Detalhe da pesquisa
1.
Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis.
J Cell Sci
; 133(5)2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31780579
2.
Development of a covalent inhibitor of gut bacterial bile salt hydrolases.
Nat Chem Biol
; 16(3): 318-326, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32042200
3.
N1-Benzyl Tryptamine Pan-SHIP1/2 Inhibitors: Synthesis and Preliminary Biological Evaluation as Anti-Tumor Agents.
Molecules
; 27(23)2022 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36500543
4.
Ester Formation via Symbiotic Activation Utilizing Trichloroacetimidate Electrophiles.
J Org Chem
; 84(12): 7871-7882, 2019 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31117564
5.
Dialkylation of Indoles with Trichloroacetimidates to Access 3,3-Disubstituted Indolenines.
Molecules
; 24(22)2019 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31731742
6.
Rearrangement of Benzylic Trichloroacetimidates to Benzylic Trichloroacetamides.
J Org Chem
; 82(7): 3982-3989, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28323428
7.
Synthesis and initial evaluation of quinoline-based inhibitors of the SH2-containing inositol 5'-phosphatase (SHIP).
Bioorg Med Chem Lett
; 25(22): 5344-8, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26453006
8.
A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteria.
Nat Microbiol
; 7(9): 1404-1418, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35982310
9.
Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury.
Sci Adv
; 8(34): eabo2794, 2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36026454
10.
A Gut-Restricted Lithocholic Acid Analog as an Inhibitor of Gut Bacterial Bile Salt Hydrolases.
ACS Chem Biol
; 16(8): 1401-1412, 2021 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34279901
11.
A microbial metabolite remodels the gut-liver axis following bariatric surgery.
Cell Host Microbe
; 29(3): 408-424.e7, 2021 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33434516
12.
A selective gut bacterial bile salt hydrolase alters host metabolism.
Elife
; 72018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30014852
13.
Synthesis of 3,3'-Disubstituted Indolenines Utilizing the Lewis Acid Catalyzed Alkylation of 2,3-Disubstituted Indoles with Trichloroacetimidates.
Synlett
; 28(17): 2335-2339, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29033500
14.
Lewis Acid Catalyzed Displacement of Trichloroacetimidates in the Synthesis of Functionalized Pyrroloindolines.
Org Lett
; 18(16): 4100-3, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27486831