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1.
J Asthma ; 51(1): 51-7, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24024792

RESUMO

OBJECTIVES: The aim of this study was to characterize the current practice of asthma among general practitioners (GPs) in Lebanon. METHODS: Out of 2450 Lebanese registered GPs, a representative sample of 330 were stratified by region to fill out the questionnaire constructed on the basis of surveys developed mainly by the Chicago Asthma Surveillance Initiative Report Team in newly moderate persistent asthma patients aged 5 years and above. The questionnaire included information about ascertaining diagnostic techniques, pharmacotherapeutic approaches, formal patient education program; asthma related continuing medical education and asthma practice guidelines. RESULTS: Totally, 302 completed the questionnaire achieving a response rate of 91.5%. Chest radiography was the most commonly used diagnostic test (98%), while stain for eosinophilia was the less commonly used (7.9%). For clinical monitoring, cough and wheezing (98.7%) were mostly assessed. Short acting inhaled ß2-agonists were often the most prescribed (94.3%) followed by inhaled corticosteroids (87.4%) then by long acting ß-agonist (LABA) and theophylline (27.5% and 20.9%, respectively). Moreover, 10% of GPs provided formal asthma education program, 72.2% attended professional education and 65% adopted guidelines. CONCLUSION: Based on current international guidelines, the overall Lebanese GPs practice of asthma management is not at an acceptable standard. Therefore, it is recommended to improve monitoring parameters, implement the asthma guidelines nationally and improve patient education.


Assuntos
Asma/tratamento farmacológico , Clínicos Gerais/normas , Padrões de Prática Médica/normas , Adulto , Antiasmáticos/uso terapêutico , Asma/diagnóstico , Técnicas de Diagnóstico do Sistema Respiratório , Feminino , Humanos , Líbano , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários
2.
J Clin Nurs ; 22(21-22): 3153-9, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23786600

RESUMO

AIMS AND OBJECTIVES: To investigate the level of job satisfaction and the impact of personal characteristics and work environment on job satisfaction among nurses. BACKGROUND: Job satisfaction among nurses is of paramount importance to providers of health care because satisfied nurses appear to be endowed with the physical and emotional dexterity and the effort needed to perform their tasks that will enhance the quality of care provided to the patient. DESIGN: A cross-sectional survey. METHODS: The study included nurses of both genders with at least one year of nursing experience, serving in all shifts of various clinical settings (n = 178 nurses). A modified version of measure of nurses' job satisfaction, developed by Whitley and Putzier, was used to assess the effect of personal characteristics profile and work environment on job satisfaction. RESULTS: A total of 140 nurses were (response rate = 78·7%) entered into final data analysis. The study showed that 111 participants (79·3%) were significantly satisfied in their current jobs. Furthermore, 65 nurses (46·4%) were not satisfied with their salaries, and almost half the nurses were not pleased with the nurse/patient ratio, autonomy and enough time to discuss problems with staff. CONCLUSION: This study revealed that almost 50% of nurses are overworked, are unsatisfied with their salaries, and have limited autonomy and inadequate communication with superiors. Strategies must be formulated by hospital and government authorities to decrease workload and empower nurses in controlling their practice in order to retain nurses in their jobs. RELEVANCE TO CLINICAL PRACTICE: The management must provide positive leadership and understand the local issues that affect nurses in order to enhance retaining and avoid shortage. This can be reflected positively on nursing clinical practice and ultimately patient health status.


Assuntos
Satisfação no Emprego , Recursos Humanos de Enfermagem Hospitalar/psicologia , Centros de Atenção Terciária , Adulto , Estudos Transversais , Feminino , Humanos , Líbano , Masculino , Inquéritos e Questionários , Recursos Humanos , Adulto Jovem
3.
Neurosciences (Riyadh) ; 18(2): 143-6, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23545612

