Detalhe da pesquisa
1.
Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state.
Brain
; 144(4): 1167-1182, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33842937
2.
The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo.
Int J Mol Sci
; 22(13)2021 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34201785
3.
The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo.
Neurobiol Dis
; 134: 104614, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31605779
4.
Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat.
Brain
; 141(2): 535-549, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29253129
5.
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Brain
; 141(5): 1434-1454, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534157
6.
Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant -7m8.
Biotechnol Bioeng
; 113(12): 2712-2724, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27259396
7.
High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes.
Stem Cells
; 31(9): 1816-28, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23712629
8.
Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter.
Hum Mol Genet
; 20(12): 2422-34, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21493629
9.
Human and simian immunodeficiency viruses deregulate early hematopoiesis through a Nef/PPARgamma/STAT5 signaling pathway in macaques.
J Clin Invest
; 118(5): 1765-75, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18431514
10.
Reconstitution of the myeloid and lymphoid compartments after the transplantation of autologous and genetically modified CD34+ bone marrow cells, following gamma irradiation in cynomolgus macaques.
Retrovirology
; 5: 50, 2008 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18565229
11.
Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease.
Acta Neuropathol Commun
; 6(1): 104, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322407
12.
Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing.
Mol Ther Methods Clin Dev
; 5: 259-276, 2017 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28603746
13.
[Nef and PPAR-gamma interact to suppress Stat5 expression in CD34+ progenitors from infected macaques]. / Vers un nouveau rôle du récepteur PPAR-gamma dans le syndrome d'immunodéficience acquise et les hémopathies chez l'homme.
Med Sci (Paris)
; 24(5): 551-3, 2008 May.
Artigo
em Francês
| MEDLINE | ID: mdl-18466737
14.
Improved protection against simian immunodeficiency virus mucosal challenge in macaques primed with a DNA vaccine and boosted with the recombinant modified vaccinia virus Ankara and recombinant Semliki Forest virus.
Vaccine
; 26(4): 532-45, 2008 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18093703