Detalhe da pesquisa
1.
Effects of somatostatin receptor type 2 antagonism during insulin-induced hypoglycaemia in male rats with prediabetes.
Diabetes Obes Metab
; 25(6): 1547-1556, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36734462
2.
ZT-01: A novel somatostatin receptor 2 antagonist for restoring the glucagon response to hypoglycaemia in type 1 diabetes.
Diabetes Obes Metab
; 24(5): 908-917, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35060297
3.
Phosphorylation of murine double minute-2 on Ser166 is downstream of VEGF-A in exercised skeletal muscle and regulates primary endothelial cell migration and FoxO gene expression.
FASEB J
; 30(3): 1120-34, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26578686
4.
The Vascular Endothelial Growth Factor-A phosphorylates Murine Double Minute-2 on its Serine 166 via the Extracellular Signal-Regulated Kinase 1/2 and p90 Ribosomal S6 Kinase in primary human endothelial cells.
Biochem Biophys Res Commun
; 478(4): 1548-54, 2016 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27591897
5.
Evaluating the effectiveness of a novel somatostatin receptor 2 antagonist, ZT-01, for hypoglycemia prevention in a rodent model of type 2 diabetes.
Front Pharmacol
; 15: 1302015, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38510652
6.
Somatostatin Receptor Antagonism Reverses Glucagon Counterregulatory Failure in Recurrently Hypoglycemic Male Rats.
Endocrinology
; 162(12)2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34477204
7.
Hyperglycaemia correlates with skeletal muscle capillary regression and is associated with alterations in the murine double minute-2/forkhead box O1/thrombospondin-1 pathway in type 1 diabetic BioBreeding rats.
Diab Vasc Dis Res
; 16(1): 28-37, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30360646
8.
The effects of voluntary exercise and prazosin on capillary rarefaction and metabolism in streptozotocin-induced diabetic male rats.
J Appl Physiol (1985)
; 122(3): 492-502, 2017 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27932675
9.
Novel perspective: exercise training stimulus triggers the expression of the oncoprotein human double minute-2 in human skeletal muscle.
Physiol Rep
; 1(2): e00028, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24303114