RESUMO

OBJECTIVE: To compare the effectiveness of 2 novel antiepileptic drugs, topiramate and levetiracetam, as a second line treatment for infantile spasm when oral steroids fail. METHODS: Forty infants under 2 years with clinically- and EEG-proven infantile spasms that did not respond to prednisone (2mg/kg/day in 2 divided doses) were recruited and randomized into 2 groups. They were randomly assigned to either topiramate (group 1; 1mg/kg/day for 3 days then increased by 1mg/kg/day every third day up to 6mg/kg/day) or levetiracetam (group 2; 10mg/kg/day for 5 days and then increased by 10mg/kg/day every 5 days up to 60mg/kg/day). The study was conducted in the Pediatric Neurology Department at the National Neuroscience Institute of King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia between January 2008 and December 2010. RESULTS: Of the 20 patients included in the final data analysis, 11 (55%) were administered topiramate and 9 (45%) levetiracetam. Eighteen patients did not respond to the first drug, and subsequently to the other drug when crossed-over. Two patients with infantile spasm responded to either one drug without crossover. Their EEGs improved with time. CONCLUSION: The present study demonstrated the ineffectiveness of topiramate and levetiracetam suggesting current treatment modalities are grossly inadequate underscoring the urgent need for more research efforts to overcome current deficiencies. Two patients with cryptogenic infantile spasm responded to treatment suggesting the potential for treatment of such patients with these 2 drugs, and merits further multicenter investigation.


Assuntos
Anticonvulsivantes/uso terapêutico , Frutose/análogos & derivados , Piracetam/análogos & derivados , Prednisona/uso terapêutico , Espasmos Infantis/tratamento farmacológico , Estudos Cross-Over , Esquema de Medicação , Quimioterapia Combinada , Feminino , Frutose/uso terapêutico , Humanos , Lactente , Recém-Nascido , Levetiracetam , Masculino , Piracetam/uso terapêutico , Estudos Prospectivos , Retratamento , Topiramato , Falha de Tratamento
4.
Croat Med J ; 52(5): 637-43, 2011 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-21990082

RESUMO

AIM: To assess parental perceptions and beliefs about asthma in children. METHODS: We invited 6000 children aged 3 to 15 years from different schools in Lebanon to participate in the study from September 2007 to May 2008. In the first phase, in order to determine the prevalence of asthma in children, parents of all participating children filled out a small questionnaire. In the second phase, only parents of children with asthma filled out a detailed questionnaire about their perceptions of asthma. RESULTS: Phase I included parents of 4051 children, 574 (14%) of whom had asthma and were recruited to phase II. Out of these, 389 parents entered the final data analysis. Around 54% of parents believed that asthma was hereditary and 7% believed it was contagious. When asked about triggering factors, 51% stated virus infection, 75% dust, and 17% food. Sixty percent of children with asthma lived with someone who smoked. Sixty-seven percent of parents believed that herbs had a role in asthma treatment and only 49% received asthma education. There was a significant difference in education level (P=0.01) between the parents who denied the label of asthma (79%) and those who accepted it (21%). Sixty-seven percent of parents preferred oral over inhaler treatment, 48% believed inhalers were addictive, 56% worried about inhalers' side effects, and 76% worried about using inhaled corticosteroids. Significantly more parents from rural (53%) than from urban areas (38%) believed that inhalers were addictive (P=0.004). CONCLUSION: Parents of children with asthma had considerable misperceptions about the use of inhalers and the safety of inhaled corticosteroids. To improve asthma care in children, it is necessary to provide adequate education to parents.


Assuntos
Asma , Conhecimentos, Atitudes e Prática em Saúde , Pais/psicologia , Adolescente , Adulto , Criança , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Líbano , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários
5.
Saudi Med J ; 41(3): 296-303, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32114603

RESUMO

OBJECTIVES: To assess the knowledge, attitudes, and practices of adults regarding the implementation of calorie labeling in restaurants in Riyadh, Saudi Arabia. METHODS: This was a cross-sectional study of 1443 adults invited to complete a self-administered questionnaire consisting of 4 parts that assess demographics, knowledge, attitudes, and practices of mandatory menu labeling. The survey was conducted in all 5 regions of Riyadh. RESULTS: We entered 1265 surveys into final data analysis with a response rate of 88%. Of this, 1036 participants (82%) understood the meaning and values of calories, while 53% knew the average daily caloric intake. Regarding participants' attitudes, 1053 (83%) perceived the importance of calorie labeling and (88%) supported this policy. Approximately 50% (n=626) of the participants were significantly more likely to be influenced by the calorie labeling to place a healthier order. Married (p=0.050), educated (p less than 0.001), and higher monthly income (p less than 0.001) were significantly influenced to place a healthier restaurant order compared to their peers. CONCLUSION: Adults in Riyadh showed satisfactory knowledge, attitude, and practice since the implementation of this policy. Our findings showed that knowing the value of calories and average caloric intake had a significant positive influence for a healthier diet. This highlights the importance of menu labeling regulations campaigns for the public.


