Detalhe da pesquisa
1.
Preclinical characterization of pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor.
Blood
; 142(1): 62-72, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36796019
2.
Identification of LACTB2, a metallo-ß-lactamase protein, as a human mitochondrial endoribonuclease.
Nucleic Acids Res
; 44(4): 1813-32, 2016 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26826708
3.
Method for rapid optimization of recombinant GPCR protein expression and stability using virus-like particles.
Protein Expr Purif
; 133: 41-49, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28263854
4.
The structures of the SNM1A and SNM1B/Apollo nuclease domains reveal a potential basis for their distinct DNA processing activities.
Nucleic Acids Res
; 43(22): 11047-60, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26582912
5.
Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.
Nucleic Acids Res
; 43(10): 5221-35, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25901030
6.
Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev: DETERMINANTS OF DNA BINDING AND REDOX REGULATION BY DISULFIDE BOND FORMATION.
J Biol Chem
; 290(22): 13692-709, 2015 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25866208
7.
A new small molecule inhibitor of soluble guanylate cyclase.
Bioorg Med Chem
; 23(17): 5303-10, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26264842
8.
Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population.
Br J Clin Pharmacol
; 77(5): 839-51, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24028545
9.
Surface plasmon resonance using the catalytic domain of soluble guanylate cyclase allows the detection of enzyme activators.
Bioorg Med Chem Lett
; 24(4): 1075-9, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24480469
10.
Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases.
J Biol Chem
; 287(31): 26254-67, 2012 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22692201
11.
Dataset on Galanin Receptor 3 mutants that improve recombinant receptor expression and stability in an agonist and antagonist bound form.
Data Brief
; 12: 603-607, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28540352
12.
Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations.
Sci Rep
; 7(1): 7501, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790404
13.
Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
J Med Chem
; 60(8): 3472-3483, 2017 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28406621
14.
Crystal structures of the catalytic domain of human soluble guanylate cyclase.
PLoS One
; 8(3): e57644, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23505436
15.
Improved genetically-encoded, FlincG-type fluorescent biosensors for neural cGMP imaging.
Front Mol Neurosci
; 6: 26, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24068983
16.
Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations.
Structure
; 21(7): 1182-92, 2013 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23791943
17.
Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation.
N Biotechnol
; 29(5): 515-25, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22027370
18.
Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.
J Med Chem
; 53(5): 2215-26, 2010 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20151671
19.
Molecular evolution and balancing selection in the flavin-containing monooxygenase 3 gene (FMO3).
Pharmacogenet Genomics
; 17(10): 827-39, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17885620