Detalhe da pesquisa
1.
Novel indolinone-tethered benzothiophenes as anti-tubercular agents against MDR/XDR M. tuberculosis: Design, synthesis, biological evaluation and in vivo pharmacokinetic study.
Bioorg Chem
; 143: 107009, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38070474
2.
Design and synthesis of benzo[b]thiophene-based hybrids as novel antitubercular agents against MDR/XDR Mycobacterium tuberculosis.
Arch Pharm (Weinheim)
; 357(2): e2300529, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37946574
3.
Isatin-pyrimidine hybrid derivatives as enoyl acyl carrier protein reductase (InhA) inhibitors against Mycobacterium tuberculosis.
Bioorg Chem
; 138: 106591, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37201321
4.
Design, synthesis, in vitro and in silico evaluation of novel substituted 1,2,4-triazole analogues as dual human VEGFR-2 and TB-InhA inhibitors.
Bioorg Chem
; 141: 106883, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37774433
5.
Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis.
J Enzyme Inhib Med Chem
; 38(1): 2250575, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37649381
6.
Targeting Mycobacterium tuberculosis: Synthesis, in vitro and in silico evaluation of novel N1 -(benzo[d]oxazol-2-yl)-N4 -arylidine compounds.
Arch Pharm (Weinheim)
; 356(8): e2300187, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37279375
7.
Promising anti-Helicobacter pylori and anti-inflammatory metabolites from unused parts of Phoenix dactylifera CV 'Zaghloul': in vitro and in silico study.
Pharm Biol
; 61(1): 657-665, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37092359
8.
Novel 2-arylthiazolidin-4-one-thiazole hybrids with potent activity against Mycobacterium tuberculosis.
Bioorg Chem
; 124: 105809, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447406
9.
Novel diaryl ether derivatives as InhA inhibitors: Design, synthesis and antimycobacterial activity.
Bioorg Chem
; 129: 106125, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36126606
10.
Design, synthesis and anti-Mycobacterium tuberculosis evaluation of new thiazolidin-4-one and thiazolo[3,2-a][1,3,5]triazine derivatives.
Bioorg Chem
; 124: 105807, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35487073
11.
Valorization of Pimenta racemosa Essential Oils and Extracts: GC-MS and LC-MS Phytochemical Profiling and Evaluation of Helicobacter pylori Inhibitory Activity.
Molecules
; 27(22)2022 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36432065
12.
Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis.
Molecules
; 27(24)2022 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36557937
13.
In silico study and biological screening of benzoquinazolines as potential antimicrobial agents against methicillin-resistant Staphylococcus aureus, carbapenem-resistant Klebsiella pneumoniae, and fluconazole-resistant Candida albicans.
Microb Pathog
; 160: 105157, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34454024
14.
Development of novel isatin-nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing-bacteria.
J Enzyme Inhib Med Chem
; 36(1): 384-393, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33406941
15.
Development of 3-methyl/3-(morpholinomethyl)benzofuran derivatives as novel antitumor agents towards non-small cell lung cancer cells.
J Enzyme Inhib Med Chem
; 36(1): 987-999, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33985397
16.
Development, synthesis, and biological evaluation of sulfonyl-α-l-amino acids as potential anti-Helicobacter pylori and IMPDH inhibitors.
Arch Pharm (Weinheim)
; 354(6): e2000385, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33576040
17.
Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity.
Bioorg Chem
; 104: 104316, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33022549
18.
Novel pyrazine based anti-tubercular agents: Design, synthesis, biological evaluation and in silico studies.
Bioorg Chem
; 96: 103610, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32028062
19.
Bio-Guided Fractionation of Prenylated Benzaldehyde Derivatives as Potent Antimicrobial and Antibiofilm from Ammi majus L. Fruits-Associated Aspergillus amstelodami.
Molecules
; 24(22)2019 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31739552
20.
Anti-Oral Pathogens of Tecoma stans (L.) and Cassia javanica (L.) Flower Volatile Oils in Comparison with Chlorhexidine in Accordance with Their Folk Medicinal Uses.
Medicina (Kaunas)
; 55(6)2019 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31238555