Detalhe da pesquisa
1.
Suppression of Kv3.3 channels by antisense oligonucleotides reverses biochemical effects and motor impairment in spinocerebellar ataxia type 13 mice.
FASEB J
; 35(12): e22053, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34820911
2.
RAGE Enhances TLR Responses through Binding and Internalization of RNA.
J Immunol
; 197(10): 4118-4126, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798148
3.
Role of Toll-like receptors in the pathogenesis of dystrophin-deficient skeletal and heart muscle.
Hum Mol Genet
; 23(10): 2604-17, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24368419
4.
Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.
J Immunol
; 193(7): 3257-61, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25187660
5.
Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9.
Nucleic Acids Res
; 41(6): 3947-61, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23396449
6.
Design of synthetic oligoribonucleotide-based agonists of Toll-like receptor 3 and their immune response profiles in vitro and in vivo.
Org Biomol Chem
; 11(6): 1049-58, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23292214
7.
Introduction and History of the Chemistry of Nucleic Acids Therapeutics.
Methods Mol Biol
; 2434: 3-31, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213007
8.
Developing antisense oligonucleotides for a TECPR2 mutation-induced, ultra-rare neurological disorder using patient-derived cellular models.
Mol Ther Nucleic Acids
; 29: 189-203, 2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35860385
9.
PKA knockdown enhances cell killing in response to radiation and androgen deprivation.
Int J Cancer
; 128(4): 962-73, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20960462
10.
Synthesis and immunological activities of novel Toll-like receptor 7 and 8 agonists.
Cell Immunol
; 270(2): 126-34, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21570062
11.
The Evolution of Antisense Oligonucleotide Chemistry-A Personal Journey.
Biomedicines
; 9(5)2021 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34063675
12.
Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti-PD-1 Refractory Melanoma.
Cancer Discov
; 11(8): 1996-2013, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33707233
13.
Synthesis and immunological activities of novel agonists of toll-like receptor 9.
Cell Immunol
; 263(1): 105-13, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20381019
14.
Peptide conjugation at the 5'-end of oligodeoxynucleotides abrogates toll-like receptor 9-mediated immune stimulatory activity.
Bioconjug Chem
; 21(1): 39-45, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20020767
15.
Treatment of mammary carcinomas in HER-2 transgenic mice through combination of genetic vaccine and an agonist of Toll-like receptor 9.
Clin Cancer Res
; 15(5): 1575-84, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19240169
16.
Coadministration of telomerase genetic vaccine and a novel TLR9 agonist in nonhuman primates.
Mol Ther
; 17(10): 1804-13, 2009 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19623161
17.
RNA Therapeutics Are Stepping Out of the Maze.
Trends Mol Med
; 26(12): 1061-1064, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32988738
18.
Antisense MDM2 enhances E2F1-induced apoptosis and the combination sensitizes androgen-sensitive [corrected] and androgen-insensitive [corrected] prostate cancer cells to radiation.
Mol Cancer Res
; 6(11): 1742-54, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010821
19.
Synthetic oligoribonucleotides-containing secondary structures act as agonists of Toll-like receptors 7 and 8.
Biochem Biophys Res Commun
; 386(3): 443-8, 2009 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19523922
20.
Synthetic oligoribonucleotides containing arabinonucleotides act as agonists of TLR7 and 8.
Bioorg Med Chem Lett
; 19(7): 2044-7, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19269175