Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Is aging a "Retro"spective event?

Dasgupta, Nirmalya; Adams, Peter D.

Cell ; 186(2): 233-235, 2023 01 19.

Artigo em Inglês | MEDLINE | ID: mdl-36669469

2.

Cytoplasmic DNA: sources, sensing, and role in aging and disease.

Miller, Karl N; Victorelli, Stella G; Salmonowicz, Hanna; Dasgupta, Nirmalya; Liu, Tianhui; Passos, João F; Adams, Peter D.

Cell ; 184(22): 5506-5526, 2021 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-34715021

3.

Cellular Senescence: Defining a Path Forward.

Gorgoulis, Vassilis; Adams, Peter D; Alimonti, Andrea; Bennett, Dorothy C; Bischof, Oliver; Bishop, Cleo; Campisi, Judith; Collado, Manuel; Evangelou, Konstantinos; Ferbeyre, Gerardo; Gil, Jesús; Hara, Eiji; Krizhanovsky, Valery; Jurk, Diana; Maier, Andrea B; Narita, Masashi; Niedernhofer, Laura; Passos, João F; Robbins, Paul D; Schmitt, Clemens A; Sedivy, John; Vougas, Konstantinos; von Zglinicki, Thomas; Zhou, Daohong; Serrano, Manuel; Demaria, Marco.

Cell ; 179(4): 813-827, 2019 10 31.

Artigo em Inglês | MEDLINE | ID: mdl-31675495

4.

A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.

Lytle, Nikki K; Ferguson, L Paige; Rajbhandari, Nirakar; Gilroy, Kathryn; Fox, Raymond G; Deshpande, Anagha; Schürch, Christian M; Hamilton, Michael; Robertson, Neil; Lin, Wei; Noel, Pawan; Wartenberg, Martin; Zlobec, Inti; Eichmann, Micha; Galván, José A; Karamitopoulou, Eva; Gilderman, Tami; Esparza, Lourdes Adriana; Shima, Yutaka; Spahn, Philipp; French, Randall; Lewis, Nathan E; Fisch, Kathleen M; Sasik, Roman; Rosenthal, Sara Brin; Kritzik, Marcie; Von Hoff, Daniel; Han, Haiyong; Ideker, Trey; Deshpande, Aniruddha J; Lowy, Andrew M; Adams, Peter D; Reya, Tannishtha.

Cell ; 177(3): 572-586.e22, 2019 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-30955884

5.

Apoptotic stress causes mtDNA release during senescence and drives the SASP.

Victorelli, Stella; Salmonowicz, Hanna; Chapman, James; Martini, Helene; Vizioli, Maria Grazia; Riley, Joel S; Cloix, Catherine; Hall-Younger, Ella; Machado Espindola-Netto, Jair; Jurk, Diana; Lagnado, Anthony B; Sales Gomez, Lilian; Farr, Joshua N; Saul, Dominik; Reed, Rebecca; Kelly, George; Eppard, Madeline; Greaves, Laura C; Dou, Zhixun; Pirius, Nicholas; Szczepanowska, Karolina; Porritt, Rebecca A; Huang, Huijie; Huang, Timothy Y; Mann, Derek A; Masuda, Claudio Akio; Khosla, Sundeep; Dai, Haiming; Kaufmann, Scott H; Zacharioudakis, Emmanouil; Gavathiotis, Evripidis; LeBrasseur, Nathan K; Lei, Xue; Sainz, Alva G; Korolchuk, Viktor I; Adams, Peter D; Shadel, Gerald S; Tait, Stephen W G; Passos, João F.

Nature ; 622(7983): 627-636, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37821702

6.

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence.

Vizioli, Maria Grazia; Liu, Tianhui; Miller, Karl N; Robertson, Neil A; Gilroy, Kathryn; Lagnado, Anthony B; Perez-Garcia, Arantxa; Kiourtis, Christos; Dasgupta, Nirmalya; Lei, Xue; Kruger, Patrick J; Nixon, Colin; Clark, William; Jurk, Diana; Bird, Thomas G; Passos, João F; Berger, Shelley L; Dou, Zhixun; Adams, Peter D.