Assuntos
Dieta Saudável , Ingestão de Energia , Rotulagem de Alimentos , Comportamentos Relacionados com a Saúde , Conhecimentos, Atitudes e Prática em Saúde , Política Nutricional , Saúde Pública , Restaurantes , Adolescente , Adulto , Estudos Transversais , Escolaridade , Feminino , Promoção da Saúde , Humanos , Renda , Masculino , Estado Civil , Pessoa de Meia-Idade , Arábia Saudita , Inquéritos e Questionários , Adulto Jovem
6.
J Anesth ; 23(1): 143-6, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19234842

RESUMO

Patients with severe ankylosing spondylitis (AS) have difficulties in tracheal intubation. An 87-year-old man with severe AS was scheduled for Zenker diverticulum (ZD) excision. It was decided to proceed with combined bilateral cervical plexus blockade using a nerve stimulator. The surgery lasted about 3 h, with stable hemodynamics, ECG, and oxygen saturation. The use of a nerve stimulator-guided cervical block minimizes the risk of severe respiratory and/or airway compromise secondary to phrenic nerve or recurrent laryngeal nerve palsy, because it can elicit diaphragmatic muscle response, which helps to avoid the administration of local anesthetic directly to the area of the phrenic nerve, and guides correct needle placement. In conclusion, the nerve stimulatorguided bilateral cervical block in our ZD patient with AS was shown to be a safe and successful alternative anesthetic option.


Assuntos
Raquianestesia , Bloqueio Nervoso , Espondilite Anquilosante/complicações , Divertículo de Zenker/complicações , Divertículo de Zenker/cirurgia , Idoso de 80 Anos ou mais , Anestésicos Locais , Estimulação Elétrica , Eletrocardiografia , Hemodinâmica/fisiologia , Humanos , Masculino , Monitorização Intraoperatória , Oxigênio/sangue , Radiografia , Divertículo de Zenker/diagnóstico por imagem
7.
PLoS One ; 14(4): e0213938, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30978182

RESUMO

This study aimed to investigate physicians' and nurses' knowledge and attitudes toward advance directives (ADs) for cancer patients, which empower patients to take decisions on end-of-life needs if they lose their capacity to make medical decisions. A cross-sectional study was conducted using convenience sampling. The outcomes were responses to the knowledge and attitude questions, and the main outcome variables were the total scores for knowledge and attitudes toward ADs. This study included 281 physicians and nurses (60.5%). Most physicians were men (95, 80.5%), whereas most nurses were women (147, 86.5%). The mean (standard deviation; SD) total knowledge score was 6.8 (4.0) for physicians and 9.1 (3.0) for nurses (p < 0.001). There was a significant difference in the total knowledge score between nurses and physicians, with an adjusted mean difference of 1.54 (95% confidence interval [CI]; 0.08-2.97). Other significant independent predictors of knowledge of ADs were female sex (1.60, 95% CI; 0.27-3.13) and education level (master's versus bachelor's: 1.26, 95% CI; 0.30-2.33 and Ph.D. versus bachelor's: 2.22, 95% CI; 0.16-4.52). Nurses' attitudes appeared to be significantly more positive than those of physicians, and the mean total attitude score (SD) was 19.5 for nurses (6.2) and 15.1 (8.1) for physicians (p < 0.001). The adjusted mean difference (95% CI) for nurses versus physicians was 3.71 (0.57-6.98). All participants showed a high level of knowledge of ADs; however, nurses showed considerably more positive attitudes than physicians.


