Dolor de Oído/microbiología , Infecciones por Pseudomonas/diagnóstico , Síncope/microbiología , Anciano de 80 o más Años , Difteria/complicaciones , Humanos , Masculino , Infecciones por Pseudomonas/complicaciones , Recurrencia , Base del Cráneo
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