Detalhe da pesquisa
1.
Designing Potent Anti-Cancer Agents: Synthesis and Molecular Docking Studies of Thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidine Derivatives.
Molecules
; 29(5)2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38474579
2.
In Silico Targeting of Fascin Protein for Cancer Therapy: Benchmarking, Virtual Screening and Molecular Dynamics Approaches.
Molecules
; 28(3)2023 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36770963
3.
Design and synthesis of new 2-oxoquinoxalinyl-1,2,4-triazoles as antitumor VEGFR-2 inhibitors.
Bioorg Chem
; 121: 105696, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217379
4.
Antibacterial and anticancer profiling of new benzocaine derivatives: Design, synthesis, and molecular mechanism of action.
Arch Pharm (Weinheim)
; 355(4): e2100451, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35102593
5.
Nourin-Associated miRNAs: Novel Inflammatory Monitoring Markers for Cyclocreatine Phosphate Therapy in Heart Failure.
Int J Mol Sci
; 22(7)2021 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33808213
6.
Marine Brominated Tyrosine Alkaloids as Promising Inhibitors of SARS-CoV-2.
Molecules
; 26(20)2021 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34684755
7.
Selective VEGFR-2 inhibitors: Synthesis of pyridine derivatives, cytotoxicity and apoptosis induction profiling.
Bioorg Chem
; 103: 104222, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32889383
8.
Synthesis and in vitro investigation of novel cytotoxic pyrimidine and pyrazolopyrimidne derivatives showing apoptotic effect.
Bioorg Chem
; 96: 103621, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32036162
9.
New benzenesulfonamide scaffold-based cytotoxic agents: Design, synthesis, cell viability, apoptotic activity and radioactive tracing studies.
Bioorg Chem
; 96: 103577, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31978683
10.
Design and molecular modeling of novel P38α MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds.
Bioorg Med Chem
; 27(7): 1308-1319, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30792101
11.
The molecular basis of cytotoxicity of α-spinasterol from Ganoderma resinaceum: Induction of apoptosis and overexpression of p53 in breast and ovarian cancer cell lines.
J Cell Biochem
; 119(5): 3892-3902, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29143969
12.
Personalized Medicine and Resurrected Hopes for the Management of Alzheimer's Disease: A Modular Approach Based on GSK-3ß Inhibitors.
Adv Exp Med Biol
; 1007: 199-224, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28840559
13.
Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives.
J Enzyme Inhib Med Chem
; 31(6): 1612-8, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27052554
14.
Cytotoxic activity of some novel sulfonamide derivatives.
Acta Pol Pharm
; 72(1): 79-87, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25850203
15.
Design, synthesis and molecular docking of novel N,N-dimethylbenzenesulfonamide derivatives as potential antiproliferative agents.
J Enzyme Inhib Med Chem
; 29(5): 619-27, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24090422
16.
Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel cyanoenone and enone benzenesulfonamides.
J Enzyme Inhib Med Chem
; 29(6): 840-5, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24417210
17.
Gamma Secretase as an Important Drug Target for Management of Alzheimer's Disease: A Comprehensive Review.
Curr Top Med Chem
; 24(2): 109-127, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-37818580
18.
Exploring a repurposed candidate with dual hIDO1/hTDO2 inhibitory potential for anticancer efficacy identified through pharmacophore-based virtual screening and in vitro evaluation.
Sci Rep
; 14(1): 9386, 2024 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38653790
19.
Unleashing new MTDL AChE and BuChE inhibitors as potential anti-AD therapeutic agents: In vitro, in vivo and in silico studies.
Int J Biol Macromol
; 268(Pt 1): 131740, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38653428
20.
Discovery of Quinolinone Hybrids as Dual Inhibitors of Acetylcholinesterase and Aß Aggregation for Alzheimer's Disease Therapy.
ACS Chem Neurosci
; 15(3): 539-559, 2024 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38149821