Assuntos
Diretivas Antecipadas/psicologia , Competência Clínica , Neoplasias/terapia , Enfermeiras e Enfermeiros/psicologia , Médicos/psicologia , Adulto , Atitude do Pessoal de Saúde , Estudos Transversais , Feminino , Humanos , Islamismo/psicologia , Masculino , Arábia Saudita , Adulto Jovem
8.
Saudi Med J ; 39(2): 191-196, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29436569

RESUMO

OBJECTIVES: To investigate the knowledge, attitudes practices and perceptions of clinicians concerning the conducting of clinical trials (CTs).  Methods: A cross-sectional study was conducted on clinicians at King Fahad Medical City, Riyadh, Saudi Arabia. Data were collected using a self-administered questionnaire which divided into 5 sections: Section 1 covered respondents' demographics. The other 4 sections explored respondents' knowledge, attitudes, perceptions and practice towards conducting CTs.  Results: A total of 316 clinicians completed the questionnaire. The majority were assistant consultants and consultants 125 (39.5%) and 108 (34.2%), respectively. One hundred sixty-nine (56%) respondents were not aware of the Declaration of Helsinki at all. Two hundred seventy-five (88.4%) respondents expressed interest in conducting CTs and 61.7% and participants showed their willingness to facilitate and assist in CTs conducted by other clinicians. Moreover, 112 (35.9%) respondents participated in CTs previously. Regarding the disadvantages in conducting CTs, participants indicated that the paperwork was complicated and they believed that they might lose patients from their clinical practice once they are recruited in CTs. Lack of research protected time for clinicians 295 (97.7%), and a shortage of clinical research coordinators 293 (97%) were the main problems reported by respondents.  Conclusions: Although the majority of participants had an unsatisfactory level of knowledge and misperceptions about CTs, they showed an interest in and positive attitudes about conducting CTs.


Assuntos
Atitude do Pessoal de Saúde , Ensaios Clínicos como Assunto , Conhecimentos, Atitudes e Prática em Saúde , Médicos/psicologia , Adulto , Pesquisa Biomédica/organização & administração , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Centros de Atenção Terciária , Fatores de Tempo , Adulto Jovem
9.
Pain Pract ; 7(4): 348-51, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17986167

RESUMO

Myofascial pain syndrome (MPS) may persist for many years and is often refractory to traditional therapeutic approaches including pharmacotherapy, focal tenderness infiltration by local anesthetic and corticosteroids, physical therapy and behavioral modification. This report describes three cases of MPS following coronary artery bypass graft, inadequate positioning during abdominal hysterectomy, and excessive physical effort refractory to conventional therapeutic approaches. Three patients were successfully treated with repeated nerve stimulator-guided paravertebral block using a mixture of bupivacaine and clonidine. Physical examinations including a complete neurological assessments were unremarkable. Relevant diagnostic imaging (X-ray, magnetic resonance imaging, computed tomography) and laboratory evaluations also failed to demonstrate any significant structural disorders or systemic diseases that might have been responsible for their pain. Nerve stimulator-guided paravertebral block was performed at the dermatomes corresponding to the thoracic myofascial pain region. Each point was injected with 4 mL of the local anesthetic solution. If the pain returned, a second paravertebral block was performed. The three patients were pain-free over a follow-up period up to 2 years. Our report suggests that nerve stimulator-guided paravertebral blockade could be a useful treatment for MPS refractory to traditional therapeutic approaches.


Assuntos
Terapia por Estimulação Elétrica , Síndromes da Dor Miofascial/terapia , Bloqueio Nervoso/métodos , Nervos Torácicos/fisiologia , Idoso , Dor no Peito/terapia , Doença Crônica , Ponte de Artéria Coronária , Feminino , Humanos , Histerectomia , Masculino , Pessoa de Meia-Idade , Dor Pós-Operatória/terapia
10.
Saudi Med J ; 38(2): 209-212, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28133697

RESUMO

OBJECTIVES: To identify the prevalence and predictors of physical exercise among nurses. Methods: This study was conducted at 2 hospitals selected randomly from tertiary hospitals in King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia (KSA) and Makassed General Hospital, Beirut, Lebanon in 2014. The study included nurses with at least one year of nursing experience. Data were collected using a self-administered questionnaire. The questionnaire was divided into 2 sections, one covering the respondents' demographics, and the other one assessing the prevalence and the characteristics of physical exercise.  Results: A total of 412 participants responded, of whom 248 (60.2%) are engaged in physical exercise. On multivariate analysis, normal weight and smoking were independently associated with physical exercise. Most 66.1% of respondents reported practicing walking as the most common type of physical activity. One hundred eighty (72.6%) respondents relied on their own motivation to perform physical activity and 64.6% reported the lack of availability of physical activity facilities.  Conclusion: Smoking and obesity were the significant predictors associated with physical inactivity. Encouraging nurses to adopt a healthy lifestyle for their role modeling to patients as health promoters is recommended.


