Detalhe da pesquisa
1.
Mutation-specific downregulation of CFTR2 variants by gating potentiators.
Hum Mol Genet
; 26(24): 4873-4885, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29040544
2.
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.
J Biol Chem
; 292(50): 20657-20668, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29061851
3.
Correctors and Potentiators Rescue Function of the Truncated W1282X-Cystic Fibrosis Transmembrane Regulator (CFTR) Translation Product.
J Biol Chem
; 292(3): 771-785, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27895116
4.
The scheduling of adolescence with Netrin-1 and UNC5C.
bioRxiv
; 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711625
5.
Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice.
Nat Commun
; 14(1): 4035, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37419977
6.
Mutation-specific dual potentiators maximize rescue of CFTR gating mutants.
J Cyst Fibros
; 19(2): 236-244, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31678009
7.
Structure-guided combination therapy to potently improve the function of mutant CFTRs.
Nat Med
; 24(11): 1732-1742, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297908
8.
Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell.
Nat Commun
; 8(1): 398, 2017 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855508
9.
From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.
Mol Biol Cell
; 27(3): 424-33, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26823392
10.
Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression.
Sci Transl Med
; 6(246): 246ra97, 2014 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25101887