Detalhe da pesquisa
1.
Evaluation of iberdomide and cytochrome p450 drug-drug interaction potential in vitro and in a phase 1 study in healthy subjects.
Eur J Clin Pharmacol
; 77(2): 223-231, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32965548
2.
Absorption, distribution, metabolism, and excretion of mTOR kinase inhibitor CC-223 in rats, dogs, and humans.
Xenobiotica
; 49(1): 43-53, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29206565
3.
Assessment of drug-drug interaction potential and PBPK modeling of CC-223, a potent inhibitor of the mammalian target of rapamycin kinase.
Xenobiotica
; 49(1): 54-70, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29297772
4.
Absorption, distribution, metabolism and excretion of an isocitrate dehydrogenase-2 inhibitor enasidenib in rats and humans.
Xenobiotica
; 49(2): 200-210, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29320949
5.
In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism.
Xenobiotica
; 45(6): 465-80, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25475995
6.
Metabolism and disposition of a potent and selective JNK inhibitor [14C]tanzisertib following oral administration to rats, dogs and humans.
Xenobiotica
; 45(5): 428-41, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25482583
7.
Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approach.
Mol Cell Proteomics
; 9(7): 1400-10, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20233844
8.
Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites.
Mol Cell Proteomics
; 8(3): 467-80, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18984578
9.
Intramolecular transacylation: fragmentation of protonated molecules via ion-neutral complexes in mass spectrometry.
Rapid Commun Mass Spectrom
; 23(13): 1970-6, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19504483
10.
A novel serine phosphorylation site detected in the N-terminal domain of estrogen receptor isolated from human breast cancer cells.
J Am Soc Mass Spectrom
; 19(5): 729-40, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18367407
11.
Reactivity of zinc finger cysteines: chemical modifications within labile zinc fingers in estrogen receptor.
J Am Soc Mass Spectrom
; 16(12): 2017-26, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16246571
12.
Quantification of cysteine oxidation in human estrogen receptor by mass spectrometry.
Anal Chem
; 79(8): 3083-90, 2007 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17373775
13.
Novel pathways associated with quinone-induced stress in breast cancer cells.
Drug Metab Rev
; 38(4): 601-13, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17145690
14.
Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylation.
Mol Pharmacol
; 68(3): 606-15, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15939799