Assuntos
Exercício Físico , Enfermeiras e Enfermeiros/estatística & dados numéricos , Adolescente , Adulto , Estudos Transversais , Feminino , Humanos , Líbano , Masculino , Pessoa de Meia-Idade , Enfermeiras e Enfermeiros/psicologia , Prevalência , Arábia Saudita , Adulto Jovem
11.
Reg Anesth Pain Med ; 31(3): 196-201, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16701182

RESUMO

BACKGROUND AND OBJECTIVES: The purpose of this study was to assess the radiographic and clinical distribution of 1 to 4 paravertebral injections by use of the same total volume of local anesthetic mixture. METHODS: Sixty-nine patients scheduled for surgical interventions suitable for bilateral PVB were included in the study and were randomly assigned to 1 of 3 treatment groups. Group 1 received 4 paravertebral injections on one side versus 1 injection on the contralateral side (23 patients), group 2 received 4 injections versus 2 injections (23 patients), and group 3 received 4 injections versus 3 injections (23 patients). RESULTS: Sixty-one patients were included in the final analysis, which resulted in 368 thoracic paravertebral injections. Overall, 97% of the patients had adequate loss of sensation within the targeted area at the side of 4 injections, compared with only 11% for the single injections. The average vertical spread of contrast was found to be significantly greater in the set of 4 injections, with mean (SD) 6.5 (2.01) dermatomes, compared with the single injection, with 3.0 (1.19) dermatomes (P < .05). The average vertical spread of contrast and complete absence of sensation were significantly greater in the set of 4 injections compared with the set of 2 and 3 injections (P < .05). CONCLUSION: The main finding of the present study was that multiple paravertebral injections resulted in more reliable radiographic and clinical distribution compared with a single-injection technique.


Assuntos
Anestésicos Locais/administração & dosagem , Bloqueio Nervoso/métodos , Anestésicos Locais/farmacologia , Meios de Contraste , Esquema de Medicação , Feminino , Humanos , Injeções Espinhais , Masculino , Pessoa de Meia-Idade , Medição da Dor , Limiar da Dor/efeitos dos fármacos , Estudos Prospectivos , Radiografia Torácica , Vértebras Torácicas
12.
Pain Pract ; 6(4): 278-84, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17129309

RESUMO

PURPOSE: To evaluate the repetitive occipital nerve blocks using a nerve stimulator in the treatment of cervicogenic headache. METHODS: This prospective noncomparative clinical interventional case-series study included 47 patients suffering from cervicogenic headache using a repetitive guided occipital nerve blockade. RESULTS: Forty-one patients (87%) required more than one injection to achieve six-month pain-relief period. For every three years of headache history, the outcomes demonstrated that a patient needed one additional injection to the basic injection. CONCLUSION: The repeated nerve stimulator-guided occipital nerve blockade is a treatment mode that may relieve cervicogenic headache with no recurrence for at least six months in addition to alleviation of associated symptoms.


Assuntos
Anestésicos Locais/administração & dosagem , Bloqueio Nervoso/métodos , Cefaleia Pós-Traumática/tratamento farmacológico , Nervos Espinhais/efeitos dos fármacos , Adulto , Idoso , Bupivacaína/administração & dosagem , Vértebras Cervicais/fisiopatologia , Clonidina/administração & dosagem , Relação Dose-Resposta a Droga , Esquema de Medicação , Combinação de Medicamentos , Estimulação Elétrica , Eletrodiagnóstico , Feminino , Fentanila/administração & dosagem , Humanos , Lidocaína/administração & dosagem , Masculino , Pessoa de Meia-Idade , Cervicalgia/tratamento farmacológico , Cervicalgia/etiologia , Cervicalgia/fisiopatologia , Cefaleia Pós-Traumática/etiologia , Cefaleia Pós-Traumática/fisiopatologia , Estudos Prospectivos , Nervos Espinhais/fisiopatologia , Resultado do Tratamento
13.
Pain Pract ; 6(2): 89-95, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17309715