Genes Dev ; 34(5-6): 428-445, 2020 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-32001510

7.

Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence.

Sen, Payel; Lan, Yemin; Li, Catherine Y; Sidoli, Simone; Donahue, Greg; Dou, Zhixun; Frederick, Brian; Chen, Qijun; Luense, Lacey J; Garcia, Benjamin A; Dang, Weiwei; Johnson, F Bradley; Adams, Peter D; Schultz, David C; Berger, Shelley L.

Mol Cell ; 73(4): 684-698.e8, 2019 02 21.

Artigo em Inglês | MEDLINE | ID: mdl-30773298

8.

Transcriptional control of leukemogenesis by the chromatin reader SGF29.

Barbosa, Karina; Deshpande, Anagha; Perales, Marlenne; Xiang, Ping; Murad, Rabi; Pramod, Akula Bala; Minkina, Anna; Robertson, Neil; Schischlik, Fiorella; Lei, Xue; Sun, Younguk; Brown, Adam; Amend, Diana; Jeremias, Irmela; Doench, John G; Humphries, R Keith; Ruppin, Eytan; Shendure, Jay; Mali, Prashant; Adams, Peter D; Deshpande, Aniruddha J.

Blood ; 143(8): 697-712, 2024 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-38048593

9.

DNA Methylation Clocks in Aging: Categories, Causes, and Consequences.

Field, Adam E; Robertson, Neil A; Wang, Tina; Havas, Aaron; Ideker, Trey; Adams, Peter D.

Mol Cell ; 71(6): 882-895, 2018 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-30241605

10.

Post-translational modifications of ATG8 proteins - an emerging mechanism of autophagy control.

Nieto-Torres, Jose L; Zaretski, Sviatlana; Liu, Tianhui; Adams, Peter D; Hansen, Malene.

J Cell Sci ; 136(16)2023 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-37589340

11.

Hematopoiesis: a BETter understanding.

Dasgupta, Nirmalya; Adams, Peter D.

EMBO Rep ; 24(10): e57927, 2023 Oct 09.

Artigo em Inglês | MEDLINE | ID: mdl-37650879

12.

Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP.

Victorelli, Stella; Salmonowicz, Hanna; Chapman, James; Martini, Helene; Vizioli, Maria Grazia; Riley, Joel S; Cloix, Catherine; Hall-Younger, Ella; Machado Espindola-Netto, Jair; Jurk, Diana; Lagnado, Anthony B; Sales Gomez, Lilian; Farr, Joshua N; Saul, Dominik; Reed, Rebecca; Kelly, George; Eppard, Madeline; Greaves, Laura C; Dou, Zhixun; Pirius, Nicholas; Szczepanowska, Karolina; Porritt, Rebecca A; Huang, Huijie; Huang, Timothy Y; Mann, Derek A; Masuda, Claudio Akio; Khosla, Sundeep; Dai, Haiming; Kaufmann, Scott H; Zacharioudakis, Emmanouil; Gavathiotis, Evripidis; LeBrasseur, Nathan K; Lei, Xue; Sainz, Alva G; Korolchuk, Viktor I; Adams, Peter D; Shadel, Gerald S; Tait, Stephen W G; Passos, João F.

Nature ; 625(7995): E15, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38168624

13.

Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.

Maddocks, Oliver D K; Labuschagne, Christiaan F; Adams, Peter D; Vousden, Karen H.

Mol Cell ; 61(2): 210-21, 2016 Jan 21.

Artigo em Inglês | MEDLINE | ID: mdl-26774282

14.

MLL1 is essential for the senescence-associated secretory phenotype.

Capell, Brian C; Drake, Adam M; Zhu, Jiajun; Shah, Parisha P; Dou, Zhixun; Dorsey, Jean; Simola, Daniel F; Donahue, Greg; Sammons, Morgan; Rai, Taranjit Singh; Natale, Christopher; Ridky, Todd W; Adams, Peter D; Berger, Shelley L.

Genes Dev ; 30(3): 321-36, 2016 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-26833731

15.

Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction.

