Detalhe da pesquisa
1.
The roles of structural dynamics in the cellular functions of RNAs.
Nat Rev Mol Cell Biol
; 20(8): 474-489, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31182864
2.
Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity.
Cell
; 163(3): 746-58, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26496612
3.
Hierarchy of RNA functional dynamics.
Annu Rev Biochem
; 83: 441-66, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24606137
4.
RNA conformational propensities determine cellular activity.
Nature
; 617(7962): 835-841, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37198487
5.
DNA mismatches reveal conformational penalties in protein-DNA recognition.
Nature
; 587(7833): 291-296, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33087930
6.
NMR measurements of transient low-populated tautomeric and anionic Watson-Crick-like G·T/U in RNA:DNA hybrids: implications for the fidelity of transcription and CRISPR/Cas9 gene editing.
Nucleic Acids Res
; 52(5): 2672-2685, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38281263
7.
Turing, von Neumann, and the computational architecture of biological machines.
Proc Natl Acad Sci U S A
; 120(25): e2220022120, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37307461
8.
Dynamic basis for dAâ¢dGTP and dAâ¢d8OGTP misincorporation via Hoogsteen base pairs.
Nat Chem Biol
; 19(7): 900-910, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37095237
9.
Probing Watson-Crick and Hoogsteen base pairing in duplex DNA using dynamic nuclear polarization solid-state NMR spectroscopy.
Proc Natl Acad Sci U S A
; 119(30): e2200681119, 2022 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857870
10.
Structural basis for impaired 5' processing of a mutant tRNA associated with defects in neuronal homeostasis.
Proc Natl Acad Sci U S A
; 119(10): e2119529119, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35238631
11.
Measuring thermodynamic preferences to form non-native conformations in nucleic acids using ultraviolet melting.
Proc Natl Acad Sci U S A
; 119(24): e2112496119, 2022 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35671421
12.
Dynamic basis for dGâ¢dT misincorporation via tautomerization and ionization.
Nature
; 554(7691): 195-201, 2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29420478
13.
Author Correction: RNA conformational propensities determine cellular activity.
Nature
; 618(7967): E35, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37296211
14.
Kinetic Resolution of the Atomic 3D Structures Formed by Ground and Excited Conformational States in an RNA Dynamic Ensemble.
J Am Chem Soc
; 145(42): 22964-22978, 2023 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37831584
15.
Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem-loop RNAs and their implications for functional cellular assays.
RNA
; 27(1): 12-26, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33028652
16.
Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA.
Nucleic Acids Res
; 49(21): 12540-12555, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34792150
17.
2'-O-Methylation can increase the abundance and lifetime of alternative RNA conformational states.
Nucleic Acids Res
; 48(21): 12365-12379, 2020 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33104789
18.
Hoogsteen base pairs increase the susceptibility of double-stranded DNA to cytotoxic damage.
J Biol Chem
; 295(47): 15933-15947, 2020 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913127
19.
Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes.
Nature
; 519(7543): 315-20, 2015 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25762137
20.
Dynamic ensemble of HIV-1 RRE stem IIB reveals non-native conformations that disrupt the Rev-binding site.
Nucleic Acids Res
; 47(13): 7105-7117, 2019 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31199872