RESUMO

Cervicogenic headache is a chronic hemicranial pain, usually occurring daily. This randomized, double-blind, placebo-controlled trial evaluated the effectiveness of nerve stimulator-guided occipital nerve blockade in the treatment of cervicogenic headache. The reduction in analgesic consumption was the primary outcome measure. Fifty adult patients diagnosed with cervicogenic headache were randomly divided into two equal groups of 25 patients each. All patients in both groups received greater and lesser occipital blocks, whereas only 16 patients in each group received facial nerve blockade in association with the occipital blocks. The control group received injections of an equivalent volume of preservative-free normal saline. Pain was assessed using the visual analog scale (VAS) and the Total Pain Index (TPI). Forty-seven patients entered into the final analysis as three patients were lost to follow-up. Anesthetic block was effective in reducing the VAS and the TPI by approximately 50% from baseline values (P = 0.0001). Analgesic consumption, duration of headache and its frequency, nausea, vomiting, photophobia, phonophobia, decreased appetite, and limitations in functional activities were significantly less in block group compared to control group (P < 0.05). The nerve stimulator-guided occipital nerve blockade significantly relieved cervicogenic headache and associated symptoms at two weeks following injection.


Assuntos
Anestésicos Locais/uso terapêutico , Eletrodiagnóstico/métodos , Bloqueio Nervoso/métodos , Cefaleia Pós-Traumática/diagnóstico , Cefaleia Pós-Traumática/tratamento farmacológico , Nervos Espinhais/efeitos dos fármacos , Adulto , Bupivacaína/uso terapêutico , Vértebras Cervicais , Clonidina/uso terapêutico , Método Duplo-Cego , Combinação de Medicamentos , Estimulação Elétrica/instrumentação , Estimulação Elétrica/métodos , Eletrodos , Eletrodiagnóstico/instrumentação , Nervo Facial/efeitos dos fármacos , Nervo Facial/fisiopatologia , Nervo Facial/cirurgia , Feminino , Fentanila/uso terapêutico , Humanos , Lidocaína/uso terapêutico , Masculino , Pessoa de Meia-Idade , Músculos do Pescoço/inervação , Músculos do Pescoço/fisiopatologia , Cefaleia Pós-Traumática/fisiopatologia , Nervos Espinhais/fisiopatologia , Nervos Espinhais/cirurgia , Resultado do Tratamento
14.
PLoS One ; 11(2): e0143893, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26848750

RESUMO

AIM: To assess the knowledge, attitudes, and perceptions of Saudis towards participating in clinical trials (CTs). METHODS: A cross-sectional study was conducted on 232 Saudi adult patients and their companions visiting adult outpatient clinics at King Fahad Medical City, Riyadh, Saudi Arabia. Data were collected using a self-administered questionnaire based on information obtained from the literature. The questionnaire was divided into four sections, one covering the respondents' demographics, and the other three assessing knowledge, attitudes, and perceptions towards participating in CTs. RESULTS: A total of 148 (63.8%) respondents were males, and 52 (22.4%) participants had been invited to participate in a CT previously. Of those, 39 (75%) participated. Knowledge about the essential elements of informed consent ranged from 55.7% (number of participants needed) to 85.7% (confidentiality of personal information). The majority (163, 73.8%) of respondents was willing to participate in a CT after consulting their family physician and 130 (58.0%) respondents would be motivated to participate in a CT if they were healthy. Only 36.8% of the respondents believed that patients who participated in a CT received the best care. Moreover, 110 (48.7%) respondents believed that research was conducted in a responsible and ethical manner. CONCLUSIONS: The present study assessed the current understanding of CTs among Saudi participants. Although the majority of participants had an acceptable level of knowledge about CTs, they exhibited conditional attitudes and misperceptions towards participating in a CT. Increased patient awareness may improve patients' attitudes towards ethical conduct of CTs.


