Detalhe da pesquisa
1.
A Multicenter, Randomized, Double-Blind, Phase 2 Study of the Efficacy and Safety of Plazomicin Compared with Levofloxacin in the Treatment of Complicated Urinary Tract Infection and Acute Pyelonephritis.
Antimicrob Agents Chemother
; 62(4)2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378708
2.
In Vitro Activity of Ceftolozane-Tazobactam against Anaerobic Organisms Identified during the ASPECT-cIAI Study.
Antimicrob Agents Chemother
; 60(1): 666-8, 2016 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26552971
3.
Outcomes of high-dose levofloxacin therapy remain bound to the levofloxacin minimum inhibitory concentration in complicated urinary tract infections.
BMC Infect Dis
; 16(1): 710, 2016 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27887579
4.
Activity of ACHN-490 tested alone and in combination with other agents against Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 55(5): 2463-5, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21282445
5.
BTI1, an azoreductase with pH-dependent substrate specificity.
Appl Environ Microbiol
; 77(12): 4223-5, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21531830
6.
Synthesis and spectrum of the neoglycoside ACHN-490.
Antimicrob Agents Chemother
; 54(11): 4636-42, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20805391
7.
ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates.
Antimicrob Agents Chemother
; 53(10): 4504-7, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19770287
8.
Detection of methyltransferases conferring high-level resistance to aminoglycosides in enterobacteriaceae from Europe, North America, and Latin America.
Antimicrob Agents Chemother
; 52(5): 1843-5, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18347105
9.
Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogs.
ACS Chem Biol
; 9(9): 2067-73, 2014 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25019242
10.
Hybrid aminoglycoside antibiotics via Tsuji palladium-catalyzed allylic deoxygenation.
Org Lett
; 13(24): 6476-9, 2011 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22085292
11.
Activity of ACHN-490 against meticillin-resistant Staphylococcus aureus (MRSA) isolates from patients in US hospitals.
Int J Antimicrob Agents
; 38(4): 352-4, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21820877
12.
Toward Overcoming Staphylococcus aureus Aminoglycoside Resistance Mechanisms with a Functionally Designed Neomycin Analogue.
ACS Med Chem Lett
; 2(12): 924-8, 2011 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900282
13.
Combating evolution with intelligent design: the neoglycoside ACHN-490.
Curr Opin Microbiol
; 13(5): 565-73, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20932796