Detalhe da pesquisa
1.
Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 2.
J Biol Chem
; 299(2): 102873, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36621625
2.
Carcinogenic and neurotoxic risks of acrylamide consumed through bread, kaak, toast, and crackers among the Lebanese Population.
Regul Toxicol Pharmacol
; 132: 105192, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35654311
3.
Exploring links between 2-oxoglutarate-dependent oxygenases and Alzheimer's disease.
Alzheimers Dement
; 18(12): 2637-2668, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35852137
4.
Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii.
J Biol Chem
; 295(49): 16545-16561, 2020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32934009
5.
Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.
Nat Chem Biol
; 14(10): 988, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29950663
6.
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.
Nat Chem Biol
; 14(7): 688-695, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29915238
7.
Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.
Proc Natl Acad Sci U S A
; 114(18): 4667-4672, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28420789
8.
A Diverse View of Science to Catalyse Change.
Angew Chem Int Ed Engl
; 59(42): 18306-18310, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33448562
9.
Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding.
Chemistry
; 25(8): 2019-2024, 2019 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30427558
10.
Inhibition of a viral prolyl hydroxylase.
Bioorg Med Chem
; 27(12): 2405-2412, 2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737136
11.
Lysine-241 Has a Role in Coupling 2OG Turnover with Substrate Oxidation During KDM4-Catalysed Histone Demethylation.
Chembiochem
; 19(9): 917-921, 2018 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29443450
12.
Studies on the Substrate Selectivity of the Hypoxia-Inducible Factor Prolyl Hydroxylaseâ 2 Catalytic Domain.
Chembiochem
; 19(21): 2262-2267, 2018 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30144273
13.
Cyclobutanone Mimics of Intermediates in Metallo-ß-Lactamase Catalysis.
Chemistry
; 24(22): 5734-5737, 2018 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29250863
14.
19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-ß-Lactamase.
Angew Chem Int Ed Engl
; 56(14): 3862-3866, 2017 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28252254
15.
Interaction of Avibactam with Class B Metallo-ß-Lactamases.
Antimicrob Agents Chemother
; 60(10): 5655-62, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401561
16.
A Diverse View of Science to Catalyse Change.
J Am Chem Soc
; 142(34): 14393-14396, 2020 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32803980
17.
Comparison of Verona Integron-Borne Metallo-ß-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles.
Antimicrob Agents Chemother
; 60(3): 1377-84, 2015 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26666919
18.
Cyclic peptides target the aromatic cage of a PHD-finger reader domain to modulate epigenetic protein function.
Chem Sci
; 14(26): 7136-7146, 2023 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37416723
19.
Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans.
Sci Rep
; 12(1): 6065, 2022 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35410347
20.
Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors.
Nat Commun
; 13(1): 4785, 2022 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35970853