Assuntos
Ensaios Clínicos como Assunto , Conhecimentos, Atitudes e Prática em Saúde , Aceitação pelo Paciente de Cuidados de Saúde , Percepção , Adolescente , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Arábia Saudita , Adulto Jovem
15.
Clin Nutr ; 32(2): 193-9, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22981241

RESUMO

BACKGROUND & AIM: Acute lower respiratory infections are the most frequent illnesses globally in children less than 5 years old. The aim of this randomized double blind controlled trial is to assess the effectiveness of zinc gluconate supplementation for 2 months period compared to placebo in reducing respiratory morbidity in acute lower respiratory infected children up to 5 years of age living in zinc poor population. METHODS: Children were randomly assigned to receive either 10 mg zinc gluconate or placebo for 60 days. Demographic and clinical data were collected at baseline and every two weeks for 180 days. RESULTS: The final analysis included 96 children allocated equally to the two groups. The number of episodes of acute lower respiratory infections and severe acute lower respiratory infections were significantly lower in zinc group compared to placebo group (20.8% vs. 45.8% (P = 0.009) and 21.7% vs. 58.3% (P < 0.001), respectively). The acute lower respiratory infections free days were higher in the zinc supplemented group (P < 0.001). The median recovery time of morbidity was significantly shorter in zinc group (P < 0.001). CONCLUSIONS: Zinc supplement may result in significant reduction in respiratory morbidity among children with acute lower respiratory infections in zinc poor population. This study was registered under ClinicalTrials.gov Identifier no. NCT00536133.


Assuntos
Suplementos Nutricionais , Gluconatos/administração & dosagem , Infecções Respiratórias/prevenção & controle , Zinco/administração & dosagem , Doença Aguda , Pré-Escolar , Método Duplo-Cego , Feminino , Humanos , Masculino , Morbidade , Zinco/deficiência
16.
PLoS One ; 8(1): e52929, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23349694

RESUMO

BACKGROUND: Emerging epidemiological evidence suggests that statins may reduce the risk of community-acquired pneumonia (CAP) and its complications. PURPOSE: Performed a systematic review to address the role of statins in the prevention or treatment of CAP. DATA SOURCE: Ovid MEDLINE, Cochrane, EMBASE, ISI Web of Science, and Scopus from inception through December 2011 were searched for randomized clinical trials, cohort and case-control studies. STUDY SELECTION: Two authors independently reviewed studies that examined the role of statins in CAP. DATA EXTRACTION: Data about study characteristics, adjusted effect-estimates and quality characteristics was extracted. DATA SYNTHESIS: Eighteen studies corresponding to 21 effect-estimates (eight and 13 of which addressed the preventive and therapeutic roles of statins, respectively) were included. All studies were of good methodological quality. Random-effects meta-analyses of adjusted effect-estimates were used. Statins were associated with a lower risk of CAP, 0.84 (95% CI, 0.74-0.95), I(2) = 90.5% and a lower short-term mortality in patients with CAP, 0.68 (95% CI, 0.59-0.78), I(2) = 75.7%. Meta-regression did not identify sources of heterogeneity. A funnel plot suggested publication bias in the treatment group, which was adjusted by a novel regression method with a resultant effect-estimate of 0.85 (95% CI, 0.77-0.93). Sensitivity analyses using the rule-out approach showed that it is unlikely that the results were due to an unmeasured confounder. CONCLUSIONS: Our meta-analysis reveals a beneficial role of statins for the risk of development and mortality associated with CAP. However, the results constitute very low quality evidence as per the GRADE framework due to observational study design, heterogeneity and publication bias.


