Detalhe da pesquisa
1.
The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer.
Br J Cancer
; 128(12): 2326-2337, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37076563
2.
Correction: The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer.
Br J Cancer
; 130(5): 892, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38355841
3.
Suppressors of superoxide production from mitochondrial complex III.
Nat Chem Biol
; 11(11): 834-6, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26368590
4.
Integrated CRISPR screening and drug profiling identifies combination opportunities for EGFR, ALK, and BRAF/MEK inhibitors.
Cell Rep
; 42(4): 112297, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36961816
5.
Development of a quantitative 96-well method to image glycogen storage in primary rat hepatocytes.
Mol Cell Biochem
; 341(1-2): 73-8, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20333445
6.
Structure-guided combination therapy to potently improve the function of mutant CFTRs.
Nat Med
; 24(11): 1732-1742, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297908
7.
Dual ALK and CDK4/6 Inhibition Demonstrates Synergy against Neuroblastoma.
Clin Cancer Res
; 23(11): 2856-2868, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27986745
8.
An Automatic Quality Control Pipeline for High-Throughput Screening Hit Identification.
J Biomol Screen
; 21(8): 832-41, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27313114
9.
Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
Cell Metab
; 24(4): 582-592, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27667666
10.
Glucose-stimulated oscillations in free cytosolic ATP concentration imaged in single islet beta-cells: evidence for a Ca2+-dependent mechanism.
Diabetes
; 51 Suppl 1: S162-70, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11815476
11.
Development and validation of a simple cell-based fluorescence assay for dipeptidyl peptidase 1 (DPP1) activity.
J Biomol Screen
; 16(1): 36-43, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21088147
12.
Investigations into the liver effects of ximelagatran using high content screening of primary human hepatocyte cultures.
Expert Opin Drug Saf
; 7(4): 351-65, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18613800
13.
Glucose-stimulated insulin secretion does not require activation of pyruvate dehydrogenase: impact of adenovirus-mediated overexpression of PDH kinase and PDH phosphate phosphatase in pancreatic islets.
Biochem Biophys Res Commun
; 291(4): 1081-8, 2002 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-11866475
14.
Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: evidence for ATP-independent control of ATP-sensitive K(+) channels.
J Physiol
; 544(2): 429-45, 2002 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12381816
15.
Involvement of conventional kinesin in glucose-stimulated secretory granule movements and exocytosis in clonal pancreatic beta-cells.
J Cell Sci
; 115(Pt 21): 4177-89, 2002 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12356920
16.
Dynamics of glucose-induced membrane recruitment of protein kinase C beta II in living pancreatic islet beta-cells.
J Biol Chem
; 277(40): 37702-10, 2002 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12149258
17.
Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells.
Am J Physiol Endocrinol Metab
; 285(2): E262-71, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12644449