Detalhe da pesquisa
1.
Effect of ASP8062 on morphine self-administration and morphine-induced respiratory suppression in monkeys.
J Pharmacol Sci
; 151(4): 171-176, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36925215
2.
Synthesis and pharmacological evaluation of optically pure, novel carbonyl guanidine derivatives as dual 5-HT2B and 5-HT7 receptor antagonists.
Bioorg Med Chem
; 22(21): 6026-38, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25281269
3.
Synthesis and structure-activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists. Part 2.
Bioorg Med Chem
; 22(15): 4323-37, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24916029
4.
Synthesis and structure-activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists.
Bioorg Med Chem
; 21(24): 7841-52, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24189186
5.
A novel GABAB receptor positive allosteric modulator, ASP8062, exerts analgesic effects in a rat model of fibromyalgia.
Eur J Pharmacol
; 865: 172750, 2019 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31647906
6.
Effects of serotonin 5-HT(3) receptor antagonists on CRF-induced abnormal colonic water transport and defecation in rats.
Eur J Pharmacol
; 587(1-3): 281-4, 2008 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18456254
7.
Effect of ramosetron on conditioned emotional stress-induced colonic dysfunction as a model of irritable bowel syndrome in rats.
Eur J Pharmacol
; 573(1-3): 190-5, 2007 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17658508
8.
Inhibitory effects of ramosetron, a potent and selective 5-HT3-receptor antagonist, on conditioned fear stress-induced abnormal defecation and normal defecation in rats: comparative studies with antidiarrheal and spasmolytic agents.
J Pharmacol Sci
; 106(2): 264-70, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18296863
9.
Evaluation of the pharmacological profile of ramosetron, a novel therapeutic agent for irritable bowel syndrome.
J Pharmacol Sci
; 104(3): 263-73, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17652911
10.
[Pharmacological and clinical profile of ramosetron hydrochloride (Irribow), a novel therapeutic agent for irritable bowel syndrome with diarrhea].
Nihon Yakurigaku Zasshi
; 133(5): 281-91, 2009 May.
Artigo
em Japonês
| MEDLINE | ID: mdl-19443966
11.
New thiazole derivatives as potent and selective 5-hydroxytriptamine 3 (5-HT3) receptor agonists for the treatment of constipation.
Bioorg Med Chem
; 11(7): 1493-502, 2003 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-12628674