Detalhe da pesquisa
1.
PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.
Cell
; 171(3): 628-641.e26, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29053969
2.
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators.
Proc Natl Acad Sci U S A
; 120(25): e2218896120, 2023 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37327313
3.
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death.
Angew Chem Int Ed Engl
; 63(9): e202314710, 2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38230815
4.
Phospholipase iPLA2ß averts ferroptosis by eliminating a redox lipid death signal.
Nat Chem Biol
; 17(4): 465-476, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33542532
5.
Successive High-Resolution (H2O)n-GCIB and C60-SIMS Imaging Integrates Multi-Omics in Different Cell Types in Breast Cancer Tissue.
Anal Chem
; 93(23): 8143-8151, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34075742
6.
Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spectrometry (GCIB-SIMS).
Angew Chem Int Ed Engl
; 60(21): 11784-11788, 2021 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33684237
7.
Lipidomics Detection of Brain Cardiolipins in Plasma Is Associated With Outcome After Cardiac Arrest.
Crit Care Med
; 47(4): e292-e300, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30855329
8.
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.
Nat Chem Biol
; 13(1): 81-90, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27842066
9.
Secondary-Ion Mass Spectrometry Images Cardiolipins and Phosphatidylethanolamines at the Subcellular Level.
Angew Chem Int Ed Engl
; 58(10): 3156-3161, 2019 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30680861
10.
Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE.
J Am Chem Soc
; 140(51): 17835-17839, 2018 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525572
11.
Gas Cluster Ion Beam Time-of-Flight Secondary Ion Mass Spectrometry High-Resolution Imaging of Cardiolipin Speciation in the Brain: Identification of Molecular Losses after Traumatic Injury.
Anal Chem
; 89(8): 4611-4619, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28306235
12.
Global assessment of oxidized free fatty acids in brain reveals an enzymatic predominance to oxidative signaling after trauma.
Biochim Biophys Acta Mol Basis Dis
; 1863(10 Pt B): 2601-2613, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28347845
13.
Known unknowns of cardiolipin signaling: The best is yet to come.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(1): 8-24, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27498292
14.
Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression.
J Neurosci
; 35(34): 12002-17, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26311780
15.
Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity.
Am J Physiol Lung Cell Mol Physiol
; 311(2): L303-16, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27233995
16.
Imaging mass spectrometry reveals loss of polyunsaturated cardiolipins in the cortical contusion, hippocampus, and thalamus after traumatic brain injury.
J Neurochem
; 139(4): 659-675, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27591733
17.
Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch.
J Biol Chem
; 288(1): 111-21, 2013 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23150663
18.
PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression.
Cell Metab
; 36(4): 762-777.e9, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38309267
19.
Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin.
Biochim Biophys Acta
; 1818(10): 2413-23, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22464971
20.
Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo.
Redox Biol
; 61: 102650, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870109