Assuntos
Infecções Comunitárias Adquiridas/tratamento farmacológico , Infecções Comunitárias Adquiridas/prevenção & controle , Inibidores de Hidroximetilglutaril-CoA Redutases/farmacologia , Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico , Pneumonia/tratamento farmacológico , Pneumonia/prevenção & controle , Humanos
17.
J Egypt Public Health Assoc ; 86(3-4): 73-6, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21844763

RESUMO

BACKGROUND: The risks and safety of cesarean section (CS) differ from place to place in the world. According to the World Health Organization, the best outcomes for mothers and babies appear to occur with CS rates of 5-15%. Increasing maternal age and high parity are among the chief determinants of cesarean deliveries. MATERIALS AND METHODS: A retrospective cohort study was done at the tertiary care facility, King Fahd Medical City, Riyadh from 1 January to 31 December 2008. Observations were recorded from the labor ward registers. Sample size estimated was n=2192. A total of 2907 patients were recruited. All CS at viable gestation were included. Vaginal deliveries were taken as the comparison group. Non probability convenient sampling was done. Factors associated with cesarean deliveries were analyzed using univariate and bivariate analysis methods. Level of significance was set at P≤0.05 and confidence interval (CI)=95% respectively. RESULTS: Independent sample t test and Pearson's chi-square test showed that increasing maternal age, parity (P=0.0001 and 0.002 respectively), and prematurity (P=0.0001) were significant associates for CS. Binary logistic regression also confirmed significant association of increasing parity and prematurity (P=0.02 and 0.0001 respectively). Non-reassuring cardiotocography was the most common indication for CS. CONCLUSION AND RECOMMENDATIONS: Increasing maternal age and parity as well as prematurity were the factors significantly associated with CS. Fetomaternal outcome was comparable between vaginal and abdominal deliveries, despite the high CS rate. Non-reassuring cardiotocography was the most common indication. Secondary tests for evaluation of fetal well being might help to reduce the high CS rate.


Assuntos
Cesárea , Idade Materna , Fatores Etários , Estudos de Coortes , Feminino , Humanos , Gravidez , Estudos Retrospectivos , Arábia Saudita
18.
Oman Med J ; 26(5): 353-5, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22125731

RESUMO

Transient osteoporosis of the hip (TOH) is a rare condition mainly affecting pregnant women in their third trimester and middle aged men. We report a case of TOH/Bone marrow edema syndrome in pregnancy with involvement of the surrounding soft tissues on magnetic resonance image, which has not been previously reported. The presence of such edema in the soft tissues may help to differentiate this condition from early avascular necrosis of the hip, and may also provide an insight into the pathogenesis of the condition. The reported patient was treated conservatively and fully recovered.

20.
Paediatr Anaesth ; 15(11): 964-70, 2005 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16238558

RESUMO

BACKGROUND: Several techniques have been used for alleviating post-circumcision pain with regional anesthetics being more effective than systemic opioids. Our aim was to compare the effectiveness of dorsal penile block, ring block (RB) and dorsal penile block associated with RB in reducing post-circumcision pain in children. METHODS: We conducted a prospective randomized double-blind clinical trial on 100 boys aged between 1 month and 5 years undergoing elective circumcision. Each 20 ml of local anesthetic mixture contained 9 ml lidocaine 1% without epinephrine, 9 ml bupivacaine 0.5%, 1 ml fentanyl (50 microg.ml(-1)) and 1 ml clonidine (75 microg.ml(-1)). They were allocated to one of three groups: 33 boys were given a RB with 1-1.5 ml (group 1), 32 had a dorsal penile block with 1.5-4 ml (group 2) and 35 had a combined ring and dorsal penile block with 2.5-5 ml of anesthetic mixture based on the child's age. RESULTS: Ninety-one children (91%) completed the clinical trial (three failed blocks and six follow-up losses). The groups were similar with regard to age, weight, height, duration of surgery and hemodynamic status. The average pain scores were significantly higher with a RB compared with the other two groups (P < 0.05) for the first postoperative day. RB children and dorsal penile block children consumed significantly more analgesics for the first six postoperative hours (P < 0.05). The surgeon's satisfaction was significantly higher with the ring + dorsal penile block group (100%) compared with the other two groups (P = 0.032). CONCLUSION: Dorsal penile block plus RB technique is superior to dorsal penile block alone and RB alone in reducing postcircumcision pain in children.


Assuntos
Anestesia por Condução/métodos , Circuncisão Masculina , Clonidina/uso terapêutico , Fentanila/uso terapêutico , Analgésicos/uso terapêutico , Pré-Escolar , Método Duplo-Cego , Humanos , Lactente , Masculino
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