Victorelli, Stella; Lagnado, Anthony; Halim, Jessica; Moore, Will; Talbot, Duncan; Barrett, Karen; Chapman, James; Birch, Jodie; Ogrodnik, Mikolaj; Meves, Alexander; Pawlikowski, Jeff S; Jurk, Diana; Adams, Peter D; van Heemst, Diana; Beekman, Marian; Slagboom, P Eline; Gunn, David A; Passos, João F.

EMBO J ; 38(23): e101982, 2019 12 02.

Artigo em Inglês | MEDLINE | ID: mdl-31633821

16.

Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.

Anderson, Rhys; Lagnado, Anthony; Maggiorani, Damien; Walaszczyk, Anna; Dookun, Emily; Chapman, James; Birch, Jodie; Salmonowicz, Hanna; Ogrodnik, Mikolaj; Jurk, Diana; Proctor, Carole; Correia-Melo, Clara; Victorelli, Stella; Fielder, Edward; Berlinguer-Palmini, Rolando; Owens, Andrew; Greaves, Laura C; Kolsky, Kathy L; Parini, Angelo; Douin-Echinard, Victorine; LeBrasseur, Nathan K; Arthur, Helen M; Tual-Chalot, Simon; Schafer, Marissa J; Roos, Carolyn M; Miller, Jordan D; Robertson, Neil; Mann, Jelena; Adams, Peter D; Tchkonia, Tamara; Kirkland, James L; Mialet-Perez, Jeanne; Richardson, Gavin D; Passos, João F.

EMBO J ; 38(5)2019 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-30737259

17.

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML.

Chen, Bo-Rui; Deshpande, Anagha; Barbosa, Karina; Kleppe, Maria; Lei, Xue; Yeddula, Narayana; Vela, Pablo Sánchez; Campos, Alexandre Rosa; Wechsler-Reya, Robert J; Bagchi, Anindya; Meshinchi, Soheil; Eaves, Connie; Jeremias, Irmela; Haferlach, Torsten; Frank, David A; Ronai, Ze'ev; Chanda, Sumit; Armstrong, Scott A; Adams, Peter D; Levine, Ross L; Deshpande, Aniruddha J.

Blood ; 137(24): 3403-3415, 2021 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-33690798

18.

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

Dou, Zhixun; Ghosh, Kanad; Vizioli, Maria Grazia; Zhu, Jiajun; Sen, Payel; Wangensteen, Kirk J; Simithy, Johayra; Lan, Yemin; Lin, Yanping; Zhou, Zhuo; Capell, Brian C; Xu, Caiyue; Xu, Mingang; Kieckhaefer, Julia E; Jiang, Tianying; Shoshkes-Carmel, Michal; Tanim, K M Ahasan Al; Barber, Glen N; Seykora, John T; Millar, Sarah E; Kaestner, Klaus H; Garcia, Benjamin A; Adams, Peter D; Berger, Shelley L.

Nature ; 550(7676): 402-406, 2017 10 19.

Artigo em Inglês | MEDLINE | ID: mdl-28976970

19.

HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.

Rai, Taranjit Singh; Cole, John J; Nelson, David M; Dikovskaya, Dina; Faller, William J; Vizioli, Maria Grazia; Hewitt, Rachael N; Anannya, Orchi; McBryan, Tony; Manoharan, Indrani; van Tuyn, John; Morrice, Nicholas; Pchelintsev, Nikolay A; Ivanov, Andre; Brock, Claire; Drotar, Mark E; Nixon, Colin; Clark, William; Sansom, Owen J; Anderson, Kurt I; King, Ayala; Blyth, Karen; Adams, Peter D.

Genes Dev ; 28(24): 2712-25, 2014 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-25512559

20.

The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection.

McFarlane, Steven; Orr, Anne; Roberts, Ashley P E; Conn, Kristen L; Iliev, Victor; Loney, Colin; da Silva Filipe, Ana; Smollett, Katherine; Gu, Quan; Robertson, Neil; Adams, Peter D; Rai, Taranjit Singh; Boutell, Chris.

PLoS Pathog ; 15(3): e1007667